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ObjectiveBased on knowledge mapping， the studies on prediction models in the field of traditional Chinese medicine （TCM） were visually analyzed， which provided a reference basis for the excavation and evolution of the future research direction by combing the development process and summarizing the research hotspots and dynamic trends. MethodChina National Knowledge Infrastructure and Web of Science Core Collection databases were searched to obtain studies on prediction models in the field of TCM from inception to February 28， 2023. Endnote X20 software was used for document management. Knowledge mapping generated by CiteSpace software and VOSviewer software was used to visually analyze the characteristics of publication， institutional cooperation relationship， author cooperation network， co-citation， and keywords. ResultA total of 264 pieces of Chinese literature and 266 pieces of English literature were included， and the overall number of research publications showed an increasing trend year by year. The cooperation relationship between the issuing institutions showed obvious regional characteristics， with the closest cooperation relationship between the universities of TCM and their affiliated hospitals， as well as secondary units subordinate to scientific research institutions. The number of research teams and team members publishing papers in English was higher， and cooperation between different teams was more frequent. Groundbreaking and/or referential studies were widely cited and referred to. The highly cited literature was mainly published in complementary and alternative medicine journals and pharmaceutical journals. Research hotspots mainly focused on clinical prediction models of TCM， quantitative models of TCM， and specific modeling methods. The application of artificial intelligence technologies such as machine learning and deep learning in the field of TCM will be the most cutting-edge research direction in the future. ConclusionThe field of TCM is paying more and more attention to the studies on prediction models， while the research cooperation mode involving multiple organizations and teams has increasingly become the mainstream. With the continuous development of multi-disciplinary integration， studies on prediction models are closely related to the development and rise of innovative techniques and methods， and any breakthrough in theory or application will induce and guide a new round of research upsurge. Systematic reviews of topic-specific prediction models should be carried out in the future to provide evidence-based evidence.
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BACKGROUND:To investigate the research focus and follow-up research trend of exosomes in the diagnosis and treatment of chronic kidney disease,in order to provide a corresponding reference basis for the future research of exosomes in the diagnosis and treatment of chronic kidney disease,and promote the development of this field. OBJECTIVE:To conduct a bibliometric analysis of relevant studies in each database painstakingly until now for public publication on exosome diagnosis and treatment of chronic kidney disease,to explore the current state and trend of the field in this discipline,and to predict future research directions. METHODS:A computerized search was performed on WanFang,CNKI,CBM,VIP,Web of Science,Cochrane Library,PubMed,and Embase databases from inception to December 2022 for published literature related to the diagnosis and treatment of chronic kidney disease by exosomes.The literature transcripts were screened by NoteExpress for co-occurrence,clustering and mutational analysis among authors,institutions,and keywords through CiteSpace 6.1R4 and VOSviewer software,and the visual knowledge map was plotted. RESULTS AND CONCLUSION:(1)A total of 804 articles,including 133 in Chinese and 671 in English,were included,and the volume of publications climbed year by year with a rapid trend.We included 3 649 literature authors,including 326 Chinese authors and 3 323 English authors,and the field has formed a core team centered on scholars such as Liu Bicheng,Wang Bin,Lyu LinLi,Wang Xiaonan and Wang Haidong,and has formed a stable multicenter collaboration platform among institutions.Research focuses on the three functions of exosomes:carrier,diagnosis and therapy.(2)As a form of extracellular vesicles,exosomes have important mechanisms for carrying,transferring molecular mediators and signal transduction,and have an important role in the physiopathological development of chronic kidney disease,which can provide important health surveillance data for epidemiological studies and clinical decision-making.In recent years,the development of relevant studies on exosome-based diagnosis of chronic kidney disease has expanded dramatically,forming a development layout of collaborative cooperation among multiple institutions worldwide,led by our scientific research institutions.However,at present,the study of the specific function and mechanism of action of exosomes and contents in the disease process has not been fully validated.Their significance for the early diagnosis and prognosis evaluation of chronic kidney disease is not very clear.The intrinsic mechanism of action-related research is still relatively poor.Isolation and purification techniques still need to be improved,and high-quality evidence-based clinical trials with multicenter and large samples have not yet appeared,which still need to be verified by further studies.
