ABSTRACT
Azadirachta indica have been widely used in traditional systems of medicine for a variety of diseases. In the present study, Cow urine extract of Azadirachta indica was evaluated for its antimicrobial activity against MDR Clinical isolates. Antimicrobial activity was evaluated towards five MDR pathogenic strains of bacteria. The results indicated that Cow urine extract of A.indica more antibacterial activity in comparison of its organic fraction for MDR E.coli and, Klebseilla pneumonia . The phytochemical test suggests that constituents for all the 20 days were positive for flavonoids, alkaloids, quinine, coumarin, tannin, saponin and phenol. Antimicrobial activities were correlated with chemical compositions of both organic extracts and Cow urine extract of A. indica.