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Objective To understand the death prevalence of cardiovascular and cerebrovascular diseases and the life expectancy of premature death caused by them in Suzhou, and to provide data basis for the health administrative department to formulate the prevention and control policies of cardiovascular and cerebrovascular diseases. Methods Based on the death data of ischemic heart disease and stroke of residents in Suzhou from 2011 to 2020, the death prevalence of cardiovascular and cerebrovascular diseases during the past decade was calculated. The years of life lost (YLLs), years of life lost per thousand (YLL rate) and annual percentage of change (APC) caused by ischemic heart disease and stroke were calculated. The YLLs and YLL rates of different age groups and different genders were also calculated. Results From 2011 to 2020, the average annual mortality rate of ischemic heart disease in Suzhou was 45.61/100 000, and the mortality rate showed an upward trend in the past decade. The average annual mortality rate of stroke was 174.23/100 000, with a trend of decreasing first and then increasing in the past decade. From 2011 to 2020, the disease burden caused by ischemic heart disease in Suzhou totaled 359,153.97 YLLs, with a YLL rate of 6.77 person years per 1000 people, and an APC of 2.05%. The YLLs caused by stroke death were 1 269,193.8 person years, the YLL rate was 23.91 person years per thousand, and the APC was 1.35%. Conclusion From 2011 to 2020, the prevention and treatment of cardiovascular and cerebrovascular diseases in Suzhou has achieved certain results, but ischemic heart disease and stroke are still important causes affecting the health of people and causing death and life loss of the elderly in Suzhou. The prevention and treatment of cardiovascular and cerebrovascular diseases still has a long way to go, and it is necessary to continue strengthening the screening, monitoring and intervention work.
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Objective@#To analyze the mental health status of clinical medical standardized training graduate students (referred to as: graduate students).@*Methods@#Through the online questionnaire, the Symptom Checklist (SCL-90), adult psychological stress scale, and occupational satisfaction were used to compare the first affiliated hospital of Bengbu Medical College from January 2018 to June 2019. 498 graduate students of the Department of Neurology, the Second Affiliated Hospital of Bengbu Medical College and the Third People’s Hospital of Bengbu City, and 420 medical non-regular graduate students conducted a survey on the status of psychological stress and statistical analysis of the results.@*Results@#The psychological stress of graduate students(40.28±10.43) was significantly higher than that of non-regular graduate students(36.95±5.13)， and the psychological stress of male students(41.75±11.17) in medical disciplines was significantly higher than that of female students(38.81±9.43). The difference was statistically significant(t=2.44，3.16，P<0.05); There was no significant difference in the occupational satisfaction scores between the two groups(t=1.94，1.27，P>0.05). The SCL-90 factor evaluation results of graduate students were significantly higher than those of non-regular graduate students. The scores of depression, anxiety and terror factor of male students in the graduate students were significantly higher than those of girls, and the differences were statistically significant(P<0.05).@*Conclusion@#The mental health status of postgraduates in clinical medicine is generally poor, and the mental health of boys is worse than that of girls.
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Objective: To study the relationship between the age of menarche and the near-term/long-term obesity in adult women. Methods: We analyzed the baseline data of 30 895 women with complete data on menarche and body measurement that was from the China Kadoorie Biobank (CKB) study from 2004 to 2008. The age of menarche was divided into three groups: ≤12, 13-16 and ≥17 years old. Prematurity was set at age ≤12 years. Multivariate logistic regression was used to analyze the effects of menarche age on the near/long-term obesity in female adults. Results: The average menarche age of respondent appeared as (15.64±1.92) years old, with prematurity number as 1 421, accounting for 4.6% of the total numbers. Regarding the postponing of dates of birth, the age of menarche in women showed an advancing tendency. Among all the adult women under study, 803 developed near-term obesity, with the prevalence as 2.6%, while the number of long-term obesity was 3 738, accounting for 12.1%. Refining factors of age, lifestyle, menopausal status, hypertension and diabetes showed that the menarche age was related to the risks of both short-term and long-term obesity in women and the ORs (95%CI) were 2.45 (1.74-3.45) and 1.99 (1.69-2.34), respectively. There was no multiplicative interaction shown between the menarche age and menopausal status on long-term obesity (P=0.324). Conclusion: Premature menarche appeared a risk factor for near-term/long-term obesity in adult females.
