ABSTRACT
OBJECTIVE: The aim of this study was to evaluate whether the presence of phIGFBP-1 in cervical secretion of patients with symptoms suggestive of preterm labor predicts preterm delivery. METHODS: Patients who were examined at the Department of Obstetrics and Gynecology, Daegu Fatima hospital between 24 weeks' and 34 weeks' gestation with intact membrane, no prior tocolysis, symptoms suggestive of preterm labor, and cervical dilatation or=10 microgram/L. Tocolysis and corticosteroids were used when clinically indicated after specimen collection. RESULTS: phIGFBP-1 was detected in 21 patients among 50 patients analysis. Compared with patients who had negative results, patients who had positive results for phIGFBP-1 were more likely to deliver before 37 weeks (p<0.001), before 34 weeks (p=0.008) and within 7 days (p<0.001). Sensitivity, specificity, positive predictive value and negative predictive value were 77.3%, 85.7%, 81.0%, and 8.28%. Patients with positive results were also treated more with tocolysis and corticosteroids use than patients with negative results. Gestational age at delivery (p<0.001) and birthweight (p<0.001) were lower for patients with positive results. CONCLUSION: In a population of patients with symptoms, the presence of phIGFBP-1 in cervical secretions defines a subgroup at increased risk for preterm delivery.
Subject(s)
Female , Humans , Pregnancy , Adrenal Cortex Hormones , Gestational Age , Gynecology , Labor Stage, First , Membranes , Obstetric Labor, Premature , Obstetrics , Sensitivity and Specificity , Specimen Handling , TocolysisABSTRACT
Aplastic anemia in pregnancy is an extremely rare condition with high maternal morbidity and mortality rates. Prognosis is poorer when aplastic anemia is complicated during pregnancy and many such patients have an unsuccessful pregnancy outcome. The relationship between aplastic anemia and pregnancy remains uncertain. Intensive hematological support remains the mainstay of therapy and a successful obstetric outcome can be best accomplished with the close clinical collaboration of the hematologist and the obstetrician. We report here a case of a 24-year-old woman with aplastic anemia, she experienced two consecutive vaginal deliveries. We present it with brief review of literature.
Subject(s)
Female , Humans , Pregnancy , Young Adult , Anemia, Aplastic , Cooperative Behavior , Mortality , Pancytopenia , Pregnancy Outcome , PrognosisABSTRACT
Malignant mixed mullerian tumor (MMMT) of the uterus are uncommon tumor and highly malignant containing epithelial and stromal components which is classified as homologous or heterologous based on the nature of sarcomatous component. It is highly malignant and the prognosis is poor due to frequent metastasis and recurrence, which most patients were associated with postmenopausal status. We experienced one case of malignant mixed mullerian tumor of uterus with neuroendocrine differenciation. So we report this case with a brief review of literature.
Subject(s)
Humans , Neoplasm Metastasis , Prognosis , Recurrence , UterusABSTRACT
Subamniotic hematoms are rare placental pathological lesions resulting from the rupture of chorionic vessels near the cord insertion. Most subamniotic hematomas are found after birth and result from excessive traction on the umbilical cord at delivery. The development of these lesions has been rarely reported in utero. A case of a subamniotic hematoma was diagnosed by ultrasound at 7(+5) weeks of gestation. We describe the ultrasound features of a subamniotic hematoma and the differential diagnosis.
Subject(s)
Pregnancy , Chorion , Diagnosis, Differential , Hematoma , Parturition , Placenta , Prenatal Diagnosis , Rupture , Traction , Ultrasonography , Umbilical CordABSTRACT
Struma ovarii consists of thyroid tissue derived from germ cells in a mature teratoma and which all or a large part is composed of thyroid tissue. Malignant transformation and clinically evident metastatic disease are very rare. The rarity of malignant struma ovarii renders evaluation of treatment modality difficult. There is evidence that these tumors behave like their thyroid counter parts, and cytoreductive surgery followed by ablation with radioactive iodine has been advocated. We have experienced a case of malignant struma ovarii. In this report, we present clinical and pathological findings of a case of malignant struma ovarii of 51-year-old patient with a review of the concerned literatures.
Subject(s)
Humans , Middle Aged , Germ Cells , Iodine , Struma Ovarii , Teratoma , Thyroid GlandABSTRACT
Meconium peritonitis is the chemical inflammation or foreign body reaction of peritoneum resulted from the prenatal bowel perforation associated with or without obstructive lesion during late intrauterine or early neonatal periods. Prenatal ultrasonographic findings of meconium peritonitis are intraperitoneal calcification, ascites, and pseudocyst. These provides the preparation for proper management which should reduce mortality and morbidity of neonate. We have experienced a case of meconium peritonitis in utero diagnosed by prenatal ultrasonography and present this case with a brief review of literatures.
Subject(s)
Humans , Infant, Newborn , Ascites , Foreign-Body Reaction , Inflammation , Meconium , Mortality , Peritoneum , Peritonitis , Ultrasonography, PrenatalABSTRACT
Actinomycosis is difficult to diagnose preoperatively because of non-specific clinical feature. We usually have excessively invasive treatment for actinomycosis. So, we must rule out actinomycosis in the case of patients with a complaint of lower abdominal pain with a long time IUD inserted state and laboratory findings suggestive of inflammation. We experienced two cases of pelvic actinomycosis associated with IUD and report these cases with a brief review of literatures.
