Periodontal therapy for hopeless mandibular anterior teeth: a retrospective case report with a multidisciplinary approach and a 20-year follow-up

Introduction: This case report presents the intentional periodontal maintenance of two periodontal hopeless lower central incisors with a multidisciplinary approach and 20-year follow-up. Case presentation: A 36-year-old male, in 2001, was diagnosed with aggressive periodontitis, gingival swelling, bleeding, and mandibular central incisors with mobility and poor prognosis. Following periodontal therapy (phase I), root canal treatment, and occlusal adjustment, #31 and #41 were gently extracted to remove the granulation tissues, calculus, and infected cementum from the root surface. Then, tetracycline-HCl was applied for 5 minutes on the root surfaces. The teeth were repositioned into the sockets and splinted with a lingual bar. At 3 months, the bar was removed, and a free gingival autogenous graft was done to improve the local keratinized tissue width. Mobility scores, pocket depths, and clinical attachment levels were recorded, and radiographs were taken at 1, 5, and 20 years. The 5-year follow-up showed that the teeth were clinically and radiographically in function. There was a reduction in probing depth and a gain in clinical attachment and radiographic alveolar bone levels. After 20 years, #41 was stable, but #31 had external root resorption, leading to a new treatment plan (dental implants) and extraction. Conclusion: The clinical result of this case was satisfactory for 20 years. Intentional periodontal maintenance of the teeth may be an alternative treatment, even considering the high level of complexity.

Robot-assisted, laparoscopic and open radical cystectomy for bladder cancer: A systematic review and network meta-analysis

ABSTRACT Objectives: To evaluate the safety and effectiveness of robot-assisted radical cystectomy (RARC), laparoscopic radical cystectomy (LRC), and open radical cystectomy (ORC) in bladder cancer. Methods: A literature search for network meta-analysis was conducted using international databases up to February 29, 2024. Outcomes of interest included baseline characteristics, perioperative outcomes and oncological outcomes. Results: Forty articles were finally selected for inclusion in the network meta-analysis. Both LRC and RARC were associated with longer operative time, smaller amount of estimated blood loss, lower transfusion rate, shorter time to regular diet, fewer incidences of complications, and fewer positive surgical margin compared to ORC. LRC had a shorter time to flatus than ORC, while no difference between RARC and ORC was observed. Considering lymph node yield, there were no differences among LRC, RARC and ORC. In addition, there were statistically significant lower transfusion rates (OR=-0.15, 95% CI=-0.47 to 0.17), fewer overall complication rates (OR=-0.39, 95% CI=-0.79 to 0.00), fewer minor complication rates (OR=-0.23, 95% CI=-0.48 to 0.02), fewer major complication rates (OR=-0.23, 95% CI=-0.68 to 0.21), fewer positive surgical margin rates (OR=0.22, 95% CI=-0.27 to 0.68) in RARC group compared with LRC group. Conclusion: LRC and RARC could be considered as a feasible and safe alternative to ORC for bladder cancer. Notably, compared with LRC, RARC may benefit from significantly lower transfusion rates, fewer complications and lower positive surgical margin rates. These data thus showed that RARC might improve the management of patients with muscle invasive or high-risk non-muscle invasive bladder cancer.

Retrograde intrarenal surgery with or without ureteral access sheath: a systematic review and meta-analysis of randomized controlled trials

ABSTRACT Introduction: The ureteral access sheath (UAS) is a medical device that enables repeated entrance into the ureter and collecting system during retrograde intrarenal surgery (RIRS). Its impact on stone-free rates, ureteral injuries, operative time, and postoperative complications remains controversial. Therefore, we performed a systematic review and meta-analysis comparing RIRS with versus without UAS for urolithiasis management. Purpose: To compare outcomes from retrograde intrarenal surgery (RIRS) for stone extraction with or without ureteral access sheath (UAS); evaluating stone-free rate (SFR), ureteral injuries, operative time, and postoperative complications. Materials and Methods: We systematically searched PubMed, Embase, and Cochrane Library in June 2024 for randomized controlled trials (RCTs) evaluating the efficacy and safety outcomes of UAS use in RIRS for urolithiasis treatment. Articles published between 2014 and 2024 were included. Pooled risk ratios (RRs) and mean differences (MDs) were calculated for binary and continuous outcomes, respectively. Results: Five RCTs comprising 466 procedures were included. Of these, 246 (52.7%) utilized UAS. The follow-up ranged from 1 week to 1 month. UAS reduced the incidence of postoperative fever (RR 0.49; 95% confidence interval [CI] 0.29-0.84; p=0.009), and postoperative infection (RR 0.50; 95% CI 0.30-0.83; p=0.008). There were no significant differences between groups in terms of SFR (RR 1.05; 95% CI 0.99-1.11; p=0.10), ureteral injuries (RR 1.29; 95% CI 0.95-1.75; p=0.11), operative time (MD 3.56 minutes; 95% CI −4.15 to 11.27 minutes; p=0.36), or length of stay (MD 0.32 days; 95% CI −0.42 to 1.07 days; p=0.40). Conclusion: UAS leads to a lower rate of post-operative fever and infection. However, UAS did not significantly reduce or increase the SFR or the rate of ureteral injuries during RIRS for patients with urolithiasis. The use of UAS should be considered to decrease the risk of infectious complications, particularly in those who may be at higher risk for such complications.

