ABSTRACT
Coronavirus disease 2019 (COVID-19), characterized by high infectivity and invisibility, has spread quickly throughout the world and brought great challenges to hospital security work. Regarding the medical service reality of large general hospitals, the Security Department actively responded to the epidemic prevention and control work. They classified the risk areas in the hospital and formulated corresponding security strategies. Current paper summarize the improvement of the existing security management and control system, the management level of major public health emergencies and the emergency management. Then the control measures for scientific deployment of personnel and proper planning of the diagnosis and treatment process of risk patients during the epidemic are discussed. This study aimed to provide helpful reference for ensuring the stability of medical reception order in large general hospitals under COVID-19 epidemic.