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Abstract Objective: Emergence delirium is a common complication in children. Recorded mother's voice, as a non-pharmacological measure, is increasingly used to prevent the emergence of delirium in pediatric patients, but sufficient evidence is still needed to prove its efficacy. Methods: Embase, PubMed, Cochrane Library, Web of Science, CINAHL, and Sinomed databases were searched for randomized controlled trials exploring the efficacy of recorded mother's voice in preventing the emergence of delirium in pediatric patients undergoing general anesthesia. The original data were pooled for the meta-analysis with Review Manager 5.4.1. This study was conducted based on the Cochrane Review Methods. Results: Eight studies with 724 children were included in the analysis. Recorded mother's voice reduced the incidence of emergence delirium when compared with either no voice (RR: 0.45; [95 % CI, 0.34 - 0.61]; p < 0.01; I2 = 7 %) or stranger's voice (RR: 0.51; [95 % CI, 0.28 - 0.91]; p = 0.02; I2 = 38 %) without increasing other untoward reactions. In addition, it shortened the post-anesthesia care unit stay time when compared with no voice (MD = -5.64; [95 % CI, -8.43 to -2.58]; p < 0.01, I2 = 0 %), but not stranger's voice (MD = -1.23; [95 % CI, -3.08 to 0.63]; p = 0.19, I2 = 0 %). It also shortened the extubation time and reduced the incidence of postoperative rescue analgesia. Conclusion: The current analysis indicated that recorded mother's voices could reduce the incidence of emergency delirium, shorten post-anesthesia care unit stay time and extubation time, and decrease the incidence of postoperative rescue analgesia in children.
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Objective To investigate the effect of constant speed pump infusion of esmketamine on emergence agitation(EA)after target-controlled infusion of etomidate.Methods A total of 120 patients scheduled for middle ear tympanoplasty under target-controlled infusion of etomidate,61 males and 59 fe-males,aged 18-64 years,BMI 18-30 kg/m2,ASA physical status Ⅰ or Ⅱ,were randomly divided into two groups:the esmketamine group(group E)and the control group(group C),60 patients in each group.From the beginning of anesthesia induction to 30 minutes before the end of operation,esmketamine 0.2 ml·kg-1·h-1 in group E and saline injection 0.2 ml·kg-1·h-1 in group C were injected,respectively.The operation time,anesthesia time,awakening time,extubation time,and the duration in PACU were re-corded.The incidence of EA,the VAS pain scores when leaving PACU and 1 day after operation,the inci-dence and VAS score of nausea and vomiting 1 day after operation were evaluated.The anxiety and depres-sion scores of the two groups were evaluated before operation,1 day and 2 days after operation.Results The incidence of EA,VAS pain score when leaving PACU and 1 day after operation in group E were signifi-cantly lower than those in group C(P<0.05).There was no significant difference in operation time,anes-thesia time,awakening time,extubation time,the duration in PACU,incidence and VAS score of nausea and vomiting 1 day after operation,and the indexes of anxiety and depression at different time points be-tween the two groups.Conclusion Esmketamine pump infusion combined with etomidate target-controlled infusion can reduce emergence agitation and promote postoperative recovery.
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AIM: To investigate the effect of the timing of satisfactory sedation with preoperative oral midazolam on anesthesia induction and recovery in children undergoing adenotonsillectomy. METHODS: A total of 147 children undergoing elective adenotonsillectomy, with ASA physical status orⅡ, aged 2-7 years were selected from November 2022 to June 2023 in the Second Affiliated Hospital of Wenzhou Medical University. The children were orally administered 0.5 mg/kg midazolam in preoperative waiting area and were divided into 10-20 min (rapid onset, M1 group) and 21-30 min (slow onset, M2 group) based on the satisfactory sedation time, or equal volume of sugar pear drink orally (blank control group, C group). Children in all three groups received a general anesthesia method of propofol+fentanyl combined with sevoflurane induction and sevoflurane maintenance. The primary outcome measures were the induction compliance checklist (ICC) score and the pediatric anesthesia emergence delirium (PAED) score in the post-anesthesia care unit (PACU) to assess the occurrence of emergence agitation (EA), and the secondary outcome measures included the parental separation anxiety scale (PSAS), sedation Ramsay score, surgery duration, recovery time, PACU stay time, discharge time, the incidence of perioperative respiratory adverse events (PRAE) and other adverse events in the ward. RESULTS: 147 children were included in the result analysis, with 49 cases in each group. The proportion of perfect induction (ICC=0) were significantly higher in two M groups than that in group C (95.9% vs. 91.8% vs. 61.2%, P=0.001). The maximum and average PAED score in PACU in group M1 showed a significantly higher (6.4±5.0 vs. 4.4 ± 4.1, P=0.029; 5.2 ± 4.5 vs. 3.4 ± 3.6, P=0.030), and the incidence of EA was significantly higher than those in group C (10.2% vs. 30.6%, P=0.022), and increased compared to the group M2 (OR= 0.581, 95%CI 0.231-1.463, P=0.354). There was no statistically significant difference in the maximum and average PAED scores, incidence of EA between group M2 and group C (P>0.05). The Ramsay score and PSAS score in two M groups were higher, PACU stay time and recovery time was longer than those in group C (P0.05). CONCLUSION: Preoperative oral midazolam can improve the ICC and PSAS scores of children during induction, but it also leads to prolonged recovery time and PACU retention time. The rapid onset of midazolam did not result in better induction and recovery quality, but instead increased the incidence of EA and postoperative pain score.