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BACKGROUND:Bibliometrics and visual analyses based on thematic literature are particularly important for understanding the foundation and frontiers of postmenopausal osteoporosis research. OBJECTIVE:To perform bibliometric,citation,and visualization analyses of highly cited SCI papers in postmenopausal osteoporosis research over the last 20 years. METHODS:The top 100 highly cited papers on postmenopausal osteoporosis published between 2003 and 2022 included in SCI-EXPANDED catalog of the Web of Science database were obtained for bibliometric measure and visual analysis using CiteSpace software. RESULTS AND CONCLUSION:The top 100 highly cited papers have a total of 67 377 citations in the Web of Science Core Collection,with an annual average of 49.17 citations per paper.Postmenopausal osteoporosis research primarily involves medical,engineering,biological,and multidisciplinary fields.The subcategories are dominated by endocrinology and metabolism,and medicine:internal medicine.Stable and close cooperative network relationships have been formed globally.United States,University of California System,Cummings,and Steven R are the country,research institution,and author,respectively,with the most highly-cited publications.The frontiers of postmenopausal osteoporosis research mainly include calcium and vitamin D supplementation and fracture risk,clinical studies of bisphosphonates in the treatment of postmenopausal osteoporosis,atypical femur fracture,clinical studies of new drugs and sequential treatment of postmenopausal osteoporosis,predictors of fracture risk,mid-and long-term follow-up of osteoporotic vertebral compression fractures,genetic polymorphisms and hereditary factors,formulation and updating of clinical practice guidelines for postmenopausal osteoporosis.Large cohort studies,high-quality randomized controlled trials,systematic reviews,meta-analyses,and clinical practice guidelines are the great engines that drive the development of clinical research in postmenopausal osteoporosis.We should make efforts in the above areas to improve China's international influence in the field of osteoporosis.
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ObjectiveTo visualize and analyze the researches on transcranial direct current stimulation (tDCS) for stroke rehabilitation. MethodsThe Web of Science core collection and CNKI were searched for literature on the use of tDCS for stroke rehabilitation, since the establishment of the database until March 31st, 2023. The literature was analyzed wtih CiteSapce 6.2.R2 in term of disciplines, articles number, countries, keywords and co-citation, etc. ResultsA total of 732 articles in English and 322 articles in Chinese were included, and the number of articles was on the rise. The country with the largest number of publications was the United States, and the journal with the highest citation frequency was Stroke. The keywords with high attention in recent years were virtual reality, upper limb and transcranial magnetic stimulation. The clustering words of co-cited literature were aphasia, homeostatic plasticity, and motor recovery, etc. ConclusionThe researches about tDCS for stroke rehabilitation are increasing year by year, and the research fields are diversified. The hotspots include rehabilitation for motor and speech, and combination with other therapy, such as repetitive transcranial magnetic stimulation and acupuncture. The combination of tDCS with new rehabilitation protocols such as brain-computer interfaces and virtual reality, as well as the selection of individualized stimulation parameters to construct patient-centered tDCS models may be hot in the future.
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ObjectiveFocusing on digital health literacy， this study elucidated the current research status， focal points， and developmental trends in this field over the past decade through bibliometric analysis and knowledge mapping of relevant papers. MethodsUtilizing software such as CiteSpace and VOSviewer， this study analyzed literature on digital health literacy from 2012 to 2022 retrieved from the Web of Science （WoS） database， employing bibliometric approaches such as keyword co-occurrence， timeline clustering， keyword burst detection， and author collaboration networks. ResultsThe research generally exhibited a continuing upward trend in publication volume； application fields were concentrated in disciplines such as mathematics and medicine； keywords include healthcare， intervention measures， health management， and technological applications. Research in digital health literacy （DHL） has evolved from an early focus on mobile health and behavior change to mid-term focus on health information and internet technology， and more recently to a greater focus on mental health and information technology applications， as well as the application of digital health and mobile technology in health behaviors， reflecting the field’s continuous development towards diversification. ConclusionResearch on digital health literacy is steadily growing and has received widespread recognition and attention from the academic community. With the development of mobile technologies and data science， the field of DHL is expected to make more in-depth research and application breakthroughs in education， scientific research， healthcare， public health， and social welfare.
