ABSTRACT
@#【Objective】To explore colonoscopy adherence and related factors among preliminary screened-positive population in Guangzhou. 【Methods】This study was a part of the Guangzhou Community-based Colorectal Cancer Screening Program. We retrospectively analyzed the 1-year follow-up data of population aged 50~74 years old and positive in preliminary colorectal cancer screening in 2015. Kaplan- Meier method was used to describe the respond time to colonoscopy examination. Cox proportional hazard model was performed to identify factors associated with colonoscopy adherence. The effect of studied factors on colonoscopy adherence was reported according to hazard ratio（HR）.【Results】 A total of 18 604 preliminary screened-positive residents were included ，among whom 4 014 completed colonoscopy examination within one year，with a colonoscopy adherence of 21.6% . Colorectal lesions were found in 2 012 cases （50.1%），of which 96（2.4%）were colorectal cancers. The adherence of 1 month，3 months and 6 months were 9.7% ，15.8% ，and 18.6% respectively. Multivariate Cox regression analysis showed that those who were female ，in older age ， unmarried/widowed/divorced，without health insurance，and had a history of chronic cholecystitis or cholecystectomy were less likely to undergo colonoscopy；while those who were fecal occult blood test- positive，had colonoscopy preferential policies，worked in government or public institution，had medical insurance for urban workers，had a history of chronic diarrhea，a history of chronic constipation，a history of mucous and/or blood stool，and a history of bad life incidents were more likely to undergo colonoscopy. 【Conclusions】 This study suggested that the colonoscopy adherence of preliminary screened- positive population in Guangzhou was low and such low adherence was associated with different factors. Community health workers should timely track the completion of colonoscopy of preliminary screened-positive residents ， and take targeted measures to promote colonoscopy adherence.