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Objective:To evaluate the effect of ultrasound-guided adductor canal combined with knee joint posterior capsule space block on the recovery period delirium in elderly patients undergoing total knee arthroplasty (TKA).Methods:A total of 68 elderly patients who underwent unilateral TKA at the Nanjing First Hospital from December 2021 to December 2022 were selected. They were randomly divided into a control group ( n=34) and an observation group ( n=34) using a random number table method. Both groups received general anesthesia, and the observation group received ultrasound-guided myofascial tube combined with knee joint posterior capsule space block before the surgery began. The incidence of delirium within 24 hours after surgery was mainly observed in two groups of patients. The surgical time, recovery time, intraoperative blood loss, infusion volume, total use of propofol and remifentanil were recorded; The resting and motor Visual Analogue Scale (VAS) scores of the patient were recorded at 4, 8, and 24 hours postoperatively. The patient′s serum tumor necrosis factor-α (TNF-α) and melatonin levels were measured on the day before surgery, the evening after surgery, and the first day after surgery. The subjective sleep quality score was recorded on the first day after surgery; The total dosage of sufentanil for patient-controlled intravenous analgesia (PCIA) within 24 hours after surgery, the effective number of compressions (P1) and actual number of compressions (P2) of PCIA, and the number of cases of additional oxycodone analgesia were recorded; The occurrence of respiratory depression, excessive sedation, nausea, and vomiting within 24 hours after surgery was recorded; The occurrence of complications of nerve block in the observation group was recorded. Results:The incidence of delirium during the recovery period in the observation group was lower than that in the control group ( P<0.05). The dosage of propofol and remifentanil in the observation group was lower than that in the control group (all P<0.05), and the awakening time was shorter than that in the control group ( P<0.05). The VAS scores at rest and exercise at 4, 8, and 24 hours after surgery in the observation group were lower than those in the control group (all P<0.05). Compared with the day before surgery, the observation group showed an increase in melatonin levels on the night after surgery ( P<0.05) and an increase in TNF-α levels on the first day after surgery ( P<0.05); The control group had a decrease in melatonin levels on the first day after surgery ( P<0.05), and an increase in TNF-α levels on the night and day after surgery (all P<0.05). The serum melatonin levels in the observation group were higher than those in the control group on the evening and first day after surgery (all P<0.05), and TNF-α levels were lower than those in the control group (all P<0.05). The subjective sleep quality score of the observation group showed that the total dosage of PCIA sufentanil, P1, P2, and the number of cases of additional oxycodone analgesia within 24 hours after surgery were lower than those of the control group (all P<0.05). The incidence of nausea in the control group (13 cases, 38.2%) was higher than that in the observation group (3 cases, 8.8%) ( P<0.05). Conclusions:In elderly patients undergoing unilateral TKA under general anesthesia, preoperative use of ultrasound-guided adductor tube combined with knee joint posterior capsule space block can effectively reduce the occurrence of postoperative delirium.
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Abstract Background: Emergence Delirium (ED) is an essential condition in the immediate postoperative period. Systematic review and meta-analysis of randomized controlled trials have concluded that the effect of ketamine on postoperative delirium remains unclear. The present study sought to evaluate if the intraoperative use of ketamine for postoperative analgesia is associated with postoperative ED in laparoscopic surgeries. Methods: A prospective observational study was performed in the PostAnesthetic Care Unit (PACU) to evaluate patients who had undergone laparoscopic surgery under a rigid intraoperative anesthesia protocol from July 2018 to January 2019. Patients submitted to laparoscopic surgery for cholecystectomy, oophorectomy, or salpingectomy with a score ≥1 on the Richmond Assessment Sedation Scale (RASS) or ≥2 on the Nursing Delirium Screening Scale (Nu-DESC) were considered to have ED. t-test, Chi-Square test or Fisher's exact tests were used for comparison. Results: One hundred and fifteen patients were studied after laparoscopic surgery. Seventeen patients (14.8%) developed ED, and the incidence of ED in patients who received ketamine was not different from that of other patients (18.3% vs. 10.6%, p = 0.262). Patients with ED had more postoperative pain and morphine requirement at the PACU (p = 0.005 and p = 0.025, respectively). Type of surgery (general surgery, OR = 6.4, 95% CI 1.2‒35.2) and postoperative pain (OR = 3.7, 95% CI 1.2‒11.4) were risk factors for ED. Conclusion: In this study, no association was found between ED and intraoperative administration of ketamine in laparoscopic surgeries. Type of surgery and postoperative pain were risk factors for ED.
