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Rev. Fac. Cienc. Méd. (Quito) ; 43(2): 175-182, dic. 2018.
Article in Spanish | LILACS | ID: biblio-1361824

ABSTRACT

La tuberculosis causada por la bacteria Mycobacterium tuberculosis, se encuentra entre las 10 primeras causas de mortalidad a nivel mundial; la presentación extrapulmonar se produce por siembra vía hematógena o linfática desde un foco primario, correspondiendo a la afectación de sistema nervioso central el 5% de infecciones por TB y se presenta con menor frecuencia en personas inmunocompetentes. Las formas de tuberculosis de SNC son meningitis, tuberculosis espinal y tuberculomas que corresponden al 1% de infecciones por TB. El tratamiento se basa en la terapia antifímica, reservando el manejo neuroquirúrgico para puntuales indicaciones como deterioro neurológico, hidrocefalia o mala respuesta al tratamiento farmacológico.


Tuberculosis, caused by the Mycobacterium tuberculosis bacteria, is among the top 10 cau-ses of mortality worldwide; The extrapulmonary presentation is produced by hematogenous or lymphatic seeding from a primary focus, 5% of TB infections corresponding to central nervous system involvement and occurs less frequently in immunocompetent people. The forms of CNS tuberculosis are meningitis, spinal tuberculosis and tuberculomas that corres- pond to 1% of TB infections. The treatment is based on antifungal therapy, reserving neurosurgical management for specific indications such as neurodeterioration, hydrocephalus or poor response to pharmacological treatment


Subject(s)
Humans , Female , Pregnancy , Adult , Tuberculoma, Intracranial , Tuberculosis, Central Nervous System , Immunocompetence , Tuberculoma, Intracranial/surgery , Tuberculoma, Intracranial/diagnosis , Tuberculoma, Intracranial/drug therapy , Tuberculoma, Intracranial/diagnostic imaging , Diagnosis, Differential , Neurologic Manifestations
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