ABSTRACT
@#Objective To investigate the relationship between leukoaraiosis in spontaneous supratentorial intracerebral hemorrhage.Methods Patients with spontaneous supratentorial intracerebral hemorrhage who were admitted to the Department of Neurology,the First Affiliated Hospital of China Medical University from October 2015 to October 2017 were enrolled retrospectively.The patients were required to complete the cranial CT within 12 hours after ICH symptoms onset and the follow-up cranial CT within 48 hours.Hematoma volume and the volume of perihematoma edema were measured with Image J.The Van Swieten scale was used to evaluate the severity of leukoaraiosis.The differences in clinical,imaging and laboratory data such as hematoma location,hematoma shape,and degree of leukoaraiosis between early hematoma expansion group and nonexpantion group were compared to determine whether leukoaraiosis is an independent risk factor for early hematoma expansion.Results 94 cases (33.3%) developed early hematoma expansion.Multivariate logistic regression analysis showed that VSS score (OR=1.358,95%CI 1.139~1.619,P=0.001) and smoking degree (OR=1.286,95%CI 1.029~1.606,P=0.027) are independent risk factors for early hematoma expansion in spontaneous supratentorial intracerebral hemorrhage.Conclusion Leukoaraiosis is closely related to the early expansion of hematoma in spontaneous supratentorial intracerebral hemorrhage,that is,the more serious the degree of leukoarais,the higher the incidence of early hematoma expansion.