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Abstract Objective: to detect the incidence of postoperative delirium in critically ill patients admitted to a surgical intensive care unit and to evaluate the predisposing and precipitating factors associated with postoperative delirium in critically ill patients admitted to a surgical intensive care unit. Method: this is a prospective cohort study of 157 critically ill surgical patients. Fisher's exact test and Chi-square test were used for the association between factors and the occurrence of delirium, the Wilcoxon test for numerical variables, and the logistic regression model for the analysis of predisposing and precipitating factors. Results: the incidence of delirium was 28% (n=44). Age was a significant predisposing factor (p=0.001), followed by the length of surgery (p<0.001), blood transfusion (p=0.043), administration of crystalloids (p=0.008), and anti-inflammatory drugs (p=0.037), which were the precipitating factors identified. The best-adjusted models were: age, length of surgery, non-administration of anti-emetics, use of sufentanil, and blood transfusion. Conclusion: delirium is a frequent condition in critically ill adults undergoing surgery and the existence of precipitating and predisposing factors is relevant to the outcome, with the anesthetic-surgical procedure as the catalyst event.
Resumo Objetivo: detectar a incidência de delirium pós-operatório em pacientes críticos internados em uma unidade de terapia intensiva cirúrgica e avaliar os fatores predisponentes e precipitantes associados ao delirium pós-operatório em pacientes críticos internados em uma unidade de terapia intensiva cirúrgica. Método: trata-se de um estudo de coorte prospectivo com 157 pacientes críticos cirúrgicos. Utilizou-se teste Exato de Fisher e qui-quadrado para a associação entre os fatores e ocorrência de delirium, teste de Wilcoxon para as variáveis numéricas e o modelo de Regressão Logística para a análise dos fatores predisponentes e precipitantes. Resultados: a incidência de delirium foi 28% (n=44). O fator idade apresentou-se predisponente significativo (p=0,001), seguido do tempo de cirurgia (p<0,001), a transfusão sanguínea (p=0,043), a administração de cristaloides (p=0,008) e anti-inflamatórios (p=0,037), estes foram os fatores precipitantes identificados. Obteve-se como melhor modelo ajustado: idade, tempo de cirurgia, a não administração de antieméticos, o uso de sufentanil e a transfusão sanguínea. Conclusão: o delirium consiste em acometimento frequente para adultos críticos cirúrgicos e a existência de fatores precipitantes e predisponentes tornam-se relevantes para o desfecho, tendo-se o procedimento anestésico-cirúrgico como evento catalisador.
Resumen Objetivo: detectar la incidencia de delirium postoperatorio en pacientes críticos internados en una unidad de terapia intensiva quirúrgica y evaluar los factores predisponentes y precipitantes asociados al delirium postoperatorio en pacientes críticos internados en una unidad de terapia intensiva quirúrgica. Método: se trata de un estudio de cohorte prospectivo con 157 pacientes críticos quirúrgicos. Se utilizó la prueba exacta de Fisher y chi-cuadrado para la asociación entre los factores y ocurrencia de delirium, prueba de Wilcoxon para las variables numéricas y el modelo de regresión logística para el análisis de los factores predisponentes y precipitantes. Resultados: la incidencia de delirium fue 28% (n=44). El factor edad se presentó como predisponente significativo (p=0,001), seguido del tiempo de cirugía (p<0,001), la transfusión sanguínea (p=0,043), la administración de cristaloides (p=0,008) y antiinflamatorios (p=0,037), estos fueron los factores precipitantes identificados. Se obtuvo como mejor modelo ajustado: edad, tiempo de cirugía, la no administración de antieméticos, el uso de sufentanilo y la transfusión sanguínea. Conclusión: el delirium es un acometimiento frecuente para adultos críticos quirúrgicos y la existencia de factores precipitantes y predisponentes se vuelven relevantes para el desenlace, teniendo el procedimiento anestésico-quirúrgico como evento catalizador.
Subject(s)
Humans , Critical Care , Measures of Association, Exposure, Risk or Outcome , Neuroscience Nursing , Emergence DeliriumABSTRACT
At the wetland farm of S.V. Agricultural College, Acharya N.G. Ranga Agricultural University, Tirupati, Andhra Pradesh, India, a field experiment was carried out during the (rainy season) kharif 2020 to evaluating weed management strategies and the differential effects of herbicides on weed dynamics and crop performance of foxtail millet [Setaria italica (L.) Beauv] grown under the irrigated conditions of Rayalaseema. The current study has shown that the application of pre-emergence pretilachlor 500 g ha-1 with intercultivation at 20 DAS was followed by hand weeding twice at 20 and 40 DAS and it led to the highest weed control efficiency, including foxtail millet's nutrient uptake, and the lowest weed density and dry weight. In unweeded check, a heavy weed infestation reduced the amount of nitrogen, phosphorus, and potassium absorbed by crop by 45.67, 18.03, and 35 kg ha-1, respectively. Crop growth parameters, straw and grain production was increased by hand weeding twice, however the benefit-cost ratio lagged behind the most effective weed management strategy, which is applying pre-emergence of pretilachlor 500 g ha-1with intercultivation at 20 DAS. The present experiment indicated that wherever the labour availability for hand weeding is abundant and cheaper, one can go for hand weeding or opt for the said herbicide recommendation taking into the economical considerations.
