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Objective To investigate the express of collagen fibers ,NCAM11 and RUNX1 in blood-supply myocardium of myo-cardial bridge(MB) .Methods The Massion′s staining were conducted to reveal the morphology of collagen fibers in blood-supply myocardium among MB without artherosclerosis(group A) ,MB with artherosclerosis(group B) ,coronary artery disease(group C) , and non-cardiogenic instantly death(group D) .The expression level of NCAM1 and RUNX1 were detected among four groups using immunohistochemistry(IHC) and Western bolt ,respectively .Results There were a lot of collagen fibers in myocardium interstitial substance and/or heart muscle necrosis between group B and C ,but not almost collagen fibers between group A and D .The expres-sion of NCAM1 was positive in group B ,and mainly expressed on the cytoplasm and membranes of cardiac myocytes by IHC .group C was similar to results in vicinal myocardium with myocardial scar .However ,there was quite lowness or negative expression of NCAM1 in group A and D .Significant difference was found between group B as well as C and group A as well as D (P<0 .05) .The expression level of RUNX1 in blood-supply myocardium was almost like to the results of NCAM 1 .Conclusion MB with arthero-sclerosis might be lead to chronic myocardial ischemia .
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Objective To better understand pathological types of pediatric interstitial pneumonia and improve clinical diagnosis by analyzing the clinical records and pathological typing of interstitial pneumonia. Methods 70 cases of children diagnosed as interstitial pneumonia by autopsy were retrospectively analyzed. Results The number of males was more than that of females. There was a signiifcant predominance of infants less than 2 years. The clinical features include acute onset, rapid development, short duration and atypical clinical manifestations. Most patients had poor prognosis and curative effect with general therapies. Twelve cases had dubious etiology. Pathologic types of 58 cases with unclear etiology were diffuse alveolar damage type (DAD type, 38/58), desquamative interstitial pneumonia type (DIP type, 5/58), lymphoid interstitial pneumonia type (LIP type, 3/58), DAD type complicating DIP type (6/58), DAD type complicating LIP type (2/58), DAD type complicating respiratory bronchiolotitis-associated interstitial lung disease type (RB-ILD type, 3/58), DIP type complicating LIP type (1/58). Conclusions The conifrmed diagnosis rate was relatively low for pediatric interstitial pneumonia. Postmortem examination was helpful for diagnosis and improving clinical diagnosis and pathological typing.
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Objective To discuss the characteristics of knee injury in traffic accidents so as to provide an objective basis for its forensic identification.Methods Retrospective analysis was carried out on 201 cases of knee injury in traffic accidents identified by our department from 2006 to 2009.Results According to the types of knee injury,all cases were divided into bone injury group,soft tissue injury group and bone combined soft tissue injury group.Analysis of the knee joint function in the three groups revealed that there were significant differences between bone injury or bone combined soft tissues injury groups and soft tissue injury group in weight bearing including the normal bearing rate and nonbearing rate( P ＜ 0.05,respectively). ConclusionsIf patients' weight loading,walking functions as well as their gait conditions are introduced into the process of forensic identification for the knee injury in traffic accidents,the identification results will be more reasonable.
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Objective To investigate relation of IL-18 and collagen fibre(CF) with plaque stability in aorta atherosclerotic lesion.Methods Morphology and content of CF in rupture of aorta atherosclerotic group(A group),non-rupture of aorta atherosclerotic group(B group) and normal aorta group(C group) were examined by Massion's staining.Expression of IL-18 by was measured immunohistochemical staining among three groups.Results Increasing and arranging turbulence of the CF was found in tunica intima,middle layer and tunica adventitia in A and B groups.Around necrosis of atheromatous plaque,CF significantly increased and arranged turbulence,but the CF decreased or disappeared in necrosis area of atheromatous plaque in A group.The CF significantly increased,arranged turbulence and extended to SMCs in necrosis of atheromatous plaque in B group.Arranging orderliness and absence of disruption of the CF was recorded in C group.Percent age of CF content was significantly different among three groups(P
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To analyze the actuality in the education of forensic postgraduates and discuss the cultivating goal,the ability cultivation of innovation and practice.There are scientific research degree and professional degree in the forensic medicine.
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0.05).But there were obvious differences between each electrically injured groups and each burned groups(P