Avaliação da qualidade de vida e perfil epidemiológico de mulheres adultas com acne facial / Evaluation of quality of life and epidemiological profile of adult women with facial acne

Introdução: A acne é uma doença inflamatória crônica da unidade sebácea. Embora acometa principalmente adolescentes, constata-se uma prevalência elevada em adultos, em especial nas mulheres. A acne feminina adulta tem sido associada a má qualidade de vida (QV) e é capaz de impactar tanto a autoestima como os relacionamentos pessoais e profissionais. Métodos: Trata-se de um estudo transversal de natureza quantitativa realizado através da aplicação de questionários para avaliar a QV e o perfil epidemiológico de mulheres adultas com acne facial entre 25 e 50 anos atendidas em um ambulatório clínico da Universidade do Extremo Sul Catarinense (UNESC). Resultados: Um total de 20 mulheres com acne facial participaram da pesquisa. A idade média foi de 32,45 anos, sendo a maioria branca, casada e com ensino superior incompleto. A maioria não realizou tratamento prévio, e o perfil mais encontrado foi de início da acne na adolescência e de sua persistência na idade adulta. Grande parte das mulheres utilizavam maquiagem. Além disso, foram observados baixos escores em cada um dos quatro domínios do questionário Acne-QoL, com resultados estatisticamente significativos correlacionando a idade com os domínios de autopercepção e de papel emocional. Conclusões: Os resultados destacam que a acne facial tem um impacto significativo na QV de mulheres adultas que a possuem. (AU)

Introduction: Acne is a chronic inflammatory disease of the sebaceous unit. Although adolescents are most commonly affected, there is a high prevalence in adults, especially in women. Acne in adult women has been linked to poor quality of life and may affect self-esteem and personal and professional relationships. Methods: This quantitative cross-sectional study consisted of the administration of a questionnaire to assess the quality of life and epidemiological profile of adult women with facial acne aged 25 to 50 years who were treated at an outpatient clinic at University of Southern Santa Catarina (UNESC). Results: In total, 20 women with facial acne participated in this study. Mean age was 32.45 years, and most participants were white, married, and did not complete their higher education studies. Most of them did not undergo a previous treatment, and the most common profile was acne onset in adolescence with persistence in adulthood. Most women reported using makeup. In addition, low scores were found in all four domains of the Acne-Quality of Life questionnaire, with statistically significant results correlating age with the domains of self-perception and emotional role. (AU)

Investigation of Demodex folliculorum frequency in patients with polycystic ovary syndrome

Abstract: Background: Background: Demodex mites are acari that reside in the pilosebaceous unit of the skin and have been associated with skin disorders. Objective: The objective of this study was to investigate the prevalence of Demodex folliculorum (D. folliculorum) mites in polycystic ovary syndrome patients as well as to examine the relationship between Demodex infestation and the presence of acne and oily or dry skin types in polycystic ovary syndrome patients. Methods: 41 polycystic ovary syndrome patients and 47 non-polycystic ovary syndrome control subjects were enrolled in the study. polycystic ovary syndrome was diagnosed according to the revised 2003 ESHRE/ASRM polycystic ovary syndrome Consensus Workshop Group diagnostic criteria. Microscopic examination of D. folliculorum mites was carried out by standardized skin surface biopsy. The result was considered positive when there were more than 5 mites per cm2. Results: D. folliculorum was positive in 53.7% of the polycystic ovary syndrome patients and 31.9% of the non-polycystic ovary syndrome group (p=0.052). Demodex positivity was significantly associated with acne (p=0.003) and oily skin (p=0.005) in the polycystic ovary syndrome patients but not in the controls. Study limitation: Our study is limited by the relatively small number of subjects and the observational nature of the study design. Conclusion: Demodex mites might have a role in acne pathogenesis in patients with polycystic ovary syndrome. Anti-Demodex treatment may increase the response to treatment of acne. Further studies are indicated.