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Rice (Oryza sativa L.) is a major source of food for more than half of the world population especially in South and Southeast Asia and Latin America. A field experiment was conducted at Krishi Vigyan Kendra, Yamunanagar district, Haryana during Kharif season of 2022 to study the effect of pre and post-emergence herbicides combinations herbicides in direct-seeded rice under irrigated condition. The experiment was laid out in a Randomized block design with three replications. The weed management treatments were T1: Pendimethalin + pyrazosulfuron T2:Pendimethalin + pyroxasulfone, T3:Pretilachlor + pyrazosulfuron, T4: Fenoxaprop-p-ethyl with safener + ethoxysulfuron,T5: Cyhalofop-butyl + penoxsulam and metsulfuron-methyl + chlorimuron-ethyl, T6.:Triafamone + ethoxysulfuron, T7: Pendimethalin + pyrazosulfuron fb bispyribac-sodium, T8: Pendimethalin + pyroxasulfone fb bispyribac-sodium, T9:Pretilachlor + pyrazosulfuron fb bispyribac-sodium, T10:Pendimethalin fb fenoxaprop-p-ethyl + ethoxysulfuron T11: Weed free, T12:Weedy check. Among herbicides, application T10 (pendimethalin fb fenoxaprop-p-ethyl + ethoxysulfuron) and T5 (cyhalofop-butyl+ penoxsulam and metsulfuron methyl + chlorimuron ethy (pre-mix) was superior over other treatment. Application of pendimethalin fenoxaprop-p-ethyl + ethoxysulfuron reduced 58.89% grassy weed and 50 % BLWs compared to weedy check plot at 60 DAS. Assessment at 60 DAS and at harvest showed that bispyribac-sodium was effective in controlling E. colona and E. crus-galli. However, bispyribac-sodium did not control D. aegyptium and L. chinensis. Fenoxaprop significantly reduced the densities of Dactyloctenium aegyptium, L. chinensis, and Digitaria sanguinalis. Fenoxaprop tank-mix with ethoxysulfuron appeared to be synergistic for the control of E. crusgalli and E. colona, and Cyperus sp. as this tank mixture. Integration of pendimethalin fb fenoxaprop-p-ethyl+ ethoxysulfuron provided control of all type of weeds with highest grain yield (6.1 t ha-1) among different treatments which was statistically at par with weed free (6.3 t ha-1). In economics points of views, the highest B-C ratio (3.03) was obtained in cyhalofop-butyl + penoxsulam + metsulfuron methyl + chlorimuron ethy followed by pendimethalin fb fenoxaprop-p-ethyl + ethoxysulfuron (2.98).
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Wheat (Triticum aestivum) is second most important staple crop in India after rice. Weeds have emerged as the major biotic stress in wheat. Post-emergence herbicidal combinations are used widely to control the complex weed flora in wheat crops. A field experiment was carried out to study the “Effects of herbicides and nano urea mixture on weeds, yield attributes and yield of wheat (Triticum aestivum)”. The experiment was performed in randomized blocked design with three replications and fourteen treatments in Rabi season 2022-23 at Agronomy Research Farm, CCS Haryana Agricultural University, Hisar. Significantly minimum weed count (1.52 m-2) and dry weight (1.49 g m-2) and maximum weed control efficiency (88.6%) of Phalaris minor and broadleaved weeds (87%) was recorded with application of clodinafop + metribuzin 60 + 210 g ha-1 with nano urea 3 ml L-1 followed by clodinafop + metribuzin 60 + 210 g ha-1 at 90 DAS. In case of yield attributes i.e. number of effective tillers per meter row length (92.5), spike length (11.4 cm), number of grains spike-1 (55.9) and 1000-grain weight (43.8) were higher with application of clodinafop + metribuzin 60 + 210 g ha-1 with nano urea 3 ml L-1 followed by clodinafop + metribuzin 60 + 210 g ha-1. Grain yield (5876 kg ha-1) and B:C (1.94) was recorded higher with application of clodinafop + metribuzin 60 + 210 g ha-1 with nano urea 3 ml L-1 followed by clodinafop + metribuzin 60 + 210 g ha-1 which was significantly higher than weedy check but at par with the weed free treatment.