First impressions of Telesurgery robotic-assisted radical prostatectomy using the Edge medical robotic platform

ABSTRACT Purpose: We reported, as a referral center in prostate cancer, our perspectives and experience performing Telesurgery using robotic surgery and 5G network. Material and methods: We described and illustrated the Telesurgery applications and outcomes to treat a patient with prostate cancer located 1300 kilometers away from the surgeon (Beijing-Harbin) in China. We used the Edge Medical Robot (MP1000) in November 2023 in a 71-year-old patient with Gleason 6 (ISUP 1) in 8 cores from 13, PSA of 14 ng/dL, and clinical stage cT2a. MRI described a PIRADS 5 nodule on the left peripheral zone at the base, and 20gr prostate. We described details about the connection between centers, perioperative outcomes, and our perspectives as a referral center in prostate cancer. Results: We had no delays, or problems with network connection between the centers. The procedure was performed in 60 minutes, with no intra- or postoperative complications. Estimated blood loss was 100 mL. The patient was ambulating soon after anesthesia recovery. Final pathology described a Gleason 6 (ISUP 1) involving the left base and left seminal vesicle, negative surgical margins, and no lymph node involvement (pT3bN0). The patient was continent soon after catheter removal (7 days). Conclusion: As technological progress introduced novel robotic platforms and high-speed networks, the concept of Telesurgery became a tangible reality while 5G technology solved latency and transmission concerns. However, with these advancements, ethical considerations and regulatory frameworks should underline the importance of transparency and patient safety with responsible innovation in the field.

Robot-assisted radical nephroureterectomy using the KangDuo Surgical Robot-01 System versus the da Vinci System: a multicenter prospective randomized controlled trial

ABSTRACT Introduction: We aim to compare the safety and effectiveness of the KangDuo (KD)-Surgical Robot-01 (KD-SR-01) system and the da Vinci (DV) system for robot-assisted radical nephroureterectomy (RARNU). Materials and Methods: This multicenter prospective randomized controlled trial was conducted between March 2022 and September 2023. Group 1 included 29 patients undergoing KD-RARNU. Group 2 included 29 patients undergoing DV-RARNU. Patient demographic and clinical characteristics, perioperative data, and follow-up outcomes were collected prospectively and compared between the two groups. Results: There were no significant differences in patient baseline demographic and preoperative characteristics between the two groups. The success rates in both groups were 100% without conversion to open or laparoscopic surgery or positive surgical margins. No significant difference was observed in docking time [242 (120-951) s vs 253 (62-498) s, P = 0.780], console time [137 (55-290) min vs 105 (62-220) min, P = 0.114], operative time [207 (121-460) min vs 185 (96-305) min, P = 0.091], EBL [50 (10-600) mL vs 50 (10-700) mL, P = 0.507], National Aeronautics and Space Administration Task Load Index scores, and postoperative serum creatinine levels between the two groups. None of the patients showed evidence of distant metastasis, local recurrence, or equipment-related adverse events during the four-week follow-up. One (3.4%) patient in Group 2 experienced postoperative enterovaginal and enterovesical fistulas (Clavien-Dindo grade III). Conclusions: The KD-SR-01 system is safe and effective for RARNU compared to the DV Si or Xi system. Further randomized controlled studies with larger sample sizes and longer durations are required.

