ABSTRACT
Purpose To evaluate the diagnostic accuracy of abdominal plain scan and contrast-enhanced multi-slice CT after orally diluted iodide in time segment(Post-ODI ANCCE-MSCT)for gastrointestinal fistula(GIF)secondary to acute pancreatitis(AP).Materials and Methods A total of 108 patients with late AP in the prospective and continuously collected database of Hunan Provincial People's Hospital from January 2017 to December 2022 were retrospectively extracted.Their demographic information and clinical features were recorded and GIF were screened by Post-ODI ANCCE-MSCT.The comprehensive clinical diagnosis results within 5 days thereafter were used as reference standards.The sensitivity,specificity,positive predictive value,negative predictive value and accuracy of Post-ODI ANCCE-MSCT for diagnosing GIF secondary to AP were calculated using a four-cell table,and the consistency of the two methods was evaluated by Kappa test and McNemar's test.Results Sensitivity was 91.5%(95%CI 78.7%-97.2%),specificity was 98.4%(95%CI 90.0%-99.9%),positive predictive value was 97.7%(95%CI 86.5%-99.9%),negative predictive value was 93.8%(95%CI 84.0%-98.0%),and the accuracy was 95.4%(95%CI 91.4%-99.3%),respectively.The Kappa value was 0.905,and P value was 0.375 via McNemar's test.Conclusion Post-ODI ANCCE-MSCT can diagnose GIF secondary to AP in a simple,non-invasive,rapid and accurate way,and provide earlier,more accurate and reliable image basis for clinical diagnosis and treatment.
ABSTRACT
Objective To understand the freshmen’s status of hepatitis B virus infection,immunological effect after vaccina-tion against hepatitis B from a university in Ankang city,to provide a scientific basis for university’s prevention from hepati-tis B.Methods Analyzed the results of five markers of hepatitis B virus infection and alanine aminotransferase (ALT)of 25 895 freshmen in a college in Ankang for resent 12 years,and observed the HBsAb serocoversion in serum 1 year after vacci-nation against hepatitis B and after strengthened immunity.Results The HBeAg positive rate of the freshmen was 4.07%, among which the male was 5.58% (281/5 035),and the female was 3.14% (258/8 214).The difference had significance of statistic (P<0.05).The college students’HBeAg positive rate from rural area and from urban area were 4.77% and 2.93%respectively,the difference had significance of statistic (P<0.05).There was no significant statistic difference in immune effect of hepatitis B vaccine for different sex (χ2=5.80,P<0.05).Their HBsAb positive rate was 95.15% after injected with 10μg hepatitis B and 5μg hepatitis B vaccine,which had significance of statistic (P<0.05).Conclusion The hepatitis B virus infection rate and the hepatitis B protective antibody of the college freshmen in Ankang district was lower than that of the whole country and had a decreased tendency.It showed the male’s infection rate of hepatitis B virus was higher than the female,the rural was higher than the urban,and the immune effect of hepatitis B vaccine proved to be good.It should be-strengthened immunity for non-responders to ensure the immune effect if necessary.