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The present investigation entitled “Effect of weed management practices on growth, yield and quality of okra Abelmoschus esculentus (L.) Moench)” was conducted at Vegetable Research Farm, Chandra Shekhar Azad University of Agriculture and Technology, Kanpur during kharif season 2022. The experiment was laid out in Randomized Block Design with seven different treatments viz. T1 = Pre-emergence application of Pendimethalin @ 6 ml /L, T2= Post emergence application of Quizalofop-ethyl @ 0.040 kg/ha ,T3 = Pre-emergence application of pendimethalin @ 6 ml/L + one hand weeding at 40 DAS , T4 = Post emergence application of Quizalofop-ethyl @ 0.040 kg ha-1 at 25 DAS + one hand weeding , T5 = Pendimethalin @ 6 ml /L as pre-emergence + Quizalofop-ethyl @ 0.040 kg ha-1 at 25 DAS , T6 = Weed free check (Three hand weeding) 20, 40 and 60 DAS , T7 = weed check control replicated thrice. The result of the study revealed that at 30 DAS maximum plant height (30.96cm) was reported in treatment T3 : Pre-emergence application of Pendimethalin @ 6 ml/L + one hand weeding at 40 days of sowing whereas at 60 and 90 DAS maximum plant height (75.50 and 113.53 cm) was reported in T6 : Weed free check (Three hand weeding) 20, 40 and 60 DAS. Maximum number of branches per plant (4.60)at 60 DAS was found in T3 : Pre-emergence application of Pendimethalin @ 6 ml/L + one hand weeding at 40 DAS and 90 DAS maximum number of branches per plant (5.86) was reported in T6 : Weed free check (Three hand weeding) 20, 40 and 60 DAS. Maximum number of nodes (17.83 ) at 60 days after sowing was noticed in treatment T3 = Pre-emergence application of Pendimethalin @ 6 ml/L + one hand weeding at 40 DAS and 90 Days after of sowing maximum number of nodes () was in treatment T6 = Weed free check (Three hand weeding) 20, 40 and 60 DAS. Maximum Pod diameter( 1.74cm) , fruit weight (12.88gm ), pod length( 14.1cm) , number of pods per plant( 25.66 ) , pod yield per plant ( 304.73gm) , pod yield per hectare (16.91 t), TSS( 3.2 Brix), crude fibre (8.46%) and cholorophyll content (1.18 mg) and relative cholorophyll content (54.39) .
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The present study entitled “Potential of Zinc glycinate and Calcium chloride on morphological and yield characters of Wheat (Triticum aestivum L)” was carried out to assess the effectof seed treatments during 2022-2023 to find the suitable seed treatment for wheat. Thirteen treatments along with control consists of Calcium chloride, Zinc glycinate and Calcium chloride & Zinc Glycinate in different concentrations, individually and combination as well. A Randomized Block Design (RBD) was used for statistical analysis. The main objectives of this experiment was to evaluate the influence of different concentrations of Zinc glycinate and Calcium chloride on morphological and yield parameters of Wheat and to determine the effective treatment for wheat. The results indicated that all treatments recorded significant variation for pre-harvest and post-harvest parameters that were studied. The treatment T12 (Calcium chloride + Zinc glycinate-7%+7%) significantly recorded the higher values in Field emergence(95.55%), Plant height(93.13 cm), Number of tillers per plant(5.73), Spike length(15.18 cm), Seed yield per plant(16.37g) and Harvest Index(40.09%), in comparision with other treatments and lowest recorded in T0(control). This study helps to find the best suitable seed treatment for wheat.
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Seed hardening refers to different processes that involve treating seeds to enhance their resilience, break seed dormancy and improve their chances of successful germination and plant establishment during harsh conditions. Seeds are soaked in the solutions of KCl, NAA, KNo3 and CaCl2 to break dormancy increase the germination percentage and improve plant morphological parameters in linseed. The experiment was carried out for “Effect of seed hardening on seed germination and morphological parameters in Linseed (Linum usitatissimum L),, during Rabi season in the year 2022 at Field Experimentation Centre, Department of Genetics and Plant Breeding, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, Technology And Sciences, Prayagraj, Uttar Pradesh on linseed crop. The experiment was laid out in Randomized Complete Block Design (RCBD) with 13 treatments and 3 replications. T0-Control, T1-NAA-25 ppm, T2-NAA-50 ppm, T3-NAA-150 ppm, T4-KCl-25 ppm, T5-KCl-50 ppm, T6-KCl-150 ppm, T7-KNo3-25 ppm, T8-KNo3-50 ppm, T9-KNo3-150 ppm, T10-CaCl2-25 ppm, T11-CaCl2-50 ppm, T12-CaCl2-150 ppm were the treatments. Linseed seeds were treated with NAA, KCl, KNo3 and CaCl2 with different concentrations (25 ppm,50 ppm and 150 ppm) for 5 hours and after sowing growth, yield and yield parameters were observed. The main objectives are to determine the effect of seed hardening on seed germination and morphological characteristics of Linseed and to find out the suitable concentration for seed hardening in Linseed. It was noticed that T9-KNo3-150 ppm treatment performed better significantly different at a 5% level of significance, when compared with other treatments where a minimum was observed in control. The highest germination percentage (92.20%), plant height (74.34 cm), number of primary branches (3.87), number of secondary branches (23.53), seeds per capsule (8.13), seed yield per plant (3.42) and harvest index (25.38%) showing better results when treated with treatment (T9)-KNo3-150 ppm for 5 hours and followed by Treatment(T11) CaCl2-50 ppm. Very less days (72) required for 50% flowering and maturity (111.67) were observed in treatment T9 when compared with other treatments. It concluded that T9(KNo3-150 ppm) was superior in all the growth and yield parameters in linseed. So we recommended that treatment T9 is the best seed hardening treatment for linseed according to this experiment.