Abdominal complications of ascariasis in childhood

Abstract Objective Complications of ascariasis are a significant cause of abdominal pain in pediatric emergencies, especially where it is endemic. A literature review was conducted with the aim of improving diagnostic and therapeutic approaches for these patients. Data sources A PubMed search was conducted using the key terms "ascariasis complications" and "hepatobiliary ascariasis". The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational studies, case reports, and reviews published up to December 2023. Summary of findings Obstruction of the small bowel is the most common complication. Others that are, rarer and more difficult to properly identify and treat, such as biliary, hepatic, and pancreatic complications, acute appendicitis, Meckel's diverticulitis, or peritoneal granulomas. Hepatic and pancreatic complications are rarer and more serious in children than in adults. While plain radiography is usually the only option in cases of intestinal obstruction, ultrasonography is the examination of choice in cases of hepatobiliary, pancreatic, and appendicular ascariasis complications in childhood. The treatment is clinical and conservative in most patients. Surgical treatment is indicated if conservative therapy fails, or if there are signs of complications. Laparoscopy has been used as an excellent technical alternative in adults with hepatobiliary complications of ascariasis, but further studies on its use in children are still needed. Conclusion The creation of protocols and greater debate on this subject should be encouraged for a better understanding of the disease and to establish an early diagnosis and adequate treatment for children with complications resulting from massive infestation by Ascaris lumbricoides.

Fontes de energia externa no contorno corporal / External energy sources in body contouring

Durante a 39a Jornada Sulbrasileira de Cirurgia Plástica, em abril de 2024, um debate acalorado surgiu em torno da divulgação do uso de tecnologias para cirurgia de contorno corporal nas redes sociais. Um importante questionamento foi feito: elas estão sendo divulgadas prematuramente nas redes sociais antes de serem rigorosamente avaliadas? A frase do Dr. Ian Malcolm, célebre criação de Michael Chrichton, "Vou te dizer o problema com o poder que você está usando aqui, ele não exigiu nenhuma disciplina para obtê-lo" se aplica perfeitamente a essa situação. A divulgação de técnicas em redes sociais deveria exigir a mesma disciplina rigorosa que a pesquisa científica. A ausência de protocolos de pesquisa aprovados pelo Conselho Nacional de Ética em Pesquisa e de publicações de alto nível de evidência em revistas revisadas por pares levanta preocupações. O poder de aprimorar nossos resultados com o uso dessas fontes de energia externa é real e seu uso consiste em um grande avanço dentro da cirurgia plástica. No entanto, é imperativo que os cirurgiões plásticos exerçam cautela ao promover novas tecnologias. A disciplina científica deve ser o alicerce de qualquer avanço, e a divulgação responsável deve preceder a popularização. Somente assim, poderemos garantir que os pacientes se beneficiem de tratamentos seguros e eficazes, sem comprometer a integridade da nossa especialidade.

During the 39th South Brazilian Plastic Surgery Conference, in April 2024, a heated debate arose regarding the promotion of the use of technologies for body contouring surgery on social media. An important question was raised: are they being prematurely promoted on social media before being rigorously evaluated? The quote from Dr. Ian Malcolm, a famous creation of Michael Chrichton, "I'll tell you the problem with the power you're using here, it didn't require any discipline to attain it" applies perfectly to this situation. Promoting techniques on social media should require the same rigorous discipline as scientific research. The absence of research protocols approved by the National Research Ethics Council and high-level evidence publications in peer- reviewed journals raises concerns. The power to enhance our results using these external energy sources is real, and its use represents a significant advancement within plastic surgery. However, it is imperative that plastic surgeons exercise caution when promoting new technologies. Scientific discipline should be the foundation of any advancement, and responsible disclosure should precede popularization. Only then can we ensure that patients benefit from safe and effective treatments without compromising the integrity of our specialty.

Cystocele management in multisurgical patients: a comprehensive case report emphasizing advanced diagnostic and surgical precision

Pelvic organ prolapses (POP), particularly cystocele, presents significant challenges in postmenopausal women, exacerbated in those with multiple caesarean sections (LSCS) and comorbidities like diabetes mellitus. This case report details the successful management of a 62-year-old woman with a large cystocele, three LSCS, and diabetes mellitus. Thorough preoperative evaluation, including ultrasound and diagnostic laparoscopy, guided surgical planning. Anterior colporrhaphy restored support to the anterior vaginal wall. Perioperative care included strict glycemic control and antibiotic prophylaxis. Multidisciplinary collaboration ensured comprehensive management. This case highlights the importance of advanced diagnostics, meticulous surgical planning, and multidisciplinary care in complex cystocele cases.

