ABSTRACT
Objective To observe the effect of rhBMP-2 (bone Guide) in the treatment of femoral neck fracture. Methods In our hospital from January 2016 to May 2017, 86 patients with femoral neck fracture were randomly divided into observation group and control group, 43 cases in each group. The observation group was treated with closed reduction and cannulated screw fixation compared with cannulated screw tunnel rhBMP-2 (recombinant human bone morphogenetic protein-2) implantation for the treatment of the control group. Observe the curative effect and adverse reaction. Results The observation group's bone healing rate and hip joint function score higher than the control group, and intraoperative blood loss and postoperative bed time, bed time, fracture healing time, time, the incidence of femoral head necrosis, incidence of complications were lower than those in control group. The difference was significant (P＜0.05); there was no significant difference between the two group operation time (P＞0.05). Conclusion The treatment of femoral neck fracture with bone guide and percutaneous screw placement has good therapeutic effect, and it can prompt patients to recover as early as possible and reduce the occurrence of osteonecrosis of the femoral head.
ABSTRACT
BACKGROUND:Studies have shown that anterolateral approach for repairing the hip joint capsule has great effects on dislocation after hip replacement, but it remains unclear at present. OBJECTIVE: To study the impact of anterolateral approach for repairing the hip joint capsule on dislocation after artificial hip joint replacement. METHODS: 480 patients, who received artificial hip joint replacement in the First People’s Hospital of Qinzhou from January 2010 to January 2014, were enroled in this study. They were divided into the control group (January 2010 to January 2012) and the observation group (February 2012 to January 2014) according to the order of their admission, each of 240 cases. The control group was subdivided into the total hip replacement group (A1 group) and the femoral head replacement group (A2 group), each of 120 cases; and the observation group was also subdivided into the total hip replacement group (B1group) and the femoral head replacement group (B2 group), each of 120 cases. A1group and A2 group were subjected to artificial hip joint replacementvia anterolateral approach. B1 group and B2 group were subjected to artificial hip joint replacementvia anterolateral approach and the repair of the joint capsule. The postoperative early dislocation rate was analyzed in patients of A1 group and B1 group. Postoperative early dislocation rate was analyzed in patients of A2 group and B2 group. RESULTS AND CONCLUSION: The rate of early postoperative dislocation was 6.7% in A1 group, and 0.8% in the B1 group. The rate of early postoperative dislocation was significantly higher in the A1group than in the B1 group (P 0.05). Results showed that anterolateral approach in repairing the hip joint capsule can effectively reduce the incidence of postoperative dislocation after the total hip replacement, but does not obviously impact postoperative dislocation.