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ObjectiveTo conduct a visualized analysis of the research related to the use of brain-computer interface technology for stroke rehabilitation in the past ten years, and identify and predict the hot spots and hot trends in order to promote the further development of this field. MethodsThe Web of Science Core Collection database was searched for literature related to brain-computer interface technology for stroke rehabilitation from January, 2011 to October, 2022. CiteSpace 5.8.R3 was used to analyze the number of publications, countries, institutions, authors, keywords, co-citations, and grant support. Results and ConclusionA total of 592 papers were included, and the annual number of publications in this field of research showed a rapid growth trend, and the research enthusiasm continued to increase. The United States was in the leading position in this field, with the highest number of cooperative publications and the highest intermediary centrality; China had certain advantages in this field, but still needed to strengthen the exchange and cooperation with other countries/regions. Foreign institutions and authors had formed a network of close cooperative relationships, and formed a high-impact team represented by Niels Birbaumer, Cuntai Guan, Kai Keng Ang, etc.; there were poor cooperative relationships among domestic authors and institutions, and there were geographical restrictions and lack of high-impact academic groups. The keywords "motor imagery" and "recovery" formed ten major clusters and 15 prominent words with high variation rates, showing a trend of diversification in research directions. The study of the efficacy of upper limb motor rehabilitation and central mechanisms has been the hot topics in this field and will continue for some time in the future; the use of lower limb brain-computer interface systems for improving foot drop, gait and balance in stroke patients and the application of multimodal brain-computer interfaces will probably become a hot topic in the future. Finally, the use of brain-computer interface-guided neurofeedback training for cognitive and language rehabilitation in stroke also needs attention.
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@#Objective To investigate the development, hot spots and trends of event-related potentials for cognitive function research. Methods The literatures about application of event-related potentials in cognitive function research from 2011 to 2021 in CNKI and Web of Science core collection database were retrieved. The countries, authors, institutions, cited reference and keywords were extracted with CiteSpace to draw knowledge mapping. Results The most of researches came from the United States. For China, the author published the most researches was Zhan Xianghong, and the institute was the West China Mental Health Center of Sichuan University; the keywords such as P300 and depression were the most frequent, and researches focused on Alzheimer's disease, depression and schizophrenia, etc., which tended to use negative correlation changes of event-related potentials. Internationally, the author publishing the most researches was christian beste, and the institute was University of California, San Diego. The keywords such as attention and electroencephalograph were the most frequent, and researches focused on Alzheimer's disease and bipolar disorder, etc., which tended to focus on the P300 theta oscillation. Conclusion The application of event-related potential in cognitive function remains heat, to explore the cognitive dysfunction after various diseases.
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@#Objective To evaluate the development, hot spots and trends of the fields of neurogenic bladder.Methods The relevant articles of neurogenic bladder from January, 2000 to June, 2021 in CNKI and Web of Science were retrieved.The countries, authors, institutions, cited reference and keywords were extracted with CiteSpace to draw knowledge mapping. Results and Conclusion A total of 5 064 articles were enrolled. At present, the research on the field of neurogenic bladder is in a stable period of development, and this field has been widely concerned by scholars at home and abroad. The cooperation between domestic authors and institutions is not close enough compared with foreign countries, and domestic cooperation is more between medical schools and their respective affiliated hospitals. In the future, China can further strengthen cross-regional and cross-agency cooperation. Low-frequency electrical stimulation and sacral nerve regulation are seem to be research hotspots, and children's neurogenic bladder and robot-assisted technologies are also needed more attention.
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ObjectiveTo analyze the research status, research hotspots and trends at home and abroad in the field of rehabilitation assistive devices in the past ten years. MethodsThe relevant articles of rehabilitation assistive devices from 2012 to 2021 in CNKI and Web of Science (WoS) core collection database were retrieved. The authors, countries, institutions, research hotspots, and trends were extracted with CiteSpace and VOSviewer to draw knowledge mapping. Results and ConclusionThe annual articles published at home and abroad has shown an upward trend year by year. The team with the most articles in China is the Yu Hongliu team, and the institution with the most articles is China Assistive Devices and Technology Center for Persons with Disablities. The team with the most foreign articles is the Maysam G team, and the institution with the most articles is the University of Pittsburgh. The United States has the largest number of literatures and the highest intermediary centrality. Research hotspots related to rehabilitation assistive devices at domestic and abroad mainly focus on the design and development of rehabilitation assistive device products, the application of rehabilitation assistive devices in special/vulnerable populations, the application effect of rehabilitation assistive devices and related professional services; the development trend of intelligent assistive device product design and application research based on intelligent perception, brain-like computing, deep learning and virtual/augmented reality is predicted.
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Objective:To explore hot spots and trend of medical education quality assurance research in China and provide reference for future research.Methods:We searched the database of CNKI, VIP, Wanfang Database for published studies on quality assurance of medical education research in China. In the form of knowledge mapping, word frequency analysis, social network analysis and cluster analysis were used to explore the research hot spots from the perspective of high frequency keywords. SATI3.2 and Excel tables were used as statistical analysis tools for bibliographic information, the field extraction and word frequency statistics of literature keywords. Using SPSS 20.0, cluster analysis was carried out according to the similarity matrix of high frequency keywords co-occurrence.Results:Totally 249 articles were included in the study and 33 high frequency words were taken into account. The research hot spots of medical education quality assurance in China were divided into four categories: the practical application of medical education quality assurance, the effective methods of medical education quality assurance, the exploration of the construction of medical education quality assurance system, and the management of medical teaching quality assurance.Conclsion:Medical education in our country should perfect the safeguard measures to form characteristic theory framework, explore other methods for medical education quality assurance, establish medical education education quality guarantee system, and strengthen the teaching quality monitoring. The future researches should comply with the national "Double First-rate" construction and the development trend of international medical education, and enhance the research of connotative quality assurance.
