1.
Journal of Experimental Hematology
;
(6): 115-119, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-278786
ABSTRACT
Stromal cell derived factor (SDF), expressing on bone marrow stromal cells is a CXC-type chemokine, which specifically chemoattracts hematopoietic stem cells (HSCs) expressing CXCR4. SDF plays important roles in homing and mobilizing of HSCs. In this paper the regulatory mechanism of SDF/CXCR4 in the HSC migration process is mainly reviewed.