ABSTRACT
Dog ear is very important because of disease vulnerability. Therefore, gross anatomy and sectional anatomy on CT and MRI of the dog ear should be mastered by veterinarian. The purpose of this research was to present the digital atlases which high quality sectioned images and 3D models of detailed structures of dog ear could be displayed freely. In the sectioned images of a female beagle, ear structures were reconstructed by surface modeling to make 3D models. The sectioned images and 3D models were put into the browsing software and PDF file, respectively. Using the browsing software and the PDF file, gross and radiological anatomy of dog ear could be learned easily and accurately. The auditory tube of a dog was placed anterior to the tympanic cavity unlike human. The tensor tympani muscle of a dog was connected to the dorsal wall of the tympanic cavity with the malleus. No remarkable difference in the auditory ossicles, semicircular ducts, facial nerve, and endolymphatic duct was observed between dogs and humans. The software and the PDF file will be provided to other researchers freely to help contribute to veterinary research and education.
La oreja del perro es importante debido a la vulnerabilidad de enfermedad. Por lo tanto, el veterinario debe conocer plenamente la anatomía macroscópica y la anatomía seccional en la TC y la RM del oído del perro. El objetivo de esta investigación fue presentar los atlas digitales que podían mostrar imágenes seccionadas de alta calidad y modelos 3D de estructuras detalladas de orejas de perro. En las imágenes seccionadas de una hembra Beagle, las estructuras de las orejas se reconstruyeron mediante modelado de superficie con el objetivo de crear modelos 3D. Las imágenes seccionadas y los modelos 3D se colocaron en un software de navegación y un archivo PDF. El uso de software de navegación y el archivo PDF permiten un aprendizaje fácil y preciso de la anatomía macroscópica y radiológica de la oreja de perro. El músculo tensor del tímpano de un perro estaba conectado a la pared dorsal de la cavidad timpánica con el martillo. No se observaron diferencias notables en los huesecillos auditivos, los conductos semicirculares, el nervio facial y el conducto endolinfático entre perros y humanos. El software y el archivo PDF estarán disponibles libremente para los investigadores para ayudar en la investigación y educación veterinaria.
Subject(s)
Animals , Dogs , Ear/diagnostic imaging , Software , Anatomy, Cross-Sectional , Imaging, Three-Dimensional , Ear/anatomy & histology , Visible Human Projects , Ear Auricle/diagnostic imagingABSTRACT
To allow students and surgeons to learn the sites for botulinum toxin injection, new types of educational images are needed because MRI, CT, and sectioned images are inadequate. This article describes browsing software that displays face peeled images that allow layers along the curved surface of the face to be peeled gradually in even depths across the surface. Two volume models of the head were reconstructed from sectioned images and segmented images of Visible Korean, respectively. These volume models were peeled serially at a thickness of 0.2 mm along the curved surface of the facial skin to construct the peeled images and peeled segmented images. All of the peeled images were marked with botulinum toxin injection sites, facial creases and wrinkles, and fat compartments. All peeled images and the text information were entered into browsing software. The browsing software shows 12 botulinum toxin injection sites on all peeled images of the anterior and lateral views. Further, the software shows 23 anatomic landmarks, 13 facial creases and wrinkles, and 7 face fat compartments. When a user points at any structure on the peeled images, the name of the structure appears. Our software featuring the peeled images will be particularly effective for helping medical students to quickly and easily learn the accurate facial anatomy for botulinum toxin injection sites. It will also be useful for explaining plastic surgery procedures to patients and studying the anatomic structure of the human face.
Para permitir que los estudiantes y cirujanos aprendan los sitios para la inyección de toxina botulínica, se necesitan nuevos tipos de imágenes educativas ya que las imágenes de MRI, CT e imágenes seccionadas son inadecuadas. Este artículo describe el software de navegación que muestra imágenes de cara sin piel que permiten que las capas a lo largo de la superficie curva de la cara se despeguen gradualmente en profundidades uniformes a lo largo de la superficie. Se reconstruyeron dos modelos de volumen de la cabeza a partir de imágenes seccionadas e imágenes segmentadas visibles, respectivamente. En estos modelos de volumen se retiró la piel en serie con un grosor de 0,2 mm a lo largo de la superficie curva de la cara para construir las imágenes sin piel y las imágenes segmentadas sin piel. Todas las imágenes sin piel se marcaron con puntos de inyección de toxina botulínica, arrugas y arrugas faciales y compartimientos de grasa. Todas las imágenes despegadas y la información de texto se ingresaron en el software de navegación. El software de navegación muestra 12 sitios de inyección de toxina botulínica en todas las imágenes de las vistas anterior y lateral. Además, el software muestra 23 puntos de referencia anatómicos, 13 pliegues y arrugas faciales y 7 compartimentos de grasa facial. Cuando un usuario selecciona cualquier estructura en las imágenes sin piel, aparece el nombre de la estructura. Nuestro software con las imágenes sin piel será particularmente efectivo para ayudar a los estudiantes de medicina a aprender rápida y fácilmente la anatomía facial precisa para los sitios de inyección de toxina botulínica. También será útil para explicar los procedimientos de cirugía plástica a pacientes y estudiar la estructura anatómica del rostro humano.
