A study of Hs-CRP and lipid profile in overweight individuals.

Background: Obesity and overweight are widespread phenomena. Dyslipidaemia observed in obese people is an important risk factor for coronary heart disease. Levels of obesity have been shown to be associated with low-grade inflammation and C-reactive protein, an inflammatory marker has been associated with the presence and severity of atherosclerosis. Aims & Objective: To evaluate the Hs-CRP levels in overweight individuals with dyslipidaemia and without dyslipidaemia, and thus assess its role in detecting cardiovascular disease (CVD) in overweight individuals. Material and Methods: 120 overweight subjects were included in the study, they were divided into 2 groups- Group I which included subjects with dyslipidaemia and Group II included normolipemic subjects. BMI, Hs-CRP, Total Cholesterol, HDL-C, Triacylglycerol, LDL-C, VLDL-C, T-C/HDL-C, LDL-C/HDL-C, Glucose were estimated in both the groups and the data was statistically analyzed. Results: BMI, Hs-CRP, Total Cholesterol, Triacylglycerol, LDL-C, VLDL-C, T-C/HDL-C, LDL-C/HDL-C, Glucose were significantly higher in Group I compared to group II (p<0.05), whereas HDL-C was significantly lower in group I than group II (p<0.05). Conclusion: Hs-CRP is elevated in overweight individuals with dyslipidaemia, thus it is recommended to detect risk of CVD in them.

Pregnancy at an unusual location: a case report with review of literature

Implantation of the embryo at the site of a previous Caesarean scar is the rarest form of ectopic pregnancy, with a high risk of maternal complications. The incidence of CSP [caesarean scar Pregnancy] is estimated in a recent series as 1:2226 of all pregnancies. A delay in establishing a diagnosis and in starting treatment can result in uterine rupture, massive hemorrhage and serious maternal morbidity, and may require hysterectomy. Several options are available to treat CSP if diagnosed early, although there are no evidence-based guidelines recommended due to its rarity. The management should be tailored to the individual situations. Little is known about the future pregnancies, outcomes and recurrences after fertility-preserving treatments following CSP. We report a case of suspected CSP in a 28 year old Gravida 2, Para one, who was referred to us for the management of incomplete miscarriage. Her previous delivery was six years back and was by Cesarean section. Ultrasound examination revealed that the patient had a large anterior lower uterine segment vascular mass of 9.3x8.2x9cms, suspected to be a persistent trophoblastic tissue invading the anterior uterine wall, though a degenerating fibroid could not be ruled out. The patient underwent dilatation and curettage as she had been bleeding for more than a month and still 3HCG being positive. The procedure was also used to establish a histopathological diagnosis. A follow up MRI and Ultrasound revealed a heterogenous mass. With a strong clinical suspicion based on history and early ultrasound reports, the diagnosis of an anterior uterine wall mass probably due to penetrating trophoblastic tissue on previous caesarean scar was made. The patient has been referred for either uterine artery embolisation or a laparoscopic removal in order to preserve her fertility

Evaluation of dietary essentiality of vitamins for Penaeus monodon (Fabricius).

The effect of exclusion of individual water-soluble (thiamine, riboflavin, pyridoxine, cyanocobalamin, pantothenic acid, folic acid, niacin, biotin, choline, inositol, ascorbic acid) and fat-soluble vitamins (vit. A, D, K and E) in semi-purified diets on growth and survival of juvenile shrimp, P. monodon was studied in the laboratory for 8 weeks. Diets lacking riboflavin and vitamin K did not affect growth and survival of shrimp. However, deletion of inositol and choline resulted in poor growth. Maximum growth was observed in the control diet (C1) which was supplemented with all vitamins. Diet deficient in ascorbic acid, biotin, folic acid, niacin, thiamine and alpha-tocopherol resulted in poor appetite and poorer feed conversion efficiency. All treatments except the control (C1) resulted in histological changes in the digestive gland cells. Detachment or destruction of the epithelial cells was observed in all treatments lacking individual vitamins but more severely in the treatment without a vitamin supplement followed by inositol, choline and ascorbic acid deficient diets.