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【Objective】 To evaluate the therapeutic value of radiotherapy for ovarian metastasis from small cell lung cancer. 【Methods】 Two patients with ovarian metastasis from small cell lung cancer were recruited, and the value of radiotherapy in the system treatment strategies was analyzed combined with literature reports. 【Results】 The two patients both benefited from local radiotherapy plus system treatment. One was still in complete remission, and compared to that reported in the literature, the local PFS improved to 21 months. 【Conclusion】 Although the prognosis of small cell lung cancer with ovarian metastasis is still poor, radiotherapy might be one of the systematic treatment strategies for improving the survival time of these patients.
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【Objective】 To analyze the clinical and pathological characteristics of mucinous tubular and spindle cell carcinoma （MTSCC） in the kidney so as to evaluate the value of radiotherapy in local treatment of refractory MTSCC. 【Methods】 A case of MTSCC with recurrent recurrence and metastasis was reported， and the existing literature on MTSCC was reviewed and analyzed to explore the value of radiotherapy in the treatment of MTSCC. 【Results】 After three operations， postoperative pathology of the patient showed mucinous tubular and spindle cell carcinoma of the kidney. Radiotherapy was performed in the first recurrence area， and long-term follow-up in the tumor bed area showed no recurrence. 【Conclusion】 MTSCC， a rare renal epithelial tumor， has the low-grade malignance in most cases， and rarely recurs and has metastasis. This patient had repeated recurrence and metastasis before surgery， but after tumor bed radiotherapy after the first recurrence no lesion was found， suggesting that radiotherapy plays a certain role in preventing local recurrence. It is necessary to further explore the value of radiotherapy in the treatment of MTSCC.
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly infectious and causes severe harm to human health. Almost everyone is susceptible to coronavirus disease 2019 (COVID-19). It is thought that COVID-19 is transmitted via droplets and close contact without protection. Aerosol propagation is possible in confined space. Preclinical patients and recessive infected people have certain infectivity, which increases the difficulty of prevention and control. Treatment for cancer patients needs to be continuous. Cancer patients on radiotherapy once a day need continuous treatment. Since a large number of patients come to the hospital for radiotherapy, medical staff need to contact them frequently. It is particularly important to absolutely avoid cross infection between tumor patients and medical staff. To this end, we have developed detailed management strategies, including establishing a core group, standardizing inpatient diagnosis and treatment processes, standardizing outpatient radiotherapy patient process, strengthening the ward and room disinfection, strengthening personnel management and other measures. We hope this paper provides reference for the department of tumor radiotherapy.
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Objective: To analyze the clinical features and treatment of tracheal adenoid cystic carcinoma (TACC) so as to explore the therapeutic value of intensity-modulated radiotherapy in treating locally advanced inoperable tracheal bronchial adenoid cystic carcinoma. Methods: A patient with locally inoperable TACC was retrospectively reported with intensity-modulated radiotherapy, and the efficacy of interventional radiotherapy for locally inoperable TACC was analyzed. Results: After multi-course chemotherapy and radical radiotherapy, the patient was given intensity-modulated radiotherapy of DT46 GY/23F in the trachea and the bronchus and in the drainage area of mediastinal lymph node. Then the tumor area of the constricted trachea and the right main bronchus was given the radiotherapy up to DT60 GY/30F. The symptoms of shortness of breath and cough disappeared, and the tracheal and bronchial lesions were completely relieved. By combining with existing reports, single radiotherapy in locally advanced inoperable TACC can achieve survival of over one year and as long as 5 to 10 years in some patients. Results: Intensity-modulated radiotherapy has a positive significance in the treatment of locally advanced inoperable TACC.
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Objective:To investigate the clinical efficacy of postoperative radiotherapy combined with compound matrine injection on the patients with breast cancer.Methods:Eighty-three patients with breast cancer received breast-conserving and sentinel lymph node biopsy before the study who were admitted in our hospital were divided into the control group and observation group.Forty-two patients in control group were treated with postoperative radiotherapy,and forty-one patients in observation group were received postoperative radiotherapy combined with compound matrine injection.The CA125,CA153,CA724,levels of CD3+,CD4+,CD8+,CD4+/CD8+,NK,and adverse reaction in the two groups were detected and compared.Results:After treatment,the CA125,CA153,and CA724 in both groups were obviously decreased (P＜0.05),which were significantly lower in the observation group than those of the control group (P＜0.05).CD3+,CD4+,CD8+,CD4+/CD8+,and NK cell in the observation group showed remarkable improvement (P＜0.05) compared with those before treatment.And CD3+,CD4+,CD4+/CD8+,and NK cell of the observation group were significantly higher than those of the control group,while CD8+ was much lower (P＜0.05).During the treatment period,the incidence of skin reaction over grade Ⅱ,and myelosuppression in observation group were much lower than those of control group (P＜0.05).Conclusion:Postoperative radiotherapy combined with compound matrine injection had good ability in enhancing the cellular immune function and reducing adverse reaction on the patients with breast cancer.
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Objective To investigate the relation of pelvic three-dimensional conformal radiotherapy(3D-CRT) target with rectal dose distribution and irradiation volume in cervical cancer.Methods In 45 patients with cervical cancer(Ⅱa-Ⅲb) treated in our department from September to December 2006,we compared rectal dose distribution in different treatment plans: conventional radiation,4-field box radiation,4-field oblique radiation and 5-field radiation,and studied the relationship between rectal irradiation volume and dose in the target area.Results Compared with that of the other models,the dose distribution of CTV in 3D-CRT was relatively poor although it could satisfy the demand of treatment;dose distribution of D90,D80 and D50 in the radiated rectum differed significantly(P