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1.
Indian J Pathol Microbiol ; 2012 Oct-Dec 55(4): 535-537
Article in English | IMSEAR | ID: sea-145655

ABSTRACT

Cerebral ganglioneuroblastoma is an embryonal tumor of the central nervous system, which has been rarely encountered into the spinal cord. The standard treatment for ganglioneuroblastoma is complete surgical excision. A 15-year old boy was presented with cord compression. Magnetic resonance imaging revealed an intradural and intramedullar enhancing lesion over T2 spine. A histomorphological diagnosis was made in the presence of immature small round cells admixed with a good number of ganglion cells. The morphological diagnosis was verified by immunohistochemistry. This is the first reported case of compressive myelopathy in the thoracic region of the spine.


Subject(s)
Adolescent , Ganglioneuroblastoma/diagnosis , Ganglioneuroblastoma/epidemiology , Ganglioneuroblastoma/surgery , Humans , Male , Spinal Cord Neoplasms/diagnosis , Spinal Cord Neoplasms/epidemiology , Spinal Cord Neoplasms/surgery , Thoracic Vertebrae/pathology
2.
Indian J Pathol Microbiol ; 2006 Jul; 49(3): 392-3
Article in English | IMSEAR | ID: sea-72762

ABSTRACT

Endovascular papillary angioendothelioma (EPA) is a rare vascular tumor of low grade malignancy, encountered primarily in children. However some cases have also been reported in adults. A sixty year old female with EPA is described here. She presented with a swelling in the neck. Total surgical excision was performed. Histomorphology revealed anastomosing lymphatic channels showing intraluminal papillary fronds with hyaline vascular cores and hobnailing of endothelial cells. A diagnosis of EPA was made based on this picture. This tumor is recurrent and nodal metastasis has been reported in some cases.


Subject(s)
Diagnosis, Differential , Female , Head and Neck Neoplasms/diagnosis , Hemangioendothelioma/diagnosis , Humans , Middle Aged , Neck/pathology
3.
Indian J Pathol Microbiol ; 2005 Jul; 48(3): 375-6
Article in English | IMSEAR | ID: sea-74377

ABSTRACT

Haemangioblastoma is a rare benign vascular tumor commonly seen in the cerebellum. There is a striking histologic similarity between cellular variant of haemangioblastoma and metastatic renal cell carcinoma. We present a case of haemangioblastoma in a 32-year-old male. Histology revealed a highly vascular tumor composed of clear cells in a lobular arrangement.


Subject(s)
Adult , Carcinoma, Renal Cell/diagnosis , Cerebellar Neoplasms/diagnosis , Cerebellum/pathology , Diagnosis, Differential , Hemangioblastoma/diagnosis , Humans , Male
4.
Indian J Pathol Microbiol ; 2005 Apr; 48(2): 221-3
Article in English | IMSEAR | ID: sea-75290

ABSTRACT

Plasma cell leukemia (PCL) is a rare type of plasma cell dyscrasia. It is diagnosed when circulating plasma cells (PC) are more than 20%. We present a case of PCL in a 62-year-old female. Peripheral smear revealed more than 80% atypical vacuolated plasma cells (Mott cells) almost mimicking Burkitt cells of Acute Lymphoid Leukemia-L3 (ALL-L3). Bone marrow aspirate revealed few mature myeloma cells for which a diagnosis of PCL was thought of. Serum electrophoresis showed a positive M-band and X-ray revealed lytic lesions over femur & pelvic bones. A final diagnosis of PCL was given.


Subject(s)
Bone Marrow/pathology , Diagnosis, Differential , Female , Humans , Leukemia, Plasma Cell/diagnosis , Middle Aged , Plasma Cells/cytology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis
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