1.
Archives of Iranian Medicine. 2000; 3 (3): 151-3
in English
| IMEMR
| ID: emr-53433
ABSTRACT
Robertsonian translocation is one of the major chromosomal re-arrangements and comprises 18% of total genetic abnormalities. It occurs between different chromosomes and chromosomal segments and less than 0.2% of individuals carry a symptomatic chromosomal rearrangement. However, the t[22;22]is a rare phenomenon which mainly manifests as familial monosomy or trisomy. We report on a 30-year old woman who was referred to a pathological laboratory in Kerman, Iran. She had no mental retardation, but suffered from repeated abortions. On the basis of GTG-banding and karyotyping, it was found that a Robertsonian translocation in the chromosome 22;22 was the primary cause of this syndrome