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Results and Conclusion:The mean of articles published was 70.5 a year. Germany, USA, UK were the top countries of cooperative documents; Tübingen University, Keio University and Shanghai Jiao Tong University were the top institutions. The most cooperative articles were involved the team of Gharabaghi A. Motor imagery-brain computer interface, network, motor function, especially walking function, may be the focuses in the future. Objective:To summarize the research structure of motor imagery applied in stroke and identify the hotspots and development. Methods:Literatures about motor imagery applied in stroke collected in Web of Science core database between 2010 to 2020 were obtained, and analyzed with CiteSpace software to draw the relevant knowledge mapping of related countries, institutions, authors, and keywords, etc.
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Objective@#To conduct the visualization analysis of literatures about problem-based learning (PBL) teaching in nursing based on the Web of Science database, so as to comprehend the development vein, main research power and knowledge foundation in this field.@*Methods@#The relevant literatures retrieved from Web of Science TM Core Collection were statistically analyzed through the website and uploaded into the CiteSpace software to generate knowledge mapping for visualization analysis.@*Results@#A total of 259 relevant literatures were included and the annual publication volume showed a remarkable rising trend. Among those literatures, the work of Professor Barrows had the biggest influence in this field; the United States was the country with the largest publication; the Hong Kong Polytechnic University had the top publication amount; PBL teaching literatures included by Journal of Advanced Nursing, Medical Education and Nurse Education Today were able to reflect the research foundation of this field to some extent. In addition, our study also found four classic literatures, which discussed the scientific rationality of PBL teaching in nursing education from different angles and had significance for laying foundations.@*Conclusion@#PBL teaching receives more and more attention in nursing education, but high-yielding authors are few, the distribution of national and institutional research power is uneven, and the overall research foundation is relatively weak, which still needs to be further explored.
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Objective To conduct the visualization analysis of literatures about problem-based learning ( PBL ) teaching in nursing based on the Web of Science database , so as to comprehend the development vein, main research power and knowledge foundation in this field. Methods The relevant literatures retrieved from Web of Science TM Core Collection were statistically analyzed through the website and uploaded into the CiteSpace software to generate knowledge mapping for visualization analysis. Results A total of 259 relevant literatures were included and the annual publication volume showed a remarkable rising trend. Among those literatures, the work of Professor Barrows had the biggest influence in this field;the United States was the country with the largest publication; the Hong Kong Polytechnic University had the top publication amount; PBL teaching literatures included by Journal of Advanced Nursing, Medical Education and Nurse Education Today were able to reflect the research foundation of this field to some extent. In addition, our study also found four classic literatures, which discussed the scientific rationality of PBL teaching in nursing education from different angles and had significance for laying foundations. Conclusion PBL teaching receives more and more attention in nursing education, but high-yielding authors are few, the distribution of national and institutional research power is uneven, and the overall research foundation is relatively weak, which still needs to be further explored.
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OBJECTIVE: To investigate the research hotspots of TCM safety and their relationship, so as to promote the improvement of TCM quality, TCM safety management and further research of TCM safety. METHODS: The word frequency analysis was used to study the frequency of keywords and thematic words related to TCM safety, quality and risk in literatures with the help of SATI 3. 2 and Ucinet 6 statistical software. The co-occurrence analysis of high frequency keywords was conducted, and visual network graph of high frequency keywords was drawn on the basis of co-occurrence matrix. The network general characteristics of keywords were analyzed in respects of network density, concentration degree and small-world effect. The network individual characteristics of keywords were analyzed in respects of node centrality, betweenness centrality and closeness centrality, so as to discuss the research thematic hotspots and relevance. RESULTS & CONCLUSIONS: "TCM decoction piece" "processing""TCM quality" "quality management" were main issues and key points of TCM safety research; TCM decoction piece was the most important field, the problems of which mainly reflected in TCM processing. The method and technology of TCM processing influenced TCM safety significantly. It is suggested to establish view of quality, improve the level of TCM safety by means of quality management, quality standard construction and quality control, reduce the risk of TCM safety, improve TCM quality and fully play the role of standard and standardization of Chinese Pharmacopoeia.