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The present investigation contains seven different treatments viz., weedy check (control), weed free check (3 hand weeding) (first hand weeding at 25 DAS), pre-emergence application of Pendimethalin @ 6ml/L, pre-emergence application of Pendimethalin @ 6ml/L + one hand weeding, pre- emergence application of Pendimethalin @ 6ml/L + post emergence @ 40-50 g/ha at 25 DAS, post-emergence application of Metribuzin @ 525g/ha at 25DAS and post-emergence spray of Imazethapyr @ 100 g ai/ha at 25 DAS replicated thrice. The cowpea variety ‘Kashi Kanchan’ was used in experiment. Results of the experiment revealed that though, the weed free check (T2) recorded zero weed population and slightly higher values of growth and yield parameters but among tested treatments, pre-emergence application of Pendimethalin @ 6ml/L + one hand weeding (T4) and pre-emergence application of Pendimethalin @ 6ml/L + Quizalofop ethyl @ 40-50 g/ha at 25 DAS(T5) significantly reduced weed number (48.12 and 52.18/m2) and produced significantly highest plant height (47.30 and 45.98 cm), pod length (21.64 and 20.86 cm), number of pods/plant (35.94 and 34.18), average pod weight(11.18 and 11.06 g), green pod weight/plant (367.84 and 348.63g), green pod weight/plot (11.24 and 10.54 kg) and green pod yield per hectare(118.96 and 111.55q). However, these three treatments (T2, T4 and T5) were statistically at par with each other in terms of growth and yield parameters.Hence, these two weed management practices (T4 and T5) may serve as alternative of manual weeding and may be recommended for farmers of the central plain zone of Uttar Pradesh for higher returns from vegetable cowpea crop.
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The tobacco caterpillar, Spodoptera litura (Fabricius) is present as an economically important and regular polyphagous pests in India and other countries. The knowledge of biology and ecology of an insect pests is a prerequisite for its management. An experiment was conducted on biology of Spodoptera litura (Fabricius) on different host plants in laboratory of the Department of Entomology, Rajasthan College of Agriculture, Maharana Pratap University of Agriculture and Technology, Udaipur, Rajasthan. The results revealed that the minimum and maximum incubation period of S. litura was 2.98 and 3.30 days recorded on castor and cauliflower, respectively. The minimum larval and pre pupal period was 12.96 and 1.00 days recorded on castor. The minimum and maximum pupal period were recorded on cotton (8.27 days) and cauliflower (6.44 days), respectively. The adult male and female moth survival maximum larvae reared on cauliflower 5.00 and 6.90 days whereas minimum on castor 3.95 and 6.00 days, respectively. The maximum percent adult emergence was recorded larvae reared on castor (87.50%) followed by cauliflower (85.00%) whereas minimum on cotton (67.50%). The maximum fecundity was recorded on castor (886.25) followed by soybean (870.00). The entire minimum life cycle was recorded on castor (29.05 days) whereas maximum on cotton (36.50days) followed by soybean (34.24 days). It was concluded that castor is best host plant for S. litura.
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RESUMEN Objetivo: Identificar los factores asociados al delirio de emergencia en niños en la Unidad de Recuperación Posanestésica de un Instituto Especializado en Salud Pediátrica del Perú. Métodos: Se realizó un estudio transversal en niños de 2 a 6 años, clasificación del estado físico I y II, en procedimientos electivos bajo anestesia entre septiembre y diciembre 2022. La variable principal fue la presencia de delirio de emergencia evaluada con la escala Pediatric Anesthesia Emergence Delirium mayor o igual a 10 puntos. Para identificar los factores asociados con el delirio, se aplicó el modelo de regresión de Poisson y se consideró significativo un valor p < 0,05. Resultados: De los 150 niños, se encontró que la incidencia de delirio de emergencia se presentó en el 10,6%. De ellos, el 81,4% fueron menores de 5 años, el dolor se asoció significativamente en el 37,5% con RP = 3,63, IC95% [1,20, 10,1] y se observó que el 68,8% necesitó cuidados paliativos. Conclusiones: El dolor se asoció con el delirio de emergencia posanestésico en niños. La prevención y el tratamiento del delirio de emergencia deben centrarse en el control del dolor posoperatorio y en la vigilancia cuidadosa de los pacientes después de la cirugía.