Subject(s)
Humans , Abdominal Pain , Actinomycosis , Inflammation , Intrauterine DevicesABSTRACT
Ectopic pregnancy developing in the previous cesarean section scar is the rarest forms of ectopic pregnancy and very dangerous because of the risk of uterine rupture and hemorrhage. Hysterectomy was usually done in the management but, conservative treatment is desirable for young women who want to maintain her fertility. We present three cases of ectopic pregnancy developing in the previous cesarean section scar in which successfully treated with conservative management.
Subject(s)
Female , Humans , Pregnancy , Cesarean Section , Cicatrix , Fertility , Hemorrhage , Hysterectomy , Pregnancy, Ectopic , Uterine RuptureABSTRACT
OBJECTIVE: The aim of this study is to review 6 years' experience of peritoneal inclusion cysts at our hospital. METHODS: A retrospective study of 13 cases of peritoneal inclusion cysts between Jan. 1, 1996 and Dec. 31, 2001 was carried out and then clinical feature, radiologic finding, and treatment method were compared with previous reports. RESULTS: Most of patients were premenopausal. Chief complaints were lower abdominal pain or palpable abdominal mass, and so forth. The majority of patients had history of lapalotomy. Peritoneal inclusion cyst was diagnosed by ultrasonogrphy and CT. Most specific finding is that normal ovary is seen in the cysts. In the past, operation was the main treatment method. Recently sclerotherapy was introduced and available. CONCLUSION: Because peritoneal inclusion cyst is benign and uncommon disease, it had not been interesting part. So, preoperative diagnosis rate was low and surgical resection was main treatment method. Preoperative diagnosis rate has been higher after it's clinical feature and specific radiologic findings were reported. Recently, conservative treatment may substitute for operation.
Subject(s)
Female , Humans , Abdominal Pain , Diagnosis , Ovary , Retrospective Studies , Sclerotherapy , UltrasonographyABSTRACT
A 26-year-old woman presented at 28 weeks' gestation with intracranial hemorrhage, stuporous mentalilty. The pregnancy was maintained with supportive care. At 35+1 weeks' gestation, a 2560 gm, healthy male baby was delivered by means of cesarean section. Maintaining adequate nutritional status is vital in achieving appropriate fetal growth and development. Maternal malnutrition may have an adverse effect on the fetus and neonate, with deleterious effect on birth weight and brain development. When the mother is unconcious, fetal well-being should be assessed by serial biophysical profile scoring. There is no neurosurgical contraindication to vaginal delivery if patient is of good neurologic grade. Nevertheless, cesarean section may be preferable if the patient is in poor neurologic condition.
Subject(s)
Adult , Female , Humans , Infant, Newborn , Male , Pregnancy , Birth Weight , Brain , Cesarean Section , Fetal Development , Fetus , Intracranial Hemorrhages , Malnutrition , Mothers , Nutritional Status , StuporABSTRACT
The development of primary squamous cell carcinoma in the endometrium is extremely rare. In 1928 Fluhmann proposed three criteria to establish the diagnosis: (1) no coexisting endometrial adenocarcinoma, (2) no connection between the endometrial tumor and the squamous epithelium of the cervix and (3) no squamous cell carcinoma of the cervix present. More recently, the World Health Organization (WHO) updated Fluhmann's criteria by adding that the tumor must contain clear evidence of squamous differentiation, such as the presence of intercellular bridges and/or keratin. We have experienced a case of primary endometrial squamous cell carcinoma which fulfills Fluhmann's criteria and WHO's. In this report, we present the clinical and pathological findings of a case of a primary endometrial squamous cell carcinoma of a 62-year-old patient with a review of the concerned literatures.
Subject(s)
Female , Humans , Middle Aged , Adenocarcinoma , Carcinoma, Squamous Cell , Cervix Uteri , Diagnosis , Endometrium , Epithelium , World Health OrganizationABSTRACT
Acardiac twinning affects 1 in 100 monozygotic twin pregnancies and 1 in 35,000 pregnancies overall. This condition is characterized by the absence or rudimentary development of fetal heart, and associated with various anomaly. The presence of an acardiac twin requires the normal (or "pump") twin to provide circulation for itself, as well as the acardiac sibling. The acardiac malformations are uniformly fatal in the affected twin, and mortality in the co-twin is as high as 55%. The principal perinatal problems associated with acardiac twinning are pump-twin congestive heart failure, maternal hydramnios, and preterm delivery. We recently experienced a case of acardius anceps associated with a normal male infant, so present with a brief review of the literature.
Subject(s)
Humans , Infant , Male , Pregnancy , Fetal Heart , Heart Failure , Mortality , Polyhydramnios , Siblings , Twins, MonozygoticABSTRACT
Fetal bilateral renal agenesis is a lethal congenital anomaly. An early and reliable prenatal diagnosis is extremely important as it may offer options for pregnancy termination as early as possible. The criteria for the ultrasonographic diagnosis of bilateral renal agenesis are severe oligohydramnios, nonvisualization of the bladder, and the empty renal fossa. However, severe oligohydramnios makes it difficult to diagnose the disease because of poor sonographic resolution. We present two cases of bilateral renal agenesis, one is diagnosed by ultrasonography after amnioinfusion at 24 weeks gestation, the other is diagnosed postnatally after term delivery.
Subject(s)
Female , Pregnancy , Diagnosis , Oligohydramnios , Prenatal Diagnosis , Ultrasonography , Urinary BladderABSTRACT
No abstract available.