Pregnancy over caesarean scar site-account of four unusual cases in the form of a case series

Caesarean scar ectopic pregnancy (CSEP) is an ectopic pregnancy located in the lower uterine segment. Although it is one of the rarest types of ectopic pregnancy, the worldwide increasing rate of caesarean sections has made it important for young gynaecologists to be aware of the challenges posed by CSEP and its successful management. Doppler ultrasounds play a major role in its diagnosis. Early diagnosis is the key to a good outcome as untimely delay can lead to life-threatening haemorrhage, uterine rupture and irreversible loss of fertility. We present a case series of 4 patients of caesarean scar site ectopic pregnancy who presented to the gynaecology emergency and were treated successfully with various modalities depending on their patient profile.

Bacteriology and antibiotic sensitivity in gynaecological abdominal surgical site infections

Background: Surgical site infection increases the rate of re hospitalisation, the use of health care, diagnostic, and therapeutic resources, and hospital costs. Severe sequelae may exacerbate primary and devastating infections. About 39-51% of pathogens causing surgical site infections were documented to be resistant to standard prophylactic antibiotics. This study aimed to calculate surgical site infection rate at our hospital. To identify the isolates causing surgical site infections and study anti-microbial susceptibility pattern of isolated organisms.Methods: This observational study was done among patients who underwent abdominal gynaecological surgeries and who developed surgical site infection in department of obstetrics and gynaecology in Maharajahs institute of medical sciences during May 2022 to April 2024.Results: Surgical site infection rate at our hospital is 18.29%, there are 30 surgical site infections, 76.7% cases are culture positive, 23.3% cases are sterile, 52.2% cases are gram negative, 47.8% are gram positive. Most common organism isolated is E. coli (39%) followed by Staphylococcus aureus (26%), enterococcus (21.7%), Pseudomonas (8.6%), Klebsiella (4.3%). Antibiotic susceptibility pattern shows maximum overall sensitivity of organisms to amikacin (65.4%) followed by gentamicin (56%), piperacillin tazobactum (52.17%), amoxyclav (47.8%) followed by rest of drugs.Conclusions: Practice of routine culture and sensitivity of surgical site infections can prevent grave complications, limit cost of treatment, prevent fast emerging antimicrobial resistance. In our study, complications are limited to need for secondary suturing. The most susceptible drug in our study is amikacin, thus, it can be incorporated as a part of empirical treatment in patients with surgical site infection before the culture sensitivity report is obtained.

A study of different routes of hysterectomies and its outcome in benign gynaecological conditions in tertiary care centre in Tamil Nadu

Background: Hysterectomy is the most frequently performed major surgical procedure in gynaecology. It is an efficacious treatment option for numerous gynaecological conditions. This study aimed to investigate the different routes of hysterectomies, such as abdominal, vaginal, and laparoscopic, and their outcomes in benign gynaecological diseases in a tertiary care centre in Tamil Nadu.Methods: This retrospective observational study included 200 patients who were admitted to the department of obstetrics and gynaecology at Chettinad Hospital and Research Institute, Tamil Nadu, India underwent hysterectomy between January 2021 and January 2023, and were collected from the MRD. Patient history included age, parity, indication for surgery, duration of surgery, route of hysterectomy, intraoperative or postoperative complications, duration of hospital stay were collected.Results: This study analysed 200 patients who underwent hysterectomy, with the majority aged between 40-50 years (60%) and multiparous women (85%). The most common indications were abnormal uterine bleeding (80%), uterine prolapse (12%), benign ovarian cyst (5%) and post-menopausal bleeding (3%). Total abdominal hysterectomy (49%) was the most common approach, followed by vaginal/non-descent hysterectomy (19.5%), total laparoscopic hysterectomy (16.5%), and laparoscopic-assisted vaginal hysterectomy (15%). Complications included wound infections (3.5%), excessive bleeding (3%), bladder injuries (1%) and ureter injury (0.5%). The procedure duration and hospital stay were shorter for vaginal and laparoscopic approaches than for open abdominal hysterectomy. The laparoscopic approach had the lowest rates of complications such as bladder injuries and excessive bleeding.Conclusions: Vaginal hysterectomy is preferred for uterine prolapse, whereas laparoscopic techniques offer benefits such as reduced blood loss and lesser hospital stay and morbidities. Although rare, complications emphasize the need for careful postoperative monitoring to optimize patient care.

