ABSTRACT
Objective To analyze the relationship between clinical characteristics and prognosis of patients with acute herbicide poisoning marked diquat.Methods A multi-center,retrospective clinical study of patients with acute diquat poisoning admitted into Emergency Department was conducted from June 2015 to August 2018 in 8 hospitals in Jiangsu Province.Results A total of 43 patients (22 males and 21 females) were collected and the peak age of poisoning ranged 20-39 years old.The only route of poisoning was ingestion.Among these cases,suicide was the most common cause ofpoisoningaccounting for 90.70％.In emergency treatment,the constituent ratios of gastric lavage,hemoperfusion and glucocorticoid were 87.50％,72.50％ and 42.50％,respectively.The total mortality increased to 60.00％ after follow-up,while the in-hospital mortality was 18.60％.The mortality of patients with toxic dose ＜ 50 mL was 11.11％.Conclusions The incidence of acute herbicide poisoning with "diquat" as commercial component is gradually increasing.At present,the mortality is very high.Ingestion poisoning dose is the key factor affecting prognosis,and the prognosis of patients with oral dose ＞ 50 mL is poor.
ABSTRACT
Objective@#To analyze the relationship between clinical characteristics and prognosis of patients with acute herbicide poisoning marked diquat.@*Methods@#A multi-center, retrospective clinical study of patients with acute diquat poisoning admitted into Emergency Department was conducted from June 2015 to August 2018 in 8 hospitals in Jiangsu Province.@*Results@#A total of 43 patients (22 males and 21 females) were collected and the peak age of poisoning ranged 20-39 years old. The only route of poisoning was ingestion. Among these cases, suicide was the most common cause of poisoningaccounting for 90.70%. In emergency treatment, the constituent ratios of gastric lavage, hemoperfusion and glucocorticoid were 87.50%, 72.50% and 42.50%, respectively. The total mortality increased to 60.00% after follow-up, while the in-hospital mortality was 18.60%. The mortality of patients with toxic dose < 50 mL was 11.11%.@*Conclusions@#The incidence of acute herbicide poisoning with "diquat" as commercial component is gradually increasing. At present, the mortality is very high. Ingestion poisoning dose is the key factor affecting prognosis, and the prognosis of patients with oral dose > 50 mL is poor.