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Rev. colomb. reumatol ; 29(4)oct.-dic. 2022.
Article in English | LILACS | ID: biblio-1536203

ABSTRACT

Systemic lupus erythematosus (SLE) is a systemic disease mediated by immune complexes of unknown aetiology that generates excessive production of autoantibodies against components of the cell nucleus, generating multisystemic involvement affecting organs or systems such as the central nervous, cardiovascular, haematolymphoid, musculoskeletal, kidney, serous, skin and subcutaneous tissue cells, among others. 2-Fluoro-2-deoxyglucose (FDG) is a glucose analogue that has been shown to be a useful diagnostic tool to establish the initial systemic involvement of this disease and response to the various treatments used.


El lupus eritematoso sistémico (LES) es una enfermedad sistémica mediada por inmunocomplejos de etiología desconocida, la cual genera una producción excesiva de autoanticuerpos contra componentes del núcleo celular. Esto último conlleva un compromiso multisistémico que afecta a órganos o sistemas como el nervioso central, el cardiovascular, el hematolinfoide, el musculoesquelético, el rinón, las serosas, la piel y el tejido celular subcutáneo, entre otros. La 2-fluoro-2-desoxiglucosa (FDG) es un análogo de la glucosa que ha mostrado ser una herramienta diagnostica útil para establecer el compromiso sistémico inicial de esta enfermedad y la respuesta a los diversos tratamientos.


Subject(s)
Humans , Female , Diagnostic Imaging , Skin and Connective Tissue Diseases , Connective Tissue Diseases , Diagnostic Techniques and Procedures , Positron Emission Tomography Computed Tomography , Lupus Erythematosus, Systemic
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