Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add filters








Language
Year range
1.
China Pharmacy ; (12): 860-865, 2024.
Article in Chinese | WPRIM | ID: wpr-1013550

ABSTRACT

OBJECTIVE To develop a standard of hierarchical management for patients with chronic obstructive pulmonary disease (COPD) from the perspective of pharmacists. METHODS The triangle hierarchical management model was used as the framework. Through literature research, the indicators of the hierarchical management standard for COPD patients were preliminarily compiled. A questionnaire was designed and administered to 18 experts, and Delphi method was conducted in two rounds to determine the contents of the standard. RESULTS The response rates for both rounds of expert consultation were 100%, with both authority coefficients of experts of 0.903 and Kendall coordination coefficiens of 0.279 and 0.189 for each indicator. The final established standard of hierarchical management for COPD patients included 25 stratified indicators and 17 pharmaceutical hierarchical management indicators. There were 9, 8 and 8 indicators in the high-risk, medium-risk, and stable layers, respectively, considering three aspects: disease, medication, and self-management level. The corresponding first-level, second- level, and third-level pharmaceutical management included 6, 6 and 5 indicators, respectively, including inhalation technical guidance, medication adherence guidance, treatment monitoring, and follow-up, etc. CONCLUSIONS The standard of hierarchical management for COPD patients established by Delphi method is scientific and reliable, which can provide a reference for pharmacists to carry out hierarchical management of COPD patients in China.

2.
China Pharmacy ; (12): 1989-1994, 2023.
Article in Chinese | WPRIM | ID: wpr-980593

ABSTRACT

OBJECTIVE To analyze the research status and development trends of the use of sacubitril/valsartan. METHODS Related literature about the use of sacubitril/valsartan were retrieved from CNKI and the core database of Web of Science. CiteSpace 5.8.R3 software was used to analyze authors, countries/areas, institutions and keywords. RESULTS & CONCLUSIONS Totally 1 193 Chinese literature and 1 060 English literature were included. The number of literature increased, with numerous literature covering the United States (429), the United Kingdom (185) and China (184). ZHANG Jing (5) and Solomon S D (118) published the highest number of Chinese and English articles. The authors of Chinese literature had less cooperation while the authors of English literature were in close contact. Dept. of Cardiology in the First Affiliated Hospital of Zhengzhou University (9), Dept. of Cardiology in the Affiliated Hospital of Xuzhou Medical University (9) and Novartis AG (134) had the highest quantity of publications of Chinese and English literature. The institutions of Chinese literature had a small number of overall publications and less cooperation while the institutions of English literature were closely connected. The clinical efficacy of sacubitril/valsartan for heart failure, hypertension and their complications were research hotspots in Chinese and English literature. Chinese scholars and research teams need to strengthen cooperation and communication in the future, as well as conduct research from the perspectives of sacubitril/valsartan in the treatment of heart failure, hypertension and related complication, the improvement of oxidative stress, and the evaluation of the efficacy of combination therapy with dapagliflozin.

3.
Chinese Journal of Cellular and Molecular Immunology ; (12): 824-827, 2023.
Article in Chinese | WPRIM | ID: wpr-1009436

ABSTRACT

Objective To investigate the effect of blood group serology and polymerase chain reaction with sequence-specific primers (PCR-SSP) on identification and genotyping of ambiguous ABO blood group. Methods Eighty suspicious ABO blood group samples were identified by serology and polymerase chain reaction with sequence-specific primers (PCR-SSP). The final blood group type and the strategy of the transfusion of each case were determined according to the results of serology and PCR-SSP. Results 40 cases were confirmed to be subtypes, and the remaining 40 cases were normal types with weakened antigens or missing antibodies due to other reasons. The results of molecular genetic blood group typing based on PCR-SSP were 41 cases of subtypes (There were 3 discrepancies between two methods: one was Ael identified by serological methods, while its gene type was O2O2; one was common type O, while its gene type was BO1; one was type A, while its gene type was AB.) and 39 cases of normal ones. Conclusion Genotyping technology combined with serological typing has an important significance in identification of ABO blood groups.


Subject(s)
ABO Blood-Group System/genetics , Genotype , Polymerase Chain Reaction , Antibodies , DNA Primers
SELECTION OF CITATIONS
SEARCH DETAIL