Acne scars in 18-year-old male adolescents: a population-based study of prevalence and associated factors

Abstract: Background: Acne vulgaris is a pilosebaceous follicle disorder affecting over 85% of adolescents to some degree. It frequently causes psychological distress that may persist into adulthood due to scarring. Little information about post-acne scarring epidemiology is available. Objectives: To describe prevalence, distribution patterns and associated factors of acne scarring in young males, drawing on a representative population sample from a southern Brazilian city. Methods: A cross-sectional study was undertaken during presentation for military service, which is compulsory for all 18-year-old males. A questionnaire was applied, covering topics like diet, smoking habits, ethnicity, family structure, socio-economic level, as well as specific questions about active acne and resulting scars. Dermatologists conducted the clinical examination. Results: A total of 2,201 male adolescents were interviewed and examined. The overall prevalence of acne scarring was 22%. The malar region was the most frequently involved, present in 80% of affected individuals, followed by the frontal region (31.5%), back (17%), anterior chest (8.2%) and mentonian region (6.4%). Correlation between the intensity of clinical acne and the presence of scars was found, but no association was observed with educational level, smoking, ethnicity, obesity or socio-economic status. Conclusions: There is a high prevalence of acne scars among this population. This is the first study to ascertain a correlation between acne scarring and factors such as socio-economic status and educational level. The direct relation between acne severity and scarring indicates that prompt and effective treatment is the best way to reduce scarring.

Quality of life, self-esteem and psychosocial factors in adolescents with acne vulgaris

AbstractBackground:Dermatological diseases, among which acne vulgaris, have psychological impact on the affected generating feelings of guilt, shame and social isolation.Objectives:To compare quality of life, self-esteem and other psychosocial variables amongst adolescents with and without acne vulgaris, and between levels of severity.Methods:Cross-sectional observational study in a sample of 355 high school students from the city of João Pessoa. Data collection was performed with questionnaires and clinical-dermatological evaluation. The primary variables were the incidence of AV; quality of life, set by the Children's Dermatology Quality of Life Index and Dermatology Quality of Life Index; and self-esteem, measured by the Rosenberg Self-Esteem Scale. For calculation of statistical tests, we used the SPSS 20.0 software, considering p=0.05.Results:The sample, with an average age of 16, showed 89.3% prevalence of acne vulgaris. The most prevalent psychosocial issue was "afraid that acne will never cease", present in 58% of affected youth. The median score of Quality of Life in Children's Dermatology Index was different amongst students with and without acne vulgaris (p=0.003), as well as the Quality of Life in Dermatology (p=0.038) scores, so that students with acne vulgaris have worse QoL. There was a correlation between the severity of acne vulgaris and worse quality of life. Self-esteem was not significantly associated with the occurrence or severity of acne vulgaris.Conclusions:acne vulgaris assumes significance in view of its high prevalence and the effect on quality of life of adolescents, more severe at the more pronounced stages of disease (p<0.001). The psychosocial impact of acne vulgaris should be valued in the management of patients with this condition.

Características clínicas y epidemiológicas de pacientes que consultan por acné / Clinical and epidemiological characteristics of patients with acne

El acné es una enfermedad multifactorial que afecta a más de 40 millones de personas a nivel mundial. A pesar de ser uno de los motivos más frecuentes de consulta dermatológica, se carece a nivel nacional de estudios epidemiológicos sobre esta afección. El objetivo del estudio fue describir las características clínico-epidemiológicas de los pacientes que consultaron por acné en la Cátedra de Dermatología del Hospital de Clínicas de marzo a julio de 2013. En este estudio observacional, descriptivo de corte transversal se incluyeron en forma consecutiva 130 pacientes con acné, edad media: 20,3 ± 5,5 años, 62,3% de sexo femenino, y >90% era procedente de Asunción o Departamento Central. El 65,3% reportó antecedentes familiares de acné y la edad de inicio fue más temprana en hombres. La ingesta de grasas fue el factor desencadenante más citado por los hombres, mientras que en las mujeres fue el periodo menstrual. El 63,15% de las mujeres que ingería anticonceptivos refirieron mejoría del acné. Un alto porcentaje (60%) de mujeres presentó acné leve a moderado mientras que el acné severo a muy severo fue más frecuente (65%) en los hombres. Los pacientes con acné leve tuvieron en promedio edades mayores (23 ± 7,4 años) que aquellos con acné severo (18 ± 3,7 años). No se encontró asociación entre la presencia de antecedentes familiares, tabaquismo, irregularidades menstruales, fototipo cutáneo, índice de masa corporal y severidad del acné. Estos resultados pueden servir de base para futuras investigaciones y el establecimiento de protocolos diagnósticos y terapéuticos en el país.

