ABSTRACT
OBJECTIVE: Self-esteem and self-consciousness are important determinants of behaviors. This study aimed to explore the relationship between self-esteem and self-consciousness in adolescents using the eye-tracking measurement. METHODS: Fifty-five adolescents with high self-esteem and 58 adolescents with low self-esteem participated in self-consciousness-related eye-tracking experiments of selecting happy, disgusted, and angry facial emotions while recognizing one's own usual expressions and the others' usual expressions toward oneself. RESULTS: When recognizing one's own, adolescents with high self-esteem showed significantly more selection counts and longer fixation time for ‘happy’ than adolescents with low self-esteem. When recognizing the others', adolescents with low self-esteem showed significantly more selection counts and longer fixation time for ‘disgusted’ and ‘angry’ than adolescents with high self-esteem. CONCLUSION: These suggest higher self-esteem is connected to more positive identification of one's usual expressions and others' usual expressions toward oneself. There is a close relationship among low self-esteem, suppressing positive emotions, decreased psychological adjustment, and increased negative emotions.
Subject(s)
Adolescent , Humans , Emotional AdjustmentABSTRACT
OBJECTIVES: Magical ideation refers to belief in forms of causation that by conventional standards are invalid, and is considered to be one of prodromal psychotic symptoms in schizophrenia. This study aimed to investigate the relationship between magical ideation and eye gaze pattern in patients with schizophrenia. METHODS: Eye gaze data were recorded in 23 patients with schizophrenia and 23 healthy controls while performing the reality evaluation task, in which participants should judge the realness of real or unreal pictures. RESULTS: Compared to healthy controls, patients with schizophrenia showed decreased fixation, saccade and area of interest (AOI) fixation counts, and reduced scanpath length. Magical Ideation Scale score in patients with schizophrenia showed negative correlation with the scanpath length in the real condition and the AOI fixation count in the unreal condition. CONCLUSION: These findings suggest that patients with schizophrenia show restricted visual scanning during reality evaluation, and their restricted visual scanning may play an important role in the magical ideation.
Subject(s)
Humans , Magic , Saccades , SchizophreniaABSTRACT
OBJECTIVES: Decision-making in patients with schizophrenia has been known to be inefficient in both cognitive and affective aspects. The purpose of this study was to investigate the influence of anhedonia and self-esteem on the decision-making process in schizophrenia. METHODS: Twenty patients with schizophrenia and 21 healthy controls performed the ‘apparel purchase decision-making task’, during which they were asked to respond to the preference, fitness, and price suitability, before making the final purchase decision. Generalized estimating equation and correlation analysis were conducted to explore for the difference of decision making patterns and influential factors between the two groups. RESULTS: The patients showed lower odds ratio (OR) of the fitness on the apparel purchase decision than the controls [OR 0.190 ; 95% confidence interval (CI) 0.047–0.762, p = 0.019). In the patient group, there was no correlation between the number of purchased trials and the severity of anhedonia, but the number of purchased trials was negatively correlated with the Rosenberg Self-Esteem Scale score at a trend level (R = -0.436, p = 0.055). CONCLUSIONS: Patients with schizophrenia considered the fitness of clothes less than healthy controls on apparel purchasing decisions. Schizophrenia patients with lower self-esteem were intended to buy more clothes.
Subject(s)
Humans , Anhedonia , Clothing , Decision Making , Odds Ratio , SchizophreniaABSTRACT
OBJECTIVES: Disturbance in self-experience has been considered to be a core feature of schizophrenia. Evidence from mirror face-recognition tasks supports the connection between self-face recognition and self-awareness which is a part of self-experience. The aim of this study was to investigate the self-other boundary recognition using morphed face pictures in patients with schizophrenia. METHODS: Twenty-one patients with schizophrenia and twenty-three healthy controls completed the self-face recognition task that consisted of various morphed pictures. Participant's own picture was morphed with each of three different, unknown, gender-matched facial identities in steps of 10% ; each pair producing 11 images with graded blending of facial features. Thirty-three images in total were randomly presented as stimuli in a run, which was repeated three times. Participants were instructed to choose whether the stimulus was self-face or not. RESULTS: Self-face proportion was significantly lower in the schizophrenia group at both recognition start point I and II (33.33% vs. 53.04%, p<0.001 ; 61.43% vs. 70.87%, p=0.01, respectively). Using the mean value of each recognition start point in the control group, we calculated the difference in self-face proportion for each individual with schizophrenia. There was a significant correlation between the degree of this difference and total Scale for the Assessment of Negative Symptoms (SANS) score at recognition start point I (r=0.507, p=0.019). CONCLUSION: The difference in self-other boundary recognition in this study may account for self-disturbance of schizophrenia. Its correlation with SANS total score may reflect the shared nature of persistent disturbance between the disturbance in self-experience and the negative symptom.
Subject(s)
Humans , SchizophreniaABSTRACT
Dermatofibrosarcoma protuberans (DFSP) is a slowly growing dermal spindle cell tumor and its myxoid variant, a rare type of DFSP, is characterized by extensive myxoid degeneration. We present the case of a 69-year-old woman with a multinodular reddish plaque on her trunk. Histopathologically, the tumor was located in the dermis and consisted of uniform spindle-shaped cells, showing strongly positive reaction for CD34, and negative for both S-100 and desmin. In addition to the typical storiform pattern, prominent myxoid stromal changes were demonstrated. Herein, we report an interesting case of myxoid DFSP, rarely reported in the dermatology literature.