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Adolescent , Adult , Female , Humans , Age Factors , China/epidemiology , Diabetes Mellitus/epidemiology , Menarche , Obesity/epidemiology , Risk FactorsABSTRACT
Objective To study the relationship between the age of menarche and the nearterm/long-term obesity in adult women.Methods We analyzed the baseline data of 30 895 women with complete data on menarche and body measurement that was from the China Kadoorie Biobank (CKB) study from 2004 to 2008.The age of menarche was divided into three groups:≤12,13-16 and ≥ 17 years old.Prematurity was set at age ≤ 12 years.Multivariate logistic regression was used to analyze the effects of menarche age on the near/long-term obesity in female adults.Results The average menarche age of respondent appeared as (15.64 ± 1.92) years old,with prematurity number as 1 421,accounting for 4.6％ of the total numbers.Regarding the postponing of dates of birth,the age of menarche in women showed an advancing tendency.Among all the adult women under study,803 developed near-term obesity,with the prevalence as 2.6％,while the number of long-term obesity was 3 738,accounting for 12.1％.Refining factors of age,lifestyle,menopausal status,hypertension and diabetes showed that the menarche age was related to the risks of both short-term and long-term obesity in women and the ORs (95％CI) were 2.45 (1.74-3.45) and 1.99 (1.69-2.34),respectively.There was no multiplicative interaction shown between the menarche age and menopausal status on long-term obesity (P=0.324).Conclusion Premature menarche appeared a risk factor for near-term/long-term obesity in adult females.
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Objective To recognize the possibility of Y fragment deletion of Amelogenin gene intuitively and simply according to the genotyping graphs.Methods By calculating the ratio of total peak height of genotyping graphs, the statistics of equilibrium distribution between Amelogenin and D3S1358loci,Amelo-genin X-gene and Amelogenin Y-gene, and different alleles of D3S1358loci from 1968 individuals was analyzed after amplified by PowerPlex? 21 detection kit.Results Sum of peak height of Amelogenin X allele was not less than 60% that of D3S1358loci alleles in 90.8% female samples, and sum of peak height of Amelogenin X allele was not higher than 70% that of D3S1358loci alleles in 94.9% male samples.Conclusion The result of genotyping after amplified by PowerPlex? 21 detection kit shows that the possibility of Y fragment deletion should be considered when only Amelogenin X-gene of Amelo-geninis detected and the peak height of AmelogeninX-gene is not higher than 70% of the total peak height of D3S1358loci.
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OBJECTIVE@#To investigate the relative factors of pharyngo cutaneou fistulas after larynx cancer and lower pharynx cancer surgery.@*METHOD@#The clinical datas of 87 larynx cancer patients and lower pharynx cancer patients admitted were retrospectively analyzed. According to the type of postoperative complications all cases could be divided into pharyngo cutaneou fistulas group and no pharyngo cutaneou fistulas group. Thirty-eight kinds of factors,including age, clinical stage, plasma electrolytes level and type of procedure are in the multivariate analysis, and the variability indicators are in binary-regression analysis.@*RESULT@#Eleven patients had pharyngo cutaneou fistulas (12.64%). Univariate analysis indicated that BMI, pre-operative serum potassium, operation time, cervical lymph dissection, post-operative prealbumin, post-operative hemoglobin, infection and delayed union of incision were the risk factors of pharyngo cutaneou fistulas (P < 0.05). Logistic stepwise regression analysis indicated that post-operative prealbumin and operation time were the independent risk factors.@*CONCLUSION@#To avoid pharyngo cutaneou fistulam, it is very necessary to correct electrolyte disorder and negative nitrogen balance. To shorten the operation time, to avoid incision infection and delayed union were helpfulness, too.