ABSTRACT Objective: Identify associated factors with emergence delirium in children in the Post-Anesthetic Recovery Unit of a Pediatric Health Specialized Institute in Peru. Methods: A cross-sectional study was carried out in children from 2 to 6 years old, physical status classification I and II, in elective procedures under anesthesia. The main variable was the presence of emergence delirium evaluated with the Pediatric Anesthesia Emergence Delirium scale greater than or equal to 10 points. To identify the factors associated with delirium, the Poisson regression model was applied and a p value < 0.05 was considered significant. Results: Of the 150 children, it was found that the incidence of emergence delirium occurred in 10.6%. Of these, 81.4% were under 5 years of age, pain was significantly associated in 37.5% with PR = 3.63, 95%CI [1.20, 10.1] and it was observed that 68, 8% required palliative care. Conclusion: Pain was associated with delirium of postanesthetic emergence in children. Prevention and treatment of emergence delirium should focus on postoperative pain control and careful monitoring of patients after surgery.
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Among the Kharif legumes clusterbean (Cyamopsis tetragonoloba L. Taub) is important crop and popularly known as “Guar” in India. A field experiment was conducted during Kharif 2013 at Agronomy Farm, S.K.N. College of Agriculture, Jobner, Jaipur (Rajasthan) to evaluate the weed management in clusterbean under the application of different agrochemicals and phosphorus levels. The treatments comprising 6 weed control treatments (Weedy check, one hand weeding at 20 DAS, two hand weeding at 20 and 40 DAS, pendimethalin at 0.75 kg/ha, imazethapyr at 100 g/ha and fenoxoprop-p-ethyl at 70 g/ha and four levels of phosphorus (0, 20, 40 and 60 kg/ha) assigned to main and sub plots of spilt plot design, respectively and replicated thrice. Results showed that HW twice at 20 and 40 DAS and pre emergence application of imazethapyr at 100 g/ha resulted significant reduction in weed density and weed dry matter in comparison to most of the treatments. Results further indicated that application of 60 kg P2O5/ha in clusterbean recorded the highest density and dry weight of weeds at all the stages. Maximum weed control efficiency was recorded under two hand weeding at 20 & 40 DAS.
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A field experiment with the objectives to understand the evaluation of mulching effects on weed control in blackgram production under irrigated condition involving two factors viz., mulching (paddy straw mulching, sugarcane trash mulching, no mulching) and herbicidal treatments (pendimethalin pre-emergence (PE) @ 1.0 Kg/ha, pendimathalin + Imazethapyr (pre-mix) pre-emergence Valor 32% EC 1.0 Kg/ha, Hand weeding on 15 and 30 days after sowing, weedy check) was undertaken in Factorial Randomized Block Design (FRBD) design with three replications at the instructional farm of Karunya Institute of Technology and Sciences, Coimbatore region of western Tamil Nadu during the cropping seasons of Rabi 2022-23. Results revealed that paddy straw mulching sequential application of Pendimathalin + Imazethapyr (pre-mix) pre-emergence Valor 32% EC and sugarcane trash mulching sequential application of pendimathalin + imazethapyr (pre-mix) pre-emergence Valor 32% EC recorded lower weed density, weed dry weight and maximum crop yield as well as net returns over rest of the mulching and herbicidal treatments.
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Wheat (Triticum aestivum) is a globally significant crop and a staple food for millions of people. Weed infestation is one of the major constraints affecting wheat productivity worldwide. The purpose of this study was to assess the efficiency of Carfentrazone ethyl 5% + Clodinafop propargyl 15% DF as a post-emergence herbicide against predominant weeds in wheat crops. Wheat is a globally significant crop and a staple food for millions of people. Weed infestation is a major constraint affecting wheat productivity. The study was conducted using a Randomized Block Design with three replications and a total of 11 treatments. The herbicide treatments were applied using foliar spray at different doses. Weed control efficiency was evaluated at 30, 45, and 60 days after herbicide application.The results showed that the highest weed control efficiency was observed in the weed-free plot, followed by the treatment with Carfentrazone ethyl 5% + Clodinafop propargyl 15% DF at a dose of 800 g/ha. This treatment provided significant control against different weed species such as Phalaris minor, Avena ludoviciana, and Chenopodium album. The herbicide treatments showed varying degrees of control efficiency, with some treatments performing better than others.These findings highlight the importance of weed management for increasing wheat crop production. The judicious use of herbicides, such as Carfentrazone ethyl 5% + Clodinafop propargyl 15% DF, can effectively control weeds and contribute to higher yields. However, further research and field trials are necessary to optimize the herbicide application and determine its long-term effects on wheat crops. Overall, this study emphasizes the need for effective weed control strategies to enhance wheat productivity and meet the demands of a growing population.
