ABSTRACT
Objective To analyze the clinical features of invasive Klebsiella pneumoniae liver abscess syndrome (IKLAS). Methods The clinical data of IKLAS patients diagnosed in China-Japan Friendship hospital from January 2010 to October 2017 was analyzed retrospectively. Results There were 9 patients with IKLAS including 6 males and 3 females aged (56. 77 ± 10. 28)years old. Four cases with diabetes mellitus,one case with impaired glucose tolerance,and two cases with cholelithiasis history. Single abscess (7 / 9),multiple abscess(2 / 9). Involved organs:lung(7 / 9),eyes(3 / 9),soft tissue (1 / 9),joint(1 / 9)and nerve system(1 / 9). Laboratory test showed an elevation of the white blood cell count (8 / 9),the al-anine aminotransferase (9 / 9)and the PCT (7 / 9 ),and only one ESBL positive Klebsiella pneumonia. Three cases with en-dophthalmitis lost their sight,and one with meningitis died. Conclusion IKLAS is common in people with diabetes,and it may be associated with multiple sites of metastasis of the body and lungs are the most involved organ.