Mais Complicações em Mulheres após Revascularização do Miocárdio Mesmo com Tempos Cirúrgicos Reduzidos: Atenção por Equidade e Melhoria da Qualidade / More Hospital Complications in Women after Cabg Even for Reduced Surgical Times: Call to Action for Equity in Quality Improvement

Resumo Fundamento Análises em grandes registros apontam desfechos desfavoráveis para mulheres submetidas à cirurgia de revascularização do miocárdio (CRM), enquanto estudos randomizados sofrem com a falta de representatividade. Objetivo Comparar os resultados hospitalares ajustados entre homens e mulheres submetidos à CRM. Métodos Entre julho de 2017 e junho de 2019, 3991 pacientes foram submetidos à CRM primária isolada, tanto de forma eletiva como de urgência, em 5 hospitais de estado de São Paulo, Brasil. Para equilibrar as diferenças entre homens e mulheres, as populações foram ajustadas utilizando o Propensity Score Matching. Os desfechos considerados para análise foram os utilizados pelo STS Adult Database. As análises foram conduzidas no software R, considerando significância valores de p < 0,05. Resultados Após o Propensity Score Matching (1:1), cada grupo incluiu 1089 pacientes. Em relação às variáveis intraoperatórias os homens apresentaram maior tempo de CEC (p<0,001), tempo cirúrgico (p<0,001), número de anastomoses distais (p<0,001) e uso de enxertos arteriais. Em relação aos desfechos as mulheres apresentaram maior incidência de infecção de ferida profunda (p=0,006), tempo prolongado na Unidade de Terapia Intensiva (p=0,002), maior necessidade do uso de balão intraórtico (p=0,04), maior taxa de transfusão sanguínea (p<0,001), maior readmissão hospitalar em até 30 dias após a cirurgia (p=0,002) e maior taxa de óbitos (p=0,03). Conclusões Apesar dos homens terem apresentado um maior tempo de CEC, maior número de enxertos arteriais e maior número de anastomoses distais, os resultados imediatos após CRM foram piores em mulheres.

Abstract Background Analyses of extensive registries indicate adverse outcomes for women undergoing coronary artery bypass grafting (CABG) surgery, while randomized studies often lack representativeness. Objective To compare adjusted hospital outcomes between men and women undergoing CABG. Methods From July 2017 to June 2019, 3991 patients underwent primary isolated CABG, both electively and urgently, in 5 hospitals in the state of São Paulo, Brazil. To mitigate demographic differences between men and women, populations were adjusted using propensity score matching (PSM). The outcomes considered for analysis were those used by the STS Adult Database. The analyses were performed using R software, with a significance set at p<0.05. Results After PSM (1:1), each group included 1089 patients. Regarding intraoperative variables, men exhibited longer cardiopulmonary bypass (CPB) time (p<0.001), surgical time (p<0.001), a higher number of distal anastomoses (p<0.001), and increased use of arterial grafts. Regarding outcomes, women had a higher incidence of deep sternal wound infection (p=0.006), prolonged Intensive Care Unit stay (p=0.002), increased need for an intra-aortic balloon pump (p=0.04), higher blood transfusion rates (p<0.001), higher 30-day hospital readmission rates after surgery (p=0.002) and higher mortality rate (p=0.03). Conclusions Although men had longer CPB times, a greater number of arterial grafts, and a greater number of distal anastomoses, immediate results after CABG were poorer in women.

A Comprehensive Review of the Current State of Robot-assisted Laparoscopic Salvage Prostatectomy