Acne is a multifactorial disease affecting over 40 million people worldwide. Despite thefact that is one of the most frequent reasons for dermatologic consultation, the countryhas no epidemiological studies about this affection. The objective of this study was todescribe the clinical and epidemiological characteristics of patients that consulted for acnein the Department of Dermatology of the Clinical Hospital from March to July 2013. This isa cross-sectional descriptive observational study that included consecutively 130 patientswith acne, mean age: 20.3±5.5 years, 62.3% was women and >90% came fromAsunción and Central Department. Family history of acne was reported by 65.3%. Theacne onset was earlier in men than in women. Fat intake was the triggering factormentioned more frequently by men while beginning of menstruation was in women.Improvement of acne was mentioned by 63.15% of women who used oral contraceptives.A high percentage (60%) of women presented mild to moderate acne while severe tovery severe acne was more common in men (65%). The mean age (23±7.4 years) inpatients with mild acne was higher than in those patients with severe acne (18±3.7 years). No association between the presence of family history, smoking, menstrualirregularities, cutaneous phototype, body mass index was observed. These results mayserve as a baseline for future research and the establishment of diagnostic andtherapeutic protocols in the country.

Acné juvénile : une pathologie fréquente chez les adolescents scolarisés d'Afrique Sub-saharienne

OBJECTIF : Décrire les caractéristiques épidémiologiques et cliniques de l'acné chez les adolescents scolarisés de Yaoundé. MÉTHODOLOGIE : Nous avons mené une étude transversale de Janvier à Avril 2013 au sein de 3 établissements d'enseignement secondaire de la ville de Yaoundé, Cameroun. Tout adolescent âgé de 15-19 ans et atteint d'acné était inclus dans l'étude. RÉSULTATS : Des 535 adolescents examinés, 400 (74,8%) étaient atteints d'acné, dont 214 filles (53,5%) avec un risque plus élevé chez les garçons d'être atteints (odds-ratio (OR) 1,8, intervalle de confiance (IC) à 95% : 1,2-2,7 ; p = 0,005). L'âge moyen était de 16,7 ± 1.3 ans. Les participants âgés de 16 ans étaient les plus affectés (31,7%). Le pic d'âge au début de l'acné était de 12 ans chez les filles (22,4%) et 14 ans chez les garçons (30,1%), avec significativement plus de filles affectées tôt (9-13 ans) que de garçons (14-18 ans) (OR 2,8, IC : 1,8-4,3 ; p < 0,0001). Le visage représentait le siège préférentiel (79%), et, comédons (98%) et papules (95%) étaient les types de lésions les plus nombreuses. L'acné rétentionnelle (58,5%) et l'acné polymorphe (37,5%) étaient les formes les plus rencontrées, et le grade 2 était le degré de sévérité le plus observé (41,5%). CONCLUSION : L'acné est une pathologie fréquente en milieu scolaire Camerounais. Bien que les formes sévères soient rares, les lésions semblent prédominer sur les parties exposées du corps, ce qui pourrait avoir un retentissement sur l'état psycho-affectif et la qualité de vie des patients

Dissatisfaction and acne vulgaris in male adolescents and associated factors

BACKGROUND: Acne vulgaris has high prevalence, disturbing quality of life during adolescence. OBJECTIVES: To measure dissastifaction and acne in 18-year-old male individuals and its associated factors. METHODS: A questionnaire was applied by trained interviewers to all boys during selection for the military service. Dissatisfaction and acne was evaluated using a self-administered face scale. Facial, prestrernal and dorsal acne were evaluated separately. RESULTS: A total of 2,200 adolescents, aged 18 years, were interviewed. Among these, 1,678 had acne on the face and 974 (54.05%) showed some degree of dissatisfaction. Regarding the impact of acne located on the chest, 326 out of 686 adolescents (47.52%) reported dissatisfaction. For acne located on the back, 568 out of 1,103 affected individuals (51.50%) showed dissatisfaction. Facial / dorsal acne and dissatisfaction were statistically associated with lower income, lower education levels and with non-whites. Presternal acne and dissatisfaction were statistically asssociated with lower income and lower education levels. CONCLUSION: This population-based study found a high prevalence of acne on the face, back and chest, with high rates of dissatisfaction. .

