ABSTRACT
Research Question: 1. What is the magnitude of problem of Goiter? 2. What is the level of iodised salt consumed by school children at school & home? Objectives: 1. To find out incidence of Goiter. 2. To find out level of iodised salt consumed by school children at school & home. Study Design: Cross-sectional study. Settings: School & houseto- house survey of urban & rural area of Raichur district. Participant: School children & general population of both sexes. Sample size: 45173. Statistical analysis: Proportion & Chi-squared test. Results: Total population covered 45173 in five talukas. Males were 23463 & females 21730, adult population 16404, children more than 15 yrs were 28769 & school population was 24984. School boys were 14269 & girls 10715. Highest prevalence of goiter found in Raichur taluka i.e. 5.68% and lowest in Lingsur taluka i.e. 0.86%. Over all prevalence of Goiter among surveyed villages is found to be 3.19 % (1439 cases). Higher prevalence has been reported among females in age group of 10- 14 yrs 5.25% & 15-19 yrs 4.66% compared to other age groups of village population. School children in Raichur district revealed the prevalence of Goiter 3.66%. Conclusion: Prevalence of Goiter among surveyed villages is found to be 3.19 % (1439 cases), which is less compared to the National figures. The people are consuming the iodated salt and ban on non-iodated salt may be effectively implemented in study region.
Subject(s)
Adolescent , Child , Female , Goiter/diagnosis , Goiter/epidemiology , Goiter, Endemic/diagnosis , Goiter, Endemic/epidemiology , Humans , India/epidemiology , Iodine/deficiency , Iodine/diagnosis , Male , Prevalence , Rural Population , Schools , Young AdultABSTRACT
In this study, Absorption factor method have been developed and validated for the simultaneous determination of perindopril erbumine and amlodipine besylate in their combined pharmaceutical formulation dosage form. Absorption factor method was performed for perindopril erbumine and amlodipine besylate at wavelength maxima 215 nm and 237 nm respectively. Amlodipine besylate was show liner at 237 nm but Amlodipine besylate also showed absorbance at 215nm and give interference in determination of Perindopril erbumine. Quantitative estimation of Perindopril erbumine was carried out by subtracting interference of Amlodipine besylate using experimentally calculated absorption factor. Result of analysis was validated by statistically. The result of the studies showed that the proposed Spectroscopic method is simple, rapid, precise and accurate, which can be used for the routine determination of Perindopril erbumine and Amlodipine besylate in bulk and in its pharmaceutical formulation.