ABSTRACT Background and Objective Salvage robot assisted radical prostatectomy (sRARP) is performed for patients with biochemical or biopsy proven, localized prostate cancer recurrences after radiation or ablative therapies. Traditionally, sRARP has been avoided by lower volume surgeons due to technical demand and high complication rates. Post-radiation sRARP outcomes studies exist but remain few in number. With increasing use of whole gland and focal ablative therapies, updates on sRARP in this setting are needed. The aim of this narrative review is to provide an overview of recently reviewed studies on the oncologic outcomes, functional outcomes, and complications after post-radiation and post-ablative sRARP. Tips and tricks are provided to guide surgeons who may perform sRARP. Materials and Methods We performed a non-systematic literature search of PubMed and MEDLINE for the most relevant articles pertaining to the outlined topics from 2010-2022 without limitation on study design. Only case reports, editorial comments, letters, and manuscripts in non-English languages were excluded. Key Content and Findings Salvage robotic radical prostatectomy is performed in cases of biochemical recurrence after radiation or ablative therapies. Oncologic outcomes after sRARP are worse compared to primary surgery (pRARP) though improvements have been made with the robotic approach when compared to open salvage prostatectomy. Higher pre-sRARP PSA levels and more advanced pathologic stage portend worse oncologic outcomes. Patients meeting low-risk, EAU-biochemical recurrence criteria have improved oncologic outcomes compared to those with high-risk BCR. While complication rates in sRARP are higher compared to pRARP, Retzius sparing approaches may reduce complication rates, particularly rectal injuries. In comparison to the traditional open approach, sRARP is associated with a lower rate of bladder neck contracture. In terms of functional outcomes, potency rates after sRARP are poor and continence rates are low, though Retzius sparing approaches demonstrate acceptable recovery of urinary continence by 1 year, post-operatively. Conclusions Advances in the robotic platform and improvement in robotic experience have resulted in acceptable complication rates after sRARP. However, oncologic and functional outcomes after sRARP in both the post-radiation and post-ablation settings are worse compared to pRARP. Thus, when engaging in shared decision making with patients regarding the initial management of localized prostate cancer, patients should be educated regarding oncologic and functional outcomes and complications in the case of biochemically recurrent prostate cancer that may require sRARP.

Mesentery-Sparing Technique: a New Intracorporeal Approach for Urinary Diversion in Robot-Assisted Radical Cystectomy

ABSTRACT Background Robotic-assisted radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD) is associated with significant morbidity and mortality. We present an alternative technique that preserves the complete mesenteric vascularization during the isolation of the intestinal segment used in ICUD, including distal vessels. This approach aims to minimize the risk of ischemia in both the ileal anastomosis and the isolated loop at the diversion site. Methods This cohort study included 31 patients, both male and female, who underwent RARC with ICUD from February 2018 to November 2023, performed by a single surgeon. Intraoperative and postoperative complications data were retrieved for analysis, employing our proposed mesentery-sparing technique in all cases. The primary endpoint was the incidence of intraoperative and postoperative complications directly attributable to the mesentery-sparing approach in ICUD. Secondary endpoints included other postoperative variables not directly related to mesentery preservation, such as the incidence of postoperative ileus requiring parenteral nutrition and the duration of hospitalization. Results None of the patients experienced intraoperative or postoperative complications directly related to mesentery-sparing, such as intestinal fistulae or internal hernias. The median duration of hospitalization was 6 days, and postoperative ileus necessitating total parenteral nutrition occurred in 19% of the patients. Minor complications (Clavien-Dindo grades I-II) accounted for 27.6% of the cases and major complications (grades III-V) accounted for 20.6%. Conclusion The mesentery-sparing technique outlined herein offers an alternative method for preserving the vascularization of intestinal segments and reducing the risk of intestinal complications in ICUD during RARC.

The 2012 Briganti nomogram not only predicts lymph node involvement but also disease progression in surgically treated intermediate-risk prostate cancer patients with PSA <10 ng/mL, ISUP grade group 3, and clinical stage up to cT2b

ABSTRACT Purpose We assessed the prognostic impact of the 2012 Briganti nomogram on prostate cancer (PCa) progression in intermediate-risk (IR) patients presenting with PSA <10ng/mL, ISUP grade group 3, and clinical stage up to cT2b treated with robot assisted radical prostatectomy eventually associated with extended pelvic lymph node dissection. Materials and Methods From January 2013 to December 2021, data of surgically treated IR PCa patients were retrospectively evaluated. Only patients presenting with the above-mentioned features were considered. The 2012 Briganti nomogram was assessed either as a continuous and a categorical variable (up to the median, which was detected as 6%, vs. above the median). The association with PCa progression, defined as biochemical recurrence, and/or metastatic progression, was evaluated by Cox proportional hazard regression models. Results Overall, 147 patients were included. Compared to subjects with a nomogram score up to 6%, those presenting with a score above 6% were more likely to be younger, had larger/palpable tumors, presented with higher PSA, underwent tumor upgrading, harbored non-organ confined disease, and had positive surgical margins at final pathology. PCa progression, which occurred in 32 (21.7%) cases, was independently predicted by the 2012 Briganti nomogram both considered as a continuous (Hazard Ratio [HR]:1.04, 95% Confidence Interval [CI]:1.01-1.08;p=0.021), and a categorical variable (HR:2.32; 95%CI:1.11-4.87;p=0.026), even after adjustment for tumor upgrading. Conclusions In IR PCa patients with PSA <10ng/mL, ISUP grade group 3, and clinical stage up to cT2b, the 2012 Briganti nomogram independently predicts PCa progression. In this challenging subset of patients, this tool can identify prognostic subgroups, independently by upgrading issues.

