ABSTRACT
Since ancient times, various herbal medicines have been used in folk medicine to treat a variety of diseases. While the majority of drugs belong to the Kingdom of Plantae, some drugs from the Kingdom of Animalia are listed in various Materia medica of alternative medicines. Animal-derived drugs are mentioned in the Unani system of Medicine (USM) and have been used successfully to treat a variety of diseases. Marjan (Corallium rubrum) is a vital marine drug of animal origin that has been used in USM since ancient times and continues to be used today. It possesses a variety of beneficial pharmacological properties, including tonic effects on the heart, brain, stomach, and eyes, pregnancy protection, expectorant, and hemostyptic properties. It is used to treat hemoptysis, palpitation, bleeding piles, hemiplegia, heart failure, and general weakness. It is also an ingredient in a variety of Unani formulations with pharmacological significance. Unani physicians expanded the uses of Marjan and successfully used it to treat a variety of new diseases. There is a dearth of scientific research on its pharmacological and medicinal properties. The urgent need is to validate the Unani claims about its beneficial cardiac and nervine actions, as well as other significant actions mentioned in the Unani literature.
ABSTRACT
Since ancient times, various herbal medicines have been used in folk medicine to treat a variety of diseases. While the majority of drugs belong to the Kingdom of Plantae, some drugs from the Kingdom of Animalia are listed in various Materia medica of alternative medicines. Animal-derived drugs are mentioned in the Unani system of Medicine (USM) and have been used successfully to treat a variety of diseases. Marjan (Corallium rubrum) is a vital marine drug of animal origin that has been used in USM since ancient times and continues to be used today. It possesses a variety of beneficial pharmacological properties, including tonic effects on the heart, brain, stomach, and eyes, pregnancy protection, expectorant, and hemostyptic properties. It is used to treat hemoptysis, palpitation, bleeding piles, hemiplegia, heart failure, and general weakness. It is also an ingredient in a variety of Unani formulations with pharmacological significance. Unani physicians expanded the uses of Marjan and successfully used it to treat a variety of new diseases. There is a dearth of scientific research on its pharmacological and medicinal properties. The urgent need is to validate the Unani claims about its beneficial cardiac and nervine actions, as well as other significant actions mentioned in the Unani literature.
ABSTRACT
Ankylosing spondylitis (AS) is a form of spondylitis in which spine is affected primarily along with otherjoints. The vertebrae fuse together and form a rigid structure. Individuals with AS are also positive for humanleukocyte antigen (HLA) B-27. One hundred and eighty-three symptomatic patients of AS were used in thestudy. Sequence-specific priming (SSP) PCR technique was used to detect the HLA B-27 specific allele. Thisstudy showed (out of 183 suspected cases, 45 cases were detected positive with HLA B-27 allele, while theremaining 138 were negative) that the positivity rate for AS with HLA B-27 allele is less. In 183 cases, 63were females, whereas 7 cases were positive and 56 negative, whereas 38 cases were positive for male and 82cases were negative. When sample was analyzed in term of age groups, it was found that out of 45 positivesamples, the positivity rate was maximum, i.e., 57.14% in the patient above 37 years of age. Furthermore, itwas observed that the males above 30 years are more prone to develop AS with HLA B27 specific allele. Forthe diagnosis of AS, conventional PCR technology is a promising diagnostic method and can be considered asan important tool along with other diagnostics parameters.