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Saude e pesqui. (Impr.) ; 8(3): 461-467, set-dez 2015.
Article in Portuguese | LILACS | ID: biblio-831973

ABSTRACT

Tagetes patula L. (Asteraceae), popularmente conhecida como cravo de defunto ou cravo francês, é utilizada na medicina popular como antisséptica, depurativa do sangue e repelente de insetos. O presente estudo avaliou a atividade antisséptica de sabonete líquido contendo extrato glicólico de T. patula 7,5% (p/v). O extrato glicólico foi obtido por turbo-extração utilizando propilenoglicol e etanol (7:3; v/v) a 10 % (p/v). A avaliação fitoquímica preliminar da droga vegetal indicou a presença de compostos fenólicos e teor de flavonoides de 5,73% ± 0,19 (CV = 3,33%). No teste para avaliação da atividade antimicrobiana houve a inibição do crescimento de Staphylococcus aureus na concentração de avaliada.


Tagetes patula L. (Asteraceae), or French marigold, known in Brazil as cravo-de-defunto, is used in folk medicine as antiseptic, blood thinner and insect repellent. Current study analyzes the antiseptic activity of the liquid soap with the glycolic extract of T.patula 7.5% (p/v). Glycolic extract was obtained by turbo-extraction with propylenoglycol and ethanol (7:3; v/v) 10 % (p/v). Preliminary photochemical evaluation of the vegetal drug showed phenolic compounds and flavonoid rates at 5.73% ± 0.19 (CV = 3.33%). When the pharmaceutical formulation was evaluated for antimicrobial activity, growth inhibition of Staphylococcus aureus occurred at the assessed concentration.


Subject(s)
Flavonoids , Anti-Infective Agents, Local , Pharmaceutical Preparations , Phenolic Compounds , Phytochemicals
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