Penicillum marneffi infection presenting as lump abdomen.

Penicillum Marneffi is the third leading opportunistic pathogen in HIV endemic areas. We report a case, with a rare clinical presentation as lump abdomen with newly diagnosed HIV -1 antibody reactive status. A diagnosis was made by endoscopic biopsy of growth in second part of duodenum which on histopathology and culture detected Penicillum Marneffi. He was treated with intravenous amphotericin B for 2 weeks followed by oral itraconazole. This case is reported for its unusual presentation to sensitize clinicians to consider this as an etiology in patients in HIV endemic areas who present as lump abdomen.