ABSTRACT
Objective:To observe the effects of repetitive transcranial magnetic stimulation combined with divergent shock wave on muscle spasm in patients with traumatic spinal cord injury,and to explore a new clinical treatment method for the disease. Method:Fifity-nine patients with traumatic spinal cord injury with muscle spasm from January 2017 to June 2021 were selected and randomly divided into the observation group(n=30)and the control group(n=29)with the method of random number table.The patients in the observation group received repeated transcranial magnet-ic stimulation combined with divergent shock wave therapy,while the patients in the control group received ba-clofen treatment.Both groups received conventional rehabilitation therapy,including exercise therapy,acupunc-ture and massage.The treatment time was 8 weeks.The modified Ashworth score,Barthel index and SF-36 score of the patients in the observation group and the control group were compared before and after treatment. Result:After treatment,the effective rate of the observation group was 86.67％,which was significantly high-er than that of the control group(P＜0.05).The total score of Barthel index and SF-36 score of the two groups were significantly increased compared with those before treatment(P＜0.05).The Barthel index and SF-36 score in the observation group were significantly higher than those in the control group(P＜0.05). Conclusion:Repetitive transcranial magnetic stimulation combined with divergent shock wave can effectively im-prove the symptoms of muscle spasm in patients with traumatic spinal cord injury and can fully improve their ability of daily life and quality of life,which has achieved good clinical efficacy.
ABSTRACT
Introduction: Tetanus is a highly fatal infection that causes tonic convulsions. Although magnesium sulfate may be effective as a treatment option for myopathic symptoms, there is little knowledge regarding its use. Therefore, this study assessed the use of magnesium sulfate for patients with tetanus requiring critical care management.Methods: Using multiple mailing lists of registered physicians in Japan, a questionnaire survey was conducted on the conditions during which magnesium sulfate was used for patients with tetanus requiring critical care management. An internet questionnaire form service was utilized.Results: The number of targets in this study was 24,266 and responses were received from 604 physicians, 252 of whom treated patients with tetanus requiring critical care management. In total, 126 of the above physicians used magnesium sulfate for tetanus.Conclusion: Magnesium sulfate was used for a substantial number of patients with tetanus requiring critical care management. To establish the utility of magnesium sulfate as a tetanus treatment option, further evidence is required.
ABSTRACT
El síndrome de la persona rígida es un trastorno neurológico infrecuente y desconcertante, caracterizado por contractura progresiva, rigidez y espasmos dolorosos que afectan la musculatura axial, lo que imposibilita la deambulación del paciente. Se presenta un paciente masculino de 22 años de edad con manifestaciones clínicas y electromiográficas compatibles con esta entidad nosológica. El tratamiento descrito para la enfermedad no produjo mejoría de los síntomas. Con respecto a los casos descritos en la literatura científica, es el primer paciente con diagnóstico de síndrome de la persona rígida que ha recibido una dosis de diazepam de 500 mg diarios por vía oral sin efectos adversos y una dosis en bolo de propofol de 800 mg para lograr la relajación muscular(AU)
Stiff-Man Syndrome is an uncommon and disturbing neurological disorder characterized by progressive contracture, stiffness and painful spasms that affect the axial musculature, making it impossible for the patient to walk around. We present a 22-year-old male patient with clinical and electromyographic manifestations compatible with this nosological disease. The treatment described for the disease did not produce an improvement in symptoms. Regarding the cases described in the scientific literature, this is the first patient diagnosed with Stiff-Man Syndrome who has received a dose of diazepam of 500 mg daily orally without adverse effects and a bolus dose of 800 mg of propofol to achieve muscle relaxation(AU)