Acne vulgaris: prevalence and clinical forms in adolescents from São Paulo, Brazil

BACKGROUND: Acne is a common disease in adolescents, but there are no epidemiological data for acne in Brazil. OBJECTIVES: To estimate the prevalence and degree of acne in adolescents from Sao Paulo and study socio-demographic factors, family history and lifestyle, associated with the disease. METHODS: Cross-sectional study with 452 adolescents aged between 10 and 17 (mean=13.3 years), students from elementary and high school, examined by 3 independent evaluators. RESULTS: 62.4% were female, 85.8% white and 6.4% were aged 14. The prevalence was 96.0% and increased with age - all students over 14 had acne. The most prevalent form of acne was comedonal (61.1%), followed by mild (30.6%) and moderate (7.6%) papular-pustular, which affected mostly the face (97.5%). About half of the adolescents reported family history for acne in mother or father, and 20.6% reported previous treatment for acne. There was a higher chance of presenting non-comedonal acne with increased age (p<0.001). DISCUSSION: The prevalence of acne in adolescents varies widely due to the clinical features and diagnostic methods used. Adolescents whose brothers/sisters had acne (OR=1.7-p=0.027) and those over 13 (OR=8.3-p<0.001), were more likely to have non-comedonal acne. CONCLUSION: This study showed high prevalence of acne in adolescents from Sao Paulo, predominantly the comedonal form on the face, with a higher chance of presenting non-comedonal acne with increased age. .

Keratosis pilaris and prevalence of acne vulgaris: a cross-sectional study

BACKGROUND: Acne vulgaris has an important genetic predisposition, as well as keratosis pilaris. Clinical observations suggest that patients with keratosis pilaris have less frequent or less severe acne breakouts; however, we found no studies on this regard OBJECTIVE: To determine if the presence of keratosis pilaris is associated with lower prevalence and severity of acne. METHODS: A cross-sectional study was conducted with dermatology outpatients aged between 14 and 35 years. We evaluated history and clinical grade of acne, demographic variables, history of atopy, smoking, and use of hormonal contraceptives. Two groups were defined by the presence or absence of moderate to severe keratosis pilaris on the arms and were compared by bivariate analysis and by conditional multiple logistic regression. RESULTS: We included 158 patients (66% women), with a median age of 23±11 years. Twenty-six percent of them had keratosis pilaris, which was associated with a history of atopy (odds ratio [OR]=2.80 [1.36 to 5.75]; p<0.01). Acne was present in 66% of subjects, and was related to family history of acne (OR=5.75 [2.47 to 13.37]; p<0.01). In bivariate and multivariate analysis, the group with keratosis pilaris had a less frequent history of acne (OR=0.32 [0.14 to 0.70]; p<0.01). CONCLUSION: The presence of moderate to severe keratosis pilaris on the arms was associated with lower prevalence of acne vulgaris and lower severity of facial lesions in adolescents and young adults. .

Incidence of acne vulgaris in young adult users of protein-calorie supplements in the city of João Pessoa - PB / Incidencia de acne vulgar em adultos jovens usuarios de suplementos proteico-caloricos na cidade de Joao Pessoa - PB

BACKGROUND: Based on personal observations of dermatologists, nutritionists and patients, a new problem emerges in the gyms: development and exacerbation of acne in users of whey protein, which is a protein derived from cow's milk. Whey Protein extract contains growth factors that may be related to acne. Its purity and composition are not fully known and there is no scientific research on its potential to cause acne. OBJECTIVES: Assess the relationship between the use of proteincalorie supplements and onset or exacerbation of acne vulgaris in young adults in the city of João Pessoa. METHODS: Descriptive observational study conducted in gyms and in a dermatology clinic. Each participant was examined for acne on three occasions and followed for 60 days. RESULTS: 30 patients were examined. Onset or exacerbation of acneiform lesions were observed (p <0.0005). The effect was more prominent in females and in individuals without current acne and no family history of acne. CONCLUSION: This study showed the onset of acne with the progressive use of protein-calorie supplementation, in a two-month period. It is suggested that this type of supplementation be discouraged. .