Subject(s)
Humans , Surgery, Plastic/education , Visible Human Projects , Face/anatomy & histology , Botulinum Toxins , Cadaver , Image Interpretation, Computer-Assisted , Color , Anatomic Landmarks , Models, AnatomicABSTRACT
BACKGROUND: Gross anatomy and sectional anatomy of a monkey should be known by students and researchers of veterinary medicine and medical research. However, materials to learn the anatomy of a monkey are scarce. Thus, the objective of this study was to produce a Visible Monkey data set containing cross sectional images, computed tomographs (CTs), and magnetic resonance images (MRIs) of a monkey whole body. METHODS: Before and after sacrifice, a female rhesus monkey was used for 3 Tesla MRI and CT scanning. The monkey was frozen and sectioned at 0.05 mm intervals for the head region and at 0.5 mm intervals for the rest of the body using a cryomacrotome. Each sectioned surface was photographed using a digital camera to obtain horizontal sectioned images. Segmentation of sectioned images was performed to elaborate three-dimensional (3D) models of the skin and brain. RESULTS: A total of 1,612 horizontal sectioned images of the head and 1,355 images of the remaining region were obtained. The small pixel size (0.024 mm × 0.024 mm) and real color (48 bits color) of these images enabled observations of minute structures. CONCLUSION: Due to small intervals of these images, continuous structures could be traced completely. Moreover, 3D models of the skin and brain could be used for virtual dissections. Sectioned images of this study will enhance the understanding of monkey anatomy and foster further studies. These images will be provided to any requesting researcher free of charge.
Subject(s)
Female , Humans , Anatomy, Cross-Sectional , Brain , Dataset , Haplorhini , Head , Macaca mulatta , Magnetic Resonance Imaging , Primates , Skin , Tomography, X-Ray Computed , Veterinary MedicineABSTRACT
BACKGROUND: The sectioned images of a cadaver head made from the Visible Korean project have been used for research and educational purposes. However, the image resolution is insufficient to observe detailed structures suitable for experts. In this study, advanced sectioned images with higher resolution were produced for the identification of more detailed structures. METHODS: The head of a donated female cadaver was scanned for 3 Tesla magnetic resonance images and diffusion tensor images (DTIs). After the head was frozen, the head was sectioned serially at 0.04-mm intervals and photographed repeatedly using a digital camera. RESULTS: On the resulting 4,000 sectioned images (intervals and pixel size, 0.04 mm³; color depth, 48 bits color; a file size, 288 Mbytes), minute brain structures, which can be observed not on previous sectioned images but on microscopic slides, were observed. The voxel size of this study (0.04 mm³) was very minute compared to our previous study (0.1 mm³; resolution, 4,368 × 2,912) and Visible Human Project of the USA (0.33 mm³; resolution, 2,048 × 2,048). Furthermore, the sectioned images were combined with tractography of the DTIs to elucidate the white matter with high resolution and the actual color of the tissue. CONCLUSION: The sectioned images will be used for diverse research, including the applications for the cross sectional anatomy and three-dimensional models for virtual experiments.