Alargamiento estético de corona con planeación digital mediante el uso de guía quirúrgica / Esthetic crown lengthening with digital planning using a surgical guide

Introducción: el alargamiento de corona relacionado con la estética tiene como objetivo revelar una longitud adecuada de la corona y disminuir la exposición gingival. El procedimiento incluye gingivectomía y alveolectomía para restablecer el tejido gingival supracrestal requerido protésicamente según la dimensión fisiológica. Mediante un escaneo intraoral del maxilar, mandíbula y posición intercuspídea máxima y utilizando un software especializado, se diseña de manera digital la forma de los dientes y el contorno gingival. Este diseño genera una imagen de la restauración estética deseada para el prostodoncista y periodoncista. La fabricación física del diseño es asistida por computadora (CAD-CAM), creando una guía quirúrgica de resina acrílica moldeada al vacío para determinar la longitud de la corona clínica requerida en la cirugía. Objetivo: el caso interdisciplinario presentado describe una técnica innovadora empleando el flujo digital mediante un software que, a partir de un escaneo oral, diseña de manera digital un Mock-Up utilizado como guía para la cirugía periodontal. Presentación del caso: acude a clínica de la Maestría en Periodoncia de la Universidad Autónoma de Coahuila (UAdeC) paciente de 52 años, ASA I, para una cirugía periodontal con fines estéticos. Se procedió a la cirugía, colocando el Mock-Up en la región anterosuperior como guía para la gingivectomía. Luego, se realizó el levantamiento de colgajo antes de la alveolectomía, tomando en cuenta la longitud del tejido gingival supracrestal. Por último, se suturaron los tejidos blandos con técnica de colchonero horizontal. Resultados: siete días después, se retiran los puntos apreciando una cicatrización correcta y uniforme de los tejidos. Conclusiones: este abordaje digital ofrece una reducción significativa del tiempo quirúrgico, además de una estética satisfactoria y una precisa arquitectura gingival (AU)

Introduction: crown lengthening for aesthetic purposes aims to reveal an adequate crown length and reduce gingival exposure. The procedure includes gingivectomy and alveolectomy to restore the prosthetically required supracrestal gingival tissue according to physiological dimensions. Through an intraoral scan of the maxilla, mandible, and maximum intercuspidal position, and using specialized software, the shape of the teeth and the gingival contour are digitally designed. This design generates an image of the desired aesthetic restoration for the prosthodontist and periodontist. The physical fabrication of the design is computer-assisted (CAD-CAM), creating a vacuum-formed acrylic resin surgical guide to determine the clinical crown length required in surgery. Objective: the presented interdisciplinary case describes an innovative technique using digital workflow through software that, from an oral scan, digitally designs a Mock-Up used as a guide for periodontal surgery. Case presentation: a 52-year-old ASA I patient attended the Periodontics Master's clinic at Universidad Autónoma de Coahuila (UAdeC) for periodontal surgery with aesthetic purposes. The surgery was performed by placing the Mock-Up in the anterosuperior region as a guide for gingivectomy. Then, a flap was raised before the alveolectomy, considering the length of the supracrestal gingival tissue. Finally, the soft tissues were sutured with a horizontal mattress suture technique. Results: seven days later, the sutures were removed, showing correct and uniform tissue healing. Conclusions: this digital approach offers a significant reduction in surgical time, in addition to satisfactory esthetics and precise gingival architecture (AU)

Carcinoma oral de células escamosas en reborde alveolar / Squamous cell carcinoma in the alveolar ridge

