ABSTRACT
<p><b>OBJECTIVE</b>To explore a sampling method which could reflect iodine deficiency disorders (IDD) status at provincial level and discover risk areas with non-iodized salt problem.</p><p><b>METHOD</b>Baseline data of Iodized salt from Gansu and Fujian provinces were analyzed with Monte Carlo method both at county and prefecture levels respectively. True positive rate and false positive rate were also calculated.</p><p><b>RESULTS</b>With data from 7 - 8 villages or 4 - 5 townships counties at risk could be discovered. The true positive rate was around 80% and false positive rate was around 20%. At prefecture level, when randomly selecting and checking 3 counties, the samples would satisfy the discovery of all the risk areas with non-iodized salt problem.</p><p><b>CONCLUSIONS</b>We suggested that the sampling method of iodized salt investigation in national IDD surveillance as follows: to randomly choose 3 counties at each prefecture, 4 townships at each county, 2 villages at each township and 10 salt samples by household survey. The coverage rate of iodized salt in a province could be calculated by post-weighted method with population number.</p>
Subject(s)
Humans , China , Drug Monitoring , Methods , Iodine , Pharmacology , Monte Carlo Method , Sodium Chloride, Dietary , PharmacologyABSTRACT
<p><b>OBJECTIVE</b>To investigate the neonatal umbilical cord blood thyroid stimulating hormone (TSH) level in the universal iodized salt areas and put forward the cut-point, then analyze its application.</p><p><b>METHODS</b>Seven provinces were selected where the pregnant women having satisfied urinary iodine levels, then the urinary samples of pregnant women and the neonates cord blood were collected for urine iodine and TSH tests, and the relative factors were also recorded.</p><p><b>RESULTS</b>Total 1 524 urine and cord blood samples were collected from pregnant women and their new borns respectively. The median urinary iodine of pregnant women was 246.0 micro g/L, and the median TSH was 3.58 mU/L. The TSH level among seven areas and the neonatal delivery type varied significantly.</p><p><b>CONCLUSIONS</b>The neonatal cord blood TSH was influenced by several factors and could not be controlled, thus not be suitable as a iodine deficiency disorders surveillance indicator.</p>
Subject(s)
Female , Humans , Pregnancy , Delivery, Obstetric , Fetal Blood , Metabolism , Iodine , Pharmacology , Urine , Thyrotropin , BloodABSTRACT
A typical lake region with serious schistosomiasis endemic areas was selected as the study field. In the study,the 10 years (1985 - 1994) data about the agriculture sturcture and schistosomiasis prevalence was collected and analyzed. The results showed significant posi-tive correlationships among the infection rate,the total area of snail habitat and paddy field. The infection rate of human had a close relation to the infection rate of domestic animals.