ABSTRACT
OBJECTIVE@#In this paper, the key points of quality control and safety evaluation of human assisted reproductive medium were summarized to provide reference for the establishment of relevant standards and quality control in the future.@*METHODS@#Through literature research, the key factors of quality control and risk control of human assisted reproductive medium were summarized, and the problems in clinical transformation were discussed.@*RESULTS@#It is very important for the development of human assisted reproduction technology to study the active ingredients and their harmful degradation products and drugs in the culture medium of assisted reproduction.@*CONCLUSIONS@#At present, the biggest challenge is to effectively control the quality of the culture medium for human assisted reproduction, establish corresponding inspection methods and quality standards for the key components, ensure the safety and effectiveness during the product shelf life, and thus improve the success rate of human assisted reproduction technology.
Subject(s)
Humans , Quality Control , Reproduction , Reproductive Techniques, AssistedABSTRACT
Objective To explore the relationship between clinical outcomes and embryo transfer number, and to provide some proposals for transfer selection of elderly patients. Methods Data from 80 fresh transfer cycles with cleavage-stage embryos were analyzed. Cycles were divided into several groups according to transfer number. Clinical pregnancy rate, implantation rate, multiple pregnancy rate and live birth rate were compared. Results To women no younger than 38 years old, when available embryo number was larger than two, similar clinical outcomes could be achieved by transferring two and three embryos. This trend was independent of the number of transferred 8-cell embryos. Conclusion The number of fresh cleavage-stage embryos transfer should not exceed two in elderly women.
ABSTRACT
A utilização das técnicas de reprodução assistida vem possibilitando, nas últimas décadas, a realização da vontade de exercer a parentalidade em diferentes contextos e situações, muito além da infertilidade. Aqui são elaboradas reflexões associadas à monoparentalidade buscada, não acidental, considerando contingências específicas, tais como a utilização de sêmen post mortem e a denominada produção independente, seja em indivíduos hétero ou homossexuais. Tais reflexões são eliciadas em virtude da prática clínica à luz da revisão de literatura e debruçam-se sobre as condições que favorecem essa busca, muitas vezes de caráter narcísico e que necessitam de uma escuta e uma interlocução privilegiada no atendimento clínico...
In the last decades, the use of assisted reproduction techniques has favored the fulfillment of parenthood desires indifferent contexts and situations, beyond infertility it self. This paper discusses issues related to programmed single parenthood eagerly sought in specific situations, such as the use of post mortem semen and the so-called independentproduction among hetero and homosexual individuals. This reflexion is brought by the authors clinical experienceand addresses the conditions that favor this perhaps narcissistic search, which needs a specialized hearing and exchangewithin the clinical context...