Subject(s)
Aged , Female , Humans , Dermatofibrosarcoma , Dermatology , Dermis , DesminABSTRACT
BACKGROUND: The scales of bony fish represent a significant reservoir of calcium and calcification of the elasmoid scale is known to be associated with deposition of mineral crystals from the epidermis to dermis. However, little is known about the exact mechanisms of calcium deposition, mobilization and regeneration occurring in the zebrafish skin. OBJECTIVE: The purpose of this study was to investigate the expression of calcification-related molecular mediators in both the epidermis and dermis of the zebrafish (Danio rerio), using immunohistochemical study. METHODS: We examined the skin of zebrafish in four populations of different ages (i.e. 20 days post-fertilization (dpf), 35 dpf, 50 dpf, and the adult zebrafish), using several immunohistochemical markers, including bone morphogenetic protein 4 (BMP-4), beta-catenin, osteocalcin, osteopontin and osteonectin. RESULTS: BMP-4, osteopontin and osteonectin were moderately expressed in the epidermis of zebrafish after 35 dpf. Also, some of the cells in the upper dermis showed strong positivity for BMP-4, osteocalcin, osteopontin and osteonetin. CONCLUSION: Our results suggest that BMP-4, osteocalcin, osteopontin and osteonectin may play a role in the process of calcification of the elasmoid scale.
Subject(s)
Adult , Humans , beta Catenin , Bone Morphogenetic Protein 4 , Calcium , Dermis , Epidermis , Osteocalcin , Osteonectin , Osteopontin , Regeneration , Skin , Weights and Measures , ZebrafishABSTRACT
BACKGROUND: The TRUE test is a commercially available ready-to-apply patch test widely used in many countries, but no large-scale study is available on the TRUE test in Korea. OBJECTIVE: The purpose of this study was to analyze the type, frequency, and changes in the common contact allergens in Korea using the TRUE test. METHODS: From January 2009 to March 2010, TRUE tests were performed on patients with contact dermatitis at the Departments of Dermatology of 15 hospitals. The epidemiological findings of patients, and the results of the patch tests were analyzed. RESULTS: In total, 795 patch tested cases (246 males, 549 females) were compiled and analyzed. The oldest age distribution was the third decade in both males and females, and housewives and office-workers were the most common jobs, comprising 29.7% and 19.8% of the occupations, respectively. Overall, 65.1% of patients had at least one positive reaction, and the most common allergens were nickel sulfate (34.1%), thimerosal (12.6%), cobalt chloride (11.1%), and p-phenylenediamine (8.4%), in order of frequency. A univariate analysis of multiple variables including age, gender, occupation, and affected sites was conducted and a comparison with a previous multicenter study was also analyzed. CONCLUSION: These results provide the basis for use of the TRUE test in patients with contact dermatitis in Korea.
Subject(s)
Female , Humans , Male , Age Distribution , Allergens , Cobalt , Dermatitis, Contact , Dermatology , Korea , Nickel , Occupations , Patch Tests , Phenylenediamines , ThimerosalABSTRACT
PURPOSE: Childhood headache is different from adulthood headache and according to their age in clinical aspects. This study investigated the clinical differences of primary headache according to ages of children and adolescents. METHODS: A 300 children who did not show abnormalities on neurologic examination or brain CT or MRI were classified into two groups according to their ages. RESULTS: The percentage of those in the migraine group (24.2% vs. 35.9% in Groups 1 and 2 respectively) was higher in Group 2, but it was not statistically significant. In relation to the duration of headache, pain lasting for less than one hour accounted for 59.8% and 40% in Groups 1 and 2, respectively (P=0.001). In relation to the location headaches developed, the frontal region (40.2%) and temporal region (48.1%) were the most common in Groups 1 and 2, respectively (P<0.001). In relation to the nature of the headaches, tightening sensation accounted for the highest percentage in both groups; however, pulsating sensation were more common in Group 2 than in Group 1 (16.2% vs. 8.3%, P=0.038). In relation to the severity of headaches, severe to profound headaches accounted for 35.5% and 61.1% in Groups 1 and 2, respectively (P<0.001). In relation to laterality, unilateral headaches accounted for 12.4% and 26.7% in Groups 1 and 2, respectively (P=0.002). In relation to accompanying symptoms, the incidence of photophobia was higher in Group 2 than in Group 1 (P=0.047). CONCLUSION: Age factors should be considered in the diagnosis of childhood headaches. Also, we consider that there may be a need to establish diagnostic criteria specifically for childhood headaches separately from those for adulthood headaches.
Subject(s)
Adolescent , Child , Humans , Age Factors , Brain , Headache , Headache Disorders, Primary , Hydroxamic Acids , Incidence , Migraine Disorders , Neurologic Examination , Photophobia , SensationABSTRACT
Eccrine porocarcinoma (EP) is a rare malignant tumor arising from the intraepidermal eccrine duct. The tumor cells frequently contain glycogen, but prominent clear cell changes in EP are rarely reported. A 78-year-old woman presented with a slightly pruritic, erythematous, verrucous plaque on her left thigh. Histopathological examination revealed intraepidermal tumor cell nests composed of small basaloid cells and duct-like structures lined by periodic acid-Schiff (PAS)-positive cuticles. Besides the typical findings of EP, clear cell changes were predominantly observed in the tumor cell aggregations. Herein we report a case of the clear cell variant of EP rarely reported in previous literature.
Subject(s)
Aged , Female , Humans , Cell Aggregation , Eccrine Porocarcinoma , Glycogen , ThighABSTRACT
Dermatofibroma is a common benign dermal tumor characterized by a proliferation of fibroblast-like spindle cells. Over the years, more than 25 clinicopathologic variants of dermatofibroma have been recognized and recently additional erosive and ulcerated variants have also been reported. A 32-year-old woman presented with an ulcerative nodule on the scalp. This skin lesion first appeared about 2 months ago and histopathologic examination revealed proliferation of factor XIIIa-positive spindle cells with central necrosis. In this review, we report a rare case of ulcerated dermatofibroma and review the relevant literature.