El carcinoma oral de células escamosas o epidermoide o espinocelular, es la neoplasia maligna más común en cavidad oral y orofaringe, representa de 3-5% de todas las neoplasias y da metástasis a los ganglios linfáticos regionales. Los factores de riesgos son múltiples, el consumo excesivo de alcohol y tabaco son los más reconocidos, los movimientos parafuncionales, la higiene y nutrición y por supuesto la genética, todos son factores importantes en el desarrollo de este carcinoma. Tiene una prevalencia mayor en el sexo masculino, aunque en los últimos años se ha visto un aumento en el sexo femenino posiblemente por el aumento en el consumo de alcohol y tabaco. La edad comprende entre la cuarta a sexta década de la vida, por el aumento en el consumo de alcohol y tabaco en este rango de edad. Las localizaciones más comunes son el borde lateral de la lengua y el piso de la boca. La presentación clínica es variable, puede encontrarse en un principio como una placa blanca o roja asintomática, exofítico, ulcerada, granular y bordes indurados. El tratamiento debe ser quirúrgico radical con radio o quimioterapia y el pronóstico depende del tiempo del diagnóstico (AU)

Squamous cell carcinoma, also known as epidermoid or squamous cell carcinoma, is the most common malignant neoplasm in the oral cavity and oropharynx. It represents 3 to 5% of all neoplasms and metastasizes to regional lymph nodes. There are multiple risk factors, with excessive alcohol and tobacco consumption being the most recognized. Parafunctional movements, hygiene and nutrition, and of course genetics, are all important factors in the development of this carcinoma. It has a higher prevalence in males, although in recent years there has been an increase in females, possibly due to increased alcohol and tobacco consumption. The age range typically affected is the 4th to 6th decade of life, due to the increased alcohol and tobacco consumption within this age range. The most common locations are the lateral border of the tongue and the floor of the mouth. The clinical presentation varies and can initially appear as an asymptomatic white or red plaque, exophytic, ulcerated, granular, or with indurated borders. The treatment should involve radical surgery with radiotherapy or chemotherapy, and the prognosis depends on the timing of diagnosis (AU)

Experience in the treatment of liver echinococcosis in Grodno Region, Belarus

Background: A parasitic hydatid disease called liver echinococcosis is brought on by the tapeworm echinococcus and is a reason for concern for global health. In addition to the liver, the lungs can harbor parasites. In the life cycle of parasites, humans occupy a middle position. Depending on the size and intensity of the cyst, the clinical signs can vary and be non-specific. The complications include bleeding, perforation, suppuration, cyst rupture, mechanical jaundice, and portal hypertension. Here is an analysis of own results of surgical treatment of patients with liver echinococcosis in Grodno region, Belarus between June 2012 to October 2022. Methods: The research design was cross-sectional. Diagnostic methods that are instrumental and laboratory-based include a general blood test, a biochemical blood test, an enzyme immunoassay (IFA), abdominal and retroperitoneal MRIs and ultrasounds, abdominal and chest CT scans and brain scans. There were 10 men and 17 women among the 27 patients. The age range of the majority of the patients was 18 to 83. Results: All patients underwent resections, including laparoscopic procedures. One of the patients in our series of cases received a two-stage therapy regimen due to a secondary focus of echinococcosis in the left lung. In our series of cases, no postoperative complications or mortality occurred. Conclusions: Patients with hepatic echinococcosis should be treated at specialized hospitals. Abdominal, chest, and brain CT scans are required in order to search for additional foci. When it comes to treating echinococcosis, minimal invasive surgical procedures should be preferred.

Post operative wound infection: a descriptive study

Background: Surgical site infections is the third most commonly reported nosocomial infection which has an adverse impact on the hospital as well as the patient. This study was designed to evaluate the frequency, clinical presentation, common risk factors and different organisms involved.Methods: This study was performed at NRI Medical college, Chinnakakani. This is an Observational descriptive study over a period of one year from September 2022 to September 2023. Biodata of the patients together with their clinical features, diagnosis, type of surgery performed and the development of any complications including wound infection was noted and the data analyzed.Results: Out of 1509 patients in the study, 1101 belonged to obstetrics and 408 to gynaecology surgery. The overall incidence of surgical site infection in the study was 7.9%; 86 (7.8%) in obstetrics group and 33 (8%) in gynaecology group developed infection. Age more than 50 years was found to be a risk factor for postoperative wound infection. Obesity is known to be a well-established risk factor for postoperative wound infection. It was noted that surgical site infection was more common in patients that had low haemoglobin levels pre-operatively. The increased susceptibility to infection in diabetics is an established risk factor.Conclusions: Meticulous surgical technique, proper sterilization, judicious use of antibiotics, improvement of ward environments, control of malnutrition and obesity, treatment of infective foci and diseases like diabetes helps control the morbidity of surgical wound infections.