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1.
Acta méd. peru ; 28(2): 79-81, abr.-jun. 2011. tab
Article in Spanish | LILACS, LIPECS | ID: lil-605403

ABSTRACT

Hasta el 10% de pacientes con Lupus Eritematoso sistémico tienen la artropatía similar a Artritis Reumatoide, denominado ôRuphusõ. En estos pacientes prevalecen los signos y síntomas de Artritis reumatoide y el compromiso renal está asociado con Lupus. Objetivo: Describir las características clínicas y hallazgos histopatológicos renales en pacientes con Ruphus. Materiales y métodos: Reporte de Casos detectados en forma retrospectiva en el Hospital Nacional Arzobispo Loayza, entre los años 2003 al 2009 y sus biopsias renales. Resultados: Hubo 7 pacientes con ruphus, la mediana de edad fue 40 años, una mediana de tiempo de evolución de 2 años. Los hallazgos histopatológicos renales relevantes fueron Glomerulonefritis lúpica tipo IV en 5 pacientes; proteinuria entre 288 a 2560 mg/24 horas y títulos de Factor Reumatoide entre 14 a 34,6 UI/L. Conclusiones: Los pacientes reportados a diferencia de la literatura fueron de mayor edad, con compromiso renal moderado a severo relacionado a Lupus.


Up to 10% of patients with Systemic Lupus Erythematosus have a joint condition similar to that of rheumatoid arthritis, which is called ôRhupusõ. These patients predominantly have signs and symptoms of rheumatoid arthritis and kidney damage associated with Lupus. Objectives: To describe the clinical characteristics and the renal histopathological findings in patients with rhupus. Materials and methods: Retrospective review of case reports and kidney biopsies from patients seen from 2003 to 2009 in Arzobispo Loayza National Hospital. Results: There were 7 patients with rhupus; their median age was 40 years, the median time of disease progression was 2 years. Most relevant renal histopathological findings were type IV glomerulonephritis in 5 patients; proteinuria between 288 to 2560 mg/24 hours and rheumatoid factor titers between14 to 34.6 UI/L were also found. Conclusions: Patients were older compared to others previously reported previously in the literature. Lupus-related renal damage was moderateto severe.


Subject(s)
Humans , Male , Female , Young Adult , Arthritis, Rheumatoid/diagnosis , Lupus Nephritis/diagnosis , Lupus Nephritis/pathology , Retrospective Studies
2.
Rev. Soc. Peru. Med. Interna ; 23(1): 24-27, ene.-mar. 2010. ilus
Article in Spanish | LILACS, LIPECS | ID: lil-564634

ABSTRACT

Se presenta el caso de una mujer de 31 años, con diagnóstico de infección por el virus de inmunodeficiencia humana (VIH) por seis años y sin tratamiento antirretroviral. Ingresa al Servicio de Emergencia con un cuadro de insuficiencia respiratoria aguda severa y recibió tratamiento antituberculoso y cotrimoxazol para Pneumocystis jiroveci; con evolución desfavorable que terminó en muerte a las 48 horas del ingreso. El hallazgo anatomopatológico del parénquima pulmonar reveló la presencia de Citomegalovirus y Cryptococcus sp.


A 31 year-old woman, with a six year history of HIV infection and without treatment, entered to the emergency ward with acute and severe respiratory distress for which she received antituberculous treatment and cotrimoxazole for Pneumocystis jiroveci. After a declining condition, the patient died at 48 hours after admission. The histopathological study of the lung parenchyma revealed Cytomegalovirus and Cryptococcus sp. infections.


Subject(s)
Humans , Adult , Female , Cytomegalovirus , Cryptococcus , HIV Infections , Pneumonia
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