Subject(s)
Female , Humans , Anatomy, Cross-Sectional , Brain , Cadaver , Diffusion , Diffusion Tensor Imaging , Head , White MatterABSTRACT
The human quest to master the anatomy and physiology of living systems started as early as 1600 BC, with documents from the Greeks, Indians, and Romans presenting the earliest systematic studies and advances. Following the fall of the Roman Empire, the progress slowed until the Renaissance renewed scientific interest in anatomy and physiology, ushering in an era of spectacular advances. Alongside the discoveries of modern science, innovations in media such as printing, photography and color reproduction, improved the accuracy of communicating science. Techniques for noninvasively viewing the human body, such as magnetic resonance imaging, opened up new ways of exploring and understanding anatomy, physiology, and disease pathogenesis. Advances in three-dimensional (3D)-technologies, including computer graphics and animation are directly linked to many advances in medicine and surgery. Anatomy education has come a long way from papyrus leaf inscriptions to computerized 3D modeling, holographic representation, and virtual reality-based software. The future presents unlimited options for studying and understanding anatomy as Google glasses, bioprinting, virtual reality, and allied technologies transform the world into a classroom. This review summarizes the journey of mankind to master anatomy and physiology.
Subject(s)
Humans , Bioprinting , Computer Graphics , Education , Eyeglasses , Glass , Human Body , Magnetic Resonance Imaging , Photography , Physiology , Reproduction , Roman WorldABSTRACT
The objective of this research was to present high-quality sectioned images of a whole female body which would be helpful in creating an atlas, virtual dissection, and various applications for medical education and clinical trial. In addition, the authors sought to demonstrate the applicabilities of sectioned images. A female cadaver was ground serially using the cryomacrotome and photographed to make the sectioned images. Structures in the images were segmented to produce segmented images in Photoshop. In the self-developed browsing software, the sectioned and segmented images were stored. Based on the segmented images, surface models were built on commercial software and saved as PDF file. High-quality sectioned images of the female body were taken (intervals, 0.2 mm or 1 mm; pixel size, 0.1 mm; color depth, 48 bit color). In the images obtained, very small and complicated structures could be identified in color of living body. In order to ascertain the applicability of the images, the browsing software including sectioned and segmented images and the PDF file including surface models were produced. The sectioned images and surface models produced during this research will prove to be a useful source for medical software. All data generated is available free of charge.
El objetivo fue presentar imágenes seccionadas en alta calidad de un cuerpo femenino que sería de gran ayuda en la creación de un atlas, en la disección virtual y en diversas aplicaciones para la educación médica y los ensayos clínicos; además, se trata de demostrar la aplicabilidad de las imágenes seccionadas. Un cadáver de sexo femenino fue seccionado en serie utilizando un criomicrótomo y luego fue fotografiado. Las estructuras en las imágenes fueron segmentadas para producir imágenes en Photoshop. En un programa de navegación de desarrollo propio se almacenaron las imágenes seccionadas y segmentadas. Basado en las imágenes segmentadas, los modelos de superficie fueron construidas en el programa y guardadas como archivo PDF. Las imágenes seccionadas de alta calidad del cuerpo femenino fueron tomadas con intervalos entre 0,2 o 1 mm; tamaño en píxeles de 0,1 mm y profundidad de color de 48 bits). En las imágenes obtenidas, las estructuras muy pequeñas y complicadas pudieron ser identificadas a color en el cuerpo. Con el fin de determinar la aplicabilidad de las imágenes, se produjo un programa de navegación que incluye imágenes seccionadas y segmentadas y el archivo PDF que incluye modelos de superficie. Las imágenes seccionadas y los modelos de superficie producidos durante esta investigación demostraron ser una fuente útil como programa médico. Todos los datos generados se encuentran disponibles gratuitamente.
Subject(s)
Humans , Female , Adult , Anatomy, Cross-Sectional , Imaging, Three-Dimensional , Whole Body Imaging , Cadaver , Republic of Korea , Visible Human ProjectsABSTRACT
Digitized Virtual Human is a new scientific name for most of us, so it is necessary to elucidate its scientific meanings, general situation, research actuality and future prospect. Remarkable benefits have been obtained from Visible Human Project (VHP) in the United States of America, and it has progressed into the research field concerning virtual physical human and physiome. It is a cutting edge scientific field combining life science and information technology in research on visible, virtual and controllable human body. There is an immense amount of indepth theories and technologies to be explored before it is practically mature. Whereas it is very valuable for medical research. Problems in regard to Virtual Chinese Human (VCH) were discussed in 174th Xiang Shan Scientific Conference which was held in 2001, and then the research on VCH formally inargurated in China. The research project has been in rapid progress, and up to now, there are already four datasets reported in our country since then. Image processing and virtual reality technology applied in Visible Human have been in sound development. In the future research, we should pay attention to the quality of dataset and the pertinence of application.