ABSTRACT
Terminalia bellerica Roxb. (Family: Combretaceae) has been valued in Indian system of medicine for treatment of wide range of diseases and reported to have antioxidant properties. In the present study, the free radical scavenging activity and antioxidant potential of acetone extract/fractions of its fruit was investigated using in vitro assays, including scavenging ability against 2,2′-diphenyl-2-picrylhydrazyl (DPPH), β-carotene bleaching inhibition, reducing power and chelating ability on Fe2+ ions. The fruit powder was extracted at room temperature with different solvents in the order of increasing and decreasing polarity to obtain crude acetone extract which was further partitioned with ethyl acetate and water (1:1). It was found that ethyl acetate fraction was more effective than crude acetone extract in all antioxidant assays, except chelating power which was highest in water fraction. Maximum antioxidant activities (expressed as EC50 values) observed were 14.56 μg/ml, 27.81 μg/ml and 67.8 μg/ml in DPPH, β-carotene bleaching and reducing power assays, respectively. The antioxidant potential was compared with known antioxidant (butylated hydroxyl toluene) and correlated with total phenolic and flavonoid content in crude extract and fractions. Fractions rich in polyphenolic content were more effective than the crude extract.
Subject(s)
Acetone/chemistry , Biphenyl Compounds/metabolism , Chemical Fractionation , Flavonoids/analysis , Free Radical Scavengers/chemistry , Free Radical Scavengers/isolation & purification , Free Radical Scavengers/metabolism , Free Radical Scavengers/pharmacology , Fruit/chemistry , Phenol/analysis , Picrates/metabolism , Plant Extracts/chemistry , Plant Extracts/isolation & purification , Plant Extracts/metabolism , Plant Extracts/pharmacology , Terminalia/chemistryABSTRACT
Dentigerous cysts are the most common bony lesions of the jaws in children. It is one of the most prevalent types of odontogenic cysts associated with an erupted or developing tooth, particularly the mandibular third molars; the other teeth that are commonly affected are, in order of frequency, the maxillary canines, the maxillary third molars and, rarely, the central incisor. Radiographically, the cyst appears as ovoid well-demarcated unilocular radiolucency with a sclerotic border. The present case report describes the surgical enucleation of a dentigerous cyst involving the permanent maxillary right central incisor; the surgery was followed by oral rehabilitation. Careful evaluation of the history and the clinical and radiographical findings help clinicians to correctly diagnose the condition, identify the etiological factors, and administer the appropriate treatment.
Subject(s)
Child , Dental Fistula/diagnosis , Dentigerous Cyst/diagnosis , Diagnosis, Differential , Follow-Up Studies , Humans , Incisor/pathology , Male , Maxillary Diseases/diagnosisABSTRACT
A rare case of two root canals in all mandibular anterior teeth is presented. The patient initially reported for the treatment of mandibular right central and lateral incisors. However, radiographic evaluation revealed variant root canal and apical foramen patterns.
ABSTRACT
The management of two unusual cases of dens invaginatus and talon cusp is presented. The first concerns talon cusp in maxillary primary and permanent lateral incisors, a supplemental tooth with dens invaginatus hampering eruption of the permanent incisors. The other present with bizarre crown morphology of a lateral incisor with talon cusp, dens invaginatus and a palatal accessory cusp-like structure. Early diagnosis and management are important to avoid complications.
Subject(s)
Child , Dens in Dente/complications , Female , Humans , Incisor/abnormalities , Male , Malocclusion/etiology , Occlusal Adjustment , Orthodontics, Corrective , Tooth Crown/abnormalities , Tooth Extraction , Tooth, Supernumerary/complications , Tooth, Unerupted/etiologyABSTRACT
A case with a open apex and a large periapical lesion in a 10 year old boy is presented. The lesion formed as a result of necrosis from trauma to a maxillary right central incisor 1 year ago. Apical closure and complete healing of periapical lesion was observed after non-surgical endodontic treatment using calcium hydroxide paste. This report suggests that even large periapical lesions could respond favourably to non-surgical treatment.
Subject(s)
Calcium Hydroxide , Child , Dental Fistula/epidemiology , Dental Pulp Necrosis/complications , Humans , Incisor , Male , Maxilla , Periapical Diseases/etiology , Root Canal Irrigants , Root Canal Therapy , Tooth Apex/growth & developmentABSTRACT
The management of two cases of hypertaurodontism, is presented. The first case shows this uncommon dental anomaly in all the four permanent first molars. The second case is concerned with endodontic management of a hypertaurodontic mandibular second premolar. The authors wish to highlight the importance of careful radiographic examination in diagnosing this rare dental anomaly in view of the difficulties encountered in performing endodontic treatment.
Subject(s)
Bicuspid/abnormalities , Child , Dental Pulp Capping , Dental Pulp Cavity/abnormalities , Follow-Up Studies , Humans , Male , Molar/abnormalities , Odontometry , Radiography, Panoramic , Root Canal Therapy , Tooth Root/abnormalitiesABSTRACT
Oral administration of an algal mutant C. vulgaris E-25, 1 hr before or immediately after exposure to sublethal gamma-rays increased the number of endogenous spleen colony forming units (E-CFU). The magnitude of radioprotection was dependent on both, the dose of C. vulgaris fed and the time of administration. An optimal E-CFU was observed when 500 mg/kg body wt. of C. vulgaris was fed 1 hr before or immediately after irradiation. Significant recovery was observed in the number of bone marrow cells and the spleen weight. LD50/30 for Chlorella pre- and post-treated mice were 8.66 and 9.0 Gy, respectively compared to the control value of 7.8 Gy. The dose reduction factor (DRF) was 1.11 and 1.15 for pre-treated and post-treated mice respectively.