Sesquiterpenoids from the leaves of Sarcandra glabra / 中国天然药物

Sarglanoids A-F, six new sesquiterpenoids belonging to eudesmane (1-5) and eremophilane (6) types, were isolated from the leaves of Sarcandra glabra, a famous traditional Chinese medicine (TCM). Their structures including absolute configurations were elucidated through extensive spectroscopic analysis and electronic circular dichroism (ECD) calculations. Compounds 1-2 were rare N-containing eudesmane-type sesquiterpenoids. Compound 3 exhibited inhibitory activity against nitric oxide (NO) production in lipopolysaccharides (LPS)-induced RAW 264.7 cells with IC50 values at 20.00 ± 1.30 μmol·L-1. These findings provide scientific evidence for sesquiterpenoids as the material foundation of S. glabra.

Bone histomorphometry study in agglutination of femoral condyle of dog after being compressed / 华西口腔医学杂志

<p><b>OBJECTIVE</b>This study simulated clinical implant surgery using squeeze technique by establishing a rational animal model. To measure the morphologic parameters in order to observe the agglutination of the cancellous bone after being compressed. The study wanted to get some favourable support of implant squeeze technique in bone healing and obtaining primary stabilities of implants, so as to provide some reasonable and valid guidance in the application and improvement of implant squeeze technique.</p><p><b>METHODS</b>The cancellous bone in condyles of femur of dog had been chosen as the experimental position, prepared the implant holes using squeeze technique according to different compressing extent (0, 0.6, 1.2, 2.0 mm), and then inserted the corresponding implants into them. After different healing periods (1, 2, 4, 12 weeks), the mongrel dogs were sacrificed and the hard tissue slices were made and then the morphologic parameters were measured.</p><p><b>RESULTS</b>The morphologic parameter of the bone tissue shows that after being compressed, the trabecular bone thickness was almost constant, while the trabecular bone number increased, and the trabecular bone spacing decreased, obviously in the 1-week and 2-week groups. The differences went down gradually along with the extend of healing time.</p><p><b>CONCLUSION</b>The clinical implant surgery using squeeze technique can improve peri-implant bone density so it is good for obtaining primary stabilities of implants.</p>

A clinical study of immediate dental implant and immediate restoration / 中华口腔医学杂志

<p><b>OBJECTIVE</b>To evaluate the clinical results of immediate implant and immediate restoration and to discuss the applying principles of these techniques.</p><p><b>METHODS</b>Fourteen cases underwent immediate implant surgery for 37 dental implants immediately after the teeth or roots were extracted. Among them, 6 cases (14 implants) received immediate restoration after implant placement. The second stage operation and final restoration were performed 4 months on average postoperatively, and the mean follow-up time was 22 months.</p><p><b>RESULTS</b>Two implants from 1 case were lost at 3 weeks after immediate implant and immediate restoration. The rest cases achieved good clinical results. Accumulative 4-year survival rate was 94.6%.</p><p><b>CONCLUSIONS</b>The result of immediate implant and immediate restoration is predictable if the cases are properly selected.</p>