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Introduction: Pediatric postoperative delirium is a frequent complication for which preventive pharmacological measures have been suggested. The use of midazolam as a prophylactic strategy has not yet been thoroughly assessed. Notwithstanding the fact that it is used in pediatric presurgical separation anxiety, its role in delirium is yet to be established. Objective: To quantify the incidence of pediatric postoperative delirium in patients undergoing low risk surgical interventions, exposed to oral midazolam-based premedication and to explore the protective and risk factors associated with the development of delirium. Methods: Prospective, analytical observational study with a cohort design. Children were conveniently selected in accordance with the daily list of surgical procedures in the operating rooms. The inclusion criteria were children between 2 and 10 years old, ASA I-II, undergoing low risk surgeries. Concurrent and longitudinal follow-up was then conducted upon admission to the post-anesthesia care unit (PACU) for the first hour. Results: A total of 518 children were included. The overall incidence of delirium was 14.4 % (95 % CI: 11.4 %-17.5 %). In the subgroup exposed to midazolam, 178 children were analyzed, with an incidence of delirium of 16.2% (95% CI of 10,8 %-21,7). These patients exhibited a higher tendency to delirium with the use of sevoflurane or fentanyl, and/orwhen presenting with severe postoperative pain. Patients exposed to propofol and/or remifentanil showed lower incidences. Conclusions: No reduction in the incidence of emergency pediatric delirium associated with the use of pre-surgical oral midazolam in low risk surgical procedures. Prospective controlled trials and additional research are required to study the effectiveness and safety of this intervention.
Introducción: El delirio pediátrico posoperatorio es una complicación frecuente para la cual se han sugerido medidas farmacológicas de prevención. El uso de midazolam como estrategia profiláctica aún no ha sido suficientemente evaluado. A pesar de que se emplea para la ansiedad de separación pediátrica prequirúrgica, su papel en delirio aún no se ha establecido. Objetivo: Cuantificar la incidencia de delirio pediátrico posoperatorio en pacientes sometidos a cirugías de bajo riesgo quirúrgico, expuestos a premedicación basada en midazolam oral y adicionalmente, explorar los factores protectores y de riesgo asociados a la ocurrencia. Materiales y métodos: Estudio observacional analítico prospectivo con un diseño de cohorte. Se seleccionaron niños por conveniencia de acuerdo con la lista quirúrgica diaria en salas de cirugía. Como criterios de inclusión se tomaron sujetos entre 2 y 10 años de edad, ASA 1-11, sometidos a cirugías de bajo riesgo quirúrgico. Posteriormente se realizó seguimiento concurrente y longitudinal al ingreso a la unidad de recuperación posanestésica (UCPA) durante la primera hora de estancia. Resultados: Se incluyeron 518 niños. La incidencia global de delirio fue del 14,4 % (IC 95 %;11,4 %-17,5 %). En el subgrupo expuesto a midazolam se analizaron 178 niños, quienes presentaron una incidencia de delirio del 16,2 % (IC 95 %;10,8 %-21,7 %). Estos pacientes presentaron una mayor tendencia a delirio con el uso de sevofluorano o fentanilo, y/o cuando presentaron dolor severo posoperatorio. Pacientes con exposición a propofol y/o remifentanilo exhibieron incidencias inferiores. Conclusiones: No se encontró una reducción en la incidencia de delirio pediátrico de emergencia asociada al empleo de midazolam oral prequirúrgico en cirugías de bajo riesgo. Se requieren estudios prospectivos controlados e investigación adicional para el estudio de la efectividad y seguridad de esta intervención.
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Purpose: Emergency delirium (ED), a common postoperative neurologic complication, causes behavioral disturbances leading to self?traumas and also has long?term adverse effects in children. Our aim was to investigate the efficacy of a single?bolus dose of dexmedetomidine in reducing the incidence of ED. Additionally, pain relief, number of patients who needed rescue analgesia, hemodynamic parameters, and adverse events were assessed. Methods: One hundred and one patients were randomly allocated into two groups: 50 patients received 15 mL of dexmedetomidine 0.4 ?g/kg (group D) and 51 patients received volume?matched normal saline (group C). Hemodynamic parameters such as heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were monitored regularly throughout the procedure. ED was assessed with Pediatric Anesthesia Emergence Delirium Scale (PAEDS), and pain was measured using the modified Objective Pain Score (MOPS). Results: The incidences of ED and pain were higher in group C than group D (P < 0.0001 and P < 0.0001, respectively). Group D showed significant decrease in MOPS and PAEDS values at 5, 10, 15, and 20 min (P < 0.05), HR at 5 min (P < 0.0243), and SBP at 15 min (P < 0.0127). There was no significant difference in DBP between the two groups at any time point. The mean blood pressure (MBP) at 10 min was significantly less in group D than group C (P < 0.001). Conclusion: Dexmedetomidine 0.4 ?g/kg as a single bolus over 10 min immediately after intubation is effective for the prevention of ED and significantly reduces the need of rescue analgesia without compromising the hemodynamic parameters in children undergoing ophthalmic surgery.