ABSTRACT
To investigate the biomechanical influences on two different cleft maxillary 3D finite element models pre- and post-alveolar bone graft, we developed a cleft palate bony model from a 17 year cleft palate male CT scan data and built an alveolar bone-grafted cleft maxillary 3D finite element model through gluing the graft model. Apply vector lip force on the anterior face of the models. Study the press (including S3 principal, S1 principal, von Mises and shear) distribution properties and localized area. The results suggested that the press principal spreads along the alveolar ridge and formed several focused areas. After bone grafted, the shear stress tends to be evenly. The grafted alveolar could resist the medially deformation of alveolar crest and the shear stress to the nasal base bony structure. The conclusions from results demonstrated that the deformation of alveolar ridge is possibly due to the lip pressure after the lip repair. The shear stress along the alveolar ridge could cause the severity of the dentition. The grafted bony structure could even the shear stress distribution evenly other than the distribution properties.
Subject(s)
Adolescent , Humans , Male , Alveolar Process , General Surgery , Alveolar Ridge Augmentation , Methods , Biomechanical Phenomena , Bone Transplantation , Cleft Palate , Diagnostic Imaging , General Surgery , Finite Element Analysis , Imaging, Three-Dimensional , Maxilla , Diagnostic Imaging , General Surgery , Models, Biological , Tomography, Spiral ComputedABSTRACT
Objective:To establish a three-dimensional finite element model of maxillary complex with cleft palate.Methods:Spiral CT scanning images of maxilla were obtained from a male patient with cleft palate.The data were used to build up different range finite element model of maxillary structure with cleft palate using ANSYS software.Result:The model of maxillary complex with cleft palate could reflect the maxillary structural properties of the cleft palate.Conclusions:Combined with spiral CT and ANSYS software technique finite element model of cleft palate maxillary complex can be established.
ABSTRACT
According to the characteristic of the practice in the outpatient dentofacial surgery,we analyzed the prominent contradiction in the process.With the progress of the medical service law and the innovation of the medical treatment mode,we must pay more attention to the ethics problems on the medical education.Before practice,we must strengthen the students' training in stimulator,the concept of legal,ethics,communication skill and so on.Teachers and hospitals should take the responsibility.The relevant laws and regulations ought to be modified step by step to ensure the practice.
ABSTRACT
This paper has analysed the particularity of practice and teaching of oral and maxillofacial surgery.Binding with the change of medical pattern in recent years,the change of relation of doctors and patients as well as the present of "the People's Republic of China Practical Doctor Law"and "Rules of Sitling Malpractice",it has discussed that we should simultaneously think highly of raising to practice ability, reinforcing education of medical ethics, emphasizing legal consciousness and deepening ethics idea during practice teaching of oral and maxillofacial surgery,which can ensure well development of interns.
ABSTRACT
This article mainly discusses the psychological characteristics of old patients having tooth pulled out on the view of medical ethics and tries to acquire its corresponding countermeasures.Through strenghtening the ethical education on oral and maxillofacial surgeons and giving right guidance to patients,it's helpful to lighten patients' burden and achieve good relationship and cooperation between doctors and patients to complete treatment successfully.
ABSTRACT
Tissue engineering of oral and maxillofacial surgery is a newly subject and animportant branch of tissue engineering. The study is to evaluate fundamental medical ethics principle in the tissue engineering of oral and maxillofacial surgery on the view medical ethcs. Strengthening the ethical education on oral and maxillofacial surgeon and right education on patients are in favor of development of tissue engineering in the oral and maxillofacial surgery.
ABSTRACT
Overtreatment is not only an economic phenomenon, but also an ethics problem at the same time. It is precisely a medical - social problem. This paper analyzes the reasons of overtreatment in oral disease from the view of medical elthics. Furthermore, it provides the strategy which the doctor, the patient, the medical establishment and the social shoud be adopted on overtreatment in oral disease.
ABSTRACT
As an exposing part of the human body,facial surface is easy to be injured in our daily lives.With the increase of living standards,the patients have an ever more urgent require for aesthetic treatment for the medical and plastic surgical treatment for the exposing parts of body,especially for the facial surface.But we found in the clinical work some aesthetic treatment were not satisfying,and some patients even needed a second restitution.We have analyzed the reasons for this phenomenon and proposed some corresponding solving methods.
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Objective To observe the effects of nerve growth factor (NGF) on growth of human hair follicles in vitro. Methods NGF was added to the model of human hair follicles in vitro. The length and the DNA synthesis rate of human hair follicles in vitro were measured. Results We found both 100 ?g?L -1 NGF and 125 mg?L -1 minoxidil significantly accelerated the growth of human hair follicles in vitro (P
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Objective To study the mechanism of increased sensitivity to cisplatin by nm23-H1.Methods The plasmid,pCMV-BamH1-Neo-nm23-H1,was transfected to cell line Tca8113 by lipofection strategy and was selected by G418 for 5 weeks.The stable products of nm23-H1 gene were identified by Immunohistofluorescence and Western-blotting.Using MTT and flow cytometer,we detected the changes of cell mortality rate,apoptosis and mitochondrial membrane potential.Results We successfully established the cell line of stable overexpression of nm23-H1.In vitro,the cell mortality rate and apoptosis were increased significantly in stable expression cell line of nm23-H1,compared with those in Tca8113 cell line of non-transfection;this effect could be inhibited by oubain which is an inhibitor of Na(+)/K(+)-ATPase.Mitochondrial membrane potential was decreased significantly in stable expression cell line of nm23-H1.Conclusion Nm23-H1 can increase the sensitivity of cisplatin on Tca8113 cell line;The mechanism may be the mitochondrial membrane potential is decreased by nm23-H1 so that intracellular platinum are increased to finally cause the apoptosis and necrosis of cells.