FUNDAMENTOS: Na observação pessoal de dermatologistas, nutricionistas e dos próprios pacientes, um novo problema emerge nas academias de ginástica: desenvolvimento e exacerbação da acne em usuários de Whey Protein, proteínas derivadas do leite de vaca. Extratos de Whey Protein contêm fatores de crescimento que podem estar relacionados com a acne. Sua pureza e composição não são completamente conhecidas e não há investigações científicas sobre seu potencial causador de acne. OBJETIVO: Avaliar a relação entre o uso de suplementos protéico-calóricos e o aparecimento ou agravamento da acne vulgar em adultos jovens em João Pessoa - PB. MÉTODOS: Estudo observacional descritivo conduzido em academias de ginástica e em consultório de dermatologia. Cada participante foi examinado para acne em três ocasiões e acompanhado por 60 dias. RESULTADOS: Foram examinados 30 pacientes. Aparecimento ou exacerbação de lesões acneiformes foram observados (p<0,0005), sendo o efeito mais proeminente no sexo feminino e em indivíduos sem acne atual e sem história familiar de acne. CONCLUSÃO: Este estudo demonstrou o aparecimento de lesões acneiformes com o uso progressivo de suplementos proteico calóricos, ao longo de dois meses. Sugere-se que o uso deste tipo de suplemento seja desestimulado. .

The impact of acne vulgaris on quality of life and psychic health in young adolescents in Greece: results of a population survey / O impacto da acne vulgar na qualidade de vida e saúde psíquica em jovens adolescentes na Grécia: resultados de uma pesquisa populacional

BACKGROUND: Acne vulgaris can severely affect social and psychological functioning. OBJECTIVE: The aim of this study was to investigate the impact of acne vulgaris and its severity on Quality of Life of young adolescents in Greece. METHODS: We conducted a questionnaire based survey among 1560 adolescent between the ages of 11 and 19 years old and 1531 of these were completed. Adolescents with acne filled all the questions including the Children Dermatology Life Quality Index. Adolescents without acne filled the questions about age, family history of acne, stress and smoking. Data were analyzed with Pearson Chi Square test. RESULTS: Acne prevalence was 51.2% affecting both sexes equally. Self reported mild acne was present in 71.2% and moderate-severe acne in 28.8% of the study population. The mean age of the study population was 15.77y. The median score of Children Dermatology Life Quality Index was 4.02. The impact of acne on quality of life is associated with the severity of the acne (p<0.0001). Patients with moderate/severe acne experience greater psychosocial and emotional impairment (p<0.0001). Body image is modified proportionally to the severity of acne (p<0.0001). Symptoms and treatment of acne are factors that also influence their quality of life. Girls and boys are equally affected. Stress and heredity are correlated with acne and its severity (p<0.0001). We didn't find any correlation between smoking and acne. CONCLUSION: Acne affects Quality of Life of young adolescents in Greece. The impact is proportional to the severity of acne. More severe acne is associated with greater effect on quality of life with implications for self esteem, body image and relationships with others.

FUNDAMENTOS: Acne vulgar pode afetar seriamente o funcionamento social e psicológico. OBJETIVO: O objetivo deste estudo foi investigar o impacto da acne vulgar e sua gravidade na Qualidade de Vida de jovens adolescentes na Grécia. MÉTODOS: Nós conduzimos uma pesquisa baseada em questionário entre 1560 adolescentes com idades entre 11 e 19 anos e 1531 destes foram completados. Adolescentes com acne completaram todas as questões incluindo o Children Dermatology Life Quality Index (CDLQI). Adolescentes sem acne completaram as questões sobre idade, história familiar de acne, estresse e tabagismo. Os dados foram analisados pelo teste de chi-quadrado de Pearson. RESULTADOS: A prevalência de acne foi de 51.2%, afetando igualmente ambos os sexos. O auto relato de acne leve estava presente em 71.2% e de acne moderada a grave em 28.8% da população. A idade média da população em estudo foi de 15.77 anos. O escore médio do Children Dermatology Life Quality Index foi de 4.02. O impacto da acne na Qualidade de Vida está associado à gravