Comparison of indirect haemagglutination test and elisa in relation to kato method for diagnosis of schistosoma mansoni

Schistosomiasis is a very widespread disease in the developing world and is one of the most important helminth infections in public health terms. As a behavior related disease, the risk of infection with schistosomiasis is associated to age,sex,and occupation of individuals. This study aimed to detect the reliable method for diagnosis of schistosomiasis in correlation to their sensitivity and specificity. This work was conducted on 75 patients: 46 of them were below 25 years age and 29 were above, 48 of them were males and 27 were females. They were complaining of different manifestations of intestinal schistosomiasis, subjected to history taking and clinical examinations. Stool examination was performed by Kato-Katz technique. Blood samples were withdrawn for antibodies against S. mansoni by ELISA and Indirect Haemagglutination test [IHA].S. mansoni eggs were detected among 38 [50.7%] by microscopic examination [18 of them <25 years and 20 cases >25 years old], while antibodies were recorded among 43 [57.3%] and 45 [60%] by both ULISA and IHA respectively, non significant differences were recorded between the three applied methods of examination . On comparing IHA with Kato-Katz technique as gold standard method of diagnosis, it showed 80% sensitivity and 93.3% specificity. On the other hand ELISA revealed high sensitivity and specificity 96.9% and 90.7% respectively. On comparing Kato-Katz technique to IHA it showed low sensitivity and specificity; 78.9% and 59.5% respectively .In conclusion, Kato thick smear method for diagnosis of schistosomiasis is cheap, but is time consuming and have poor specificity and sensitivity while IHA is a good diagnostic tool as it is easily applicable and specific. ELISA gave the most reliable outcome because it increased considerably the sensitivity in all stages of infection with maintenance of high specificity

Unusual localization and presentation of non-visceral hydatid cysts: review article

Echinococcosis is a major parasitic zoonosis of public health importance worldwide. This is particularly true in sheep-raising countries including Egypt. Therefore, it is very important to identify the significant risk factors of the diseases by reviewing studies done in the region in the past decade to help policy makers design appropriate control strategies

Some studies on capillaria philipinensis and its mysterious trip from philippines to Egypt [review article]

Cdpillaria philippinensis is a mysterious parasite and intestinal capillariasis is a mysterious disease. It is now more than half a century since the discovery of the first case in Philippines without answering many questions concerning the parasite's taxonomy, morphology, life cycle, diagnosis, pathology, clinical symptoms, mode of transmission as well as how it was transported to Egypt and how it started to spread and progressed in most Egyptian Governorates; particularly those of Middle Egypt. This article is a trial to overview all these aspects of the parasite