ABSTRACT
The term "alien hand syndrome (AHS)" comprises many clinical signs of which the common features are the involuntary motor movement of the affected limb and the denial of limb ownership. It can result from several diseases involving corpus callosum or medial frontal cortex. Two major types of AHS were previously classified, callosal and frontal types. Moreover posterior subtype of which the lesions do not involve corpus callosum have been reported. In the present report, the authors describe a 57-year-old man with AHS, aggressive behavior and hemispatial neglect which are the rare manifestations of callosal damage. Neuroimaging demonstrated subacute infarction of entire corpus callosum from the rostrum to splenium. A review of the literature on these abnormalities is included in the present paper.
Subject(s)
Apraxia, Ideomotor/etiology , Cerebral Infarction/psychology , Corpus Callosum , Dyskinesias/etiology , Hand , Humans , Male , Middle Aged , SyndromeABSTRACT
Serotonin syndrome is a severe but preventable adverse drug reaction. This syndrome is rare and usually underrecognized. It is resulted from the excessive serotonin receptor stimulation, mostly by combination of serotonergic agents. The clinical triads are altered mental status, autonomic dysfunction and neuromuscular abnormalities. Occasionally, severe cases of serotonin syndrome are complicated by rhabdomyolysis and other potentially life-threatening conditions. In this report, we describe a 22-year-old man presenting with serotonin syndrome and rhabdomyolysis from serotonergic drug interaction. In addition, recommendation of preventive strategies is included.