1.
Indian J Pathol Microbiol
; 1998 Oct; 41(4): 423-6
Article
in English
| IMSEAR
| ID: sea-75835
ABSTRACT
Beta-Thalassemia is prevalent in a high frequency of 5-15% in selected geographical areas and ethnic communities. There is need to screen large populations for the heterozygotes of beta-Thalassemia. We have evaluated NESTROFT (Naked eye single tube red cell osmotic fragility test) with 0.36% buffered saline in this study. Of the population screened, 42 cases were positive with NESTROFT, of which 40 were positive with the confirmatory test for beta-Thalassemia. This implies a positive predictive value and specificity of 100%, negative predictive value of 83.3% and sensitivity of 95.2%.
Subject(s)
Adolescent , Adult , Aged , Child , Child, Preschool , Erythrocytes/metabolism , Female , Genetic Carrier Screening/methods , Humans , Infant , Longitudinal Studies , Male , Middle Aged , Sensitivity and Specificity , beta-Thalassemia/diagnosis
2.
Indian J Pathol Microbiol
; 1998 Apr; 41(2): 173-92
Article
in English
| IMSEAR
| ID: sea-73496