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Objective: To analyze the status and existing problems of the diagnostic criteria of qi and yin deficiencysyndrome by applying the knowledge mapping method. Methods: In the China Knowledge Network Database (CNKI), wesearched the relevant journal articles on the diagnostic criteria of qi and yin deficiency syndrome, exported andtransformed the literature data, and used CiteSpace software to draw co-occurrence map of authors, institutions and keywords of research on the diagnosis criteria of qi and yin deficiency syndrome for analysis.Results:A total of 378research papers were included, and the main researchers and teams represented by Li Jiansheng were found.The research institute was mainly the Institute of Geriatrics of Henan University of Traditional Chinese Medicine.Diabetes was the most concerned research direction in this field.Conclusion:Although the research on the diagnostic criteria of qi and yin deficiency syndrome is currently facing great difficulties, the research institutions in this field have cooperat extensively.The wisdom collision brought by such cooperation foundation will provide solutions to these problems, an the output of excellent results was expected.Based on diabetes, IGA nephropathy, coronary heart disease, and clinic research as the method, the relevant research is the main direction, which will be the main trend of the research on t diagnostic criteria of qi and yin deficiency syndrome.
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Objective To analyze the development trend of global and domestic major disaster medical rescue, pre-dict the development trend of key technologies in major disaster medical rescue, and put forward suggestions for the distribution of resources and technical training model in domestic major disaster medical rescue by investigating and comparing the researches in domestic major disaster medical rescue. Methods Data of disaster medical rescue were analyzed using the scientific knowledge mapping analysis tools ( TDA and VOSVIEWER) with the Web of Science Database-covered titles of papers on disaster medical rescue in 1995-2017 as the study objects. Results A total of 1333 titles of papers on disaster medical rescue were retrieved from the Web of Science Database, from which 89 high frequency co-occurrence key words in 7 major categories were selected. Conclusion The research on crush syndrome, posttraumatic stress syndrome, fracture, spinal cord injury, rehabilitation, casualty classification, and field hospital is advantageous over that on telemedicine, communication, pediatrics, personal identification and education in domestic major disaster medical rescue. Disaster rescue system should be established, research on disaster rescue concept, techniques and equipments should be deepened, and training model of emergency medical rescue should be expanded in our country.
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The external and internal characteristics of domestic master and doctorial papers on rheumatoid arthritis were analyzed by visualization analysis, which revealed the publication of and hotspots and frontiers in domestic master and doctorial papers on rheumatoid arthritis, and can thus provide reference for the development of medical information resources and recent advances in rheumatoid arthritis for the broad masses of scientific workers.
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Objective To study the hot spots and frontiers in studies on domestic hospital libraries by visualization analysis.Methods A total of 2820 CNKI-covered papers on hospital libraries from 2005 to 2015 were analyzed u-sing CiteSpace 3.8.Results The clustering map of key words in papers on hospital libraries was plotted, the fre-quency of key words and centrality were listed, and the burst terms were mapped.Conclusion The hot spots in studies on hospital libraries are readers service, network and resources development.Subject service and digital li-brary are the frontiers.Review of hospital class plays an important role in promoting the construction of hospital li-braries.Service of hospital libraries is focused on the construction of key subjects in hospitals.
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By using the software CiteSpace Ⅱ,the paper makes a quantitative analysis and interpretation of research literatures on telemedicine in SCIE of Web of Science from three perspectives,namely the research hotspots,knowledge base and research fronts.The research hotspots of telemedicine mainly include tele-diagnosis,tele-monitoring and evaluation of the application effects of telemedicine.It sets forth key literatures representing the knowledge base one by one and reveals that most of them focus on clinical applications.The analysis of burst terms indicates that more attention has been paid to tele-monitoring and distance education of chronic diseases in recent years and mobile technology is one of the greatest driving forces for the development of telemedicine at the present stage.
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Tai Chi Chuanis a traditional Chinese method of regimen and health care, which has attracted wide attention from countries in the world. This article was aimed to analyze the current situation and hot spots about Tai Chi Chuan for future research. A total of 1349 articles were retrieved from Web of Science from 1981 to 2013. CiteSpace was used to map knowledge domain of 1349 articles in order to explore the current situation and hot spots aboutTai Chi Chuan internationally. The results showed that the research onTai Chi Chuan showed a rising trend. The main research regions were in the United States and China. The research fields were extended from medicine and sport science to psychology, engineering and computer science. The hot spots were focused on physical control, psychology and cardiovascular diseases. It was concluded thatTai Chi Chuan was a method benefit to both physical and mental health. The focus of future Tai Chi Chuan research was on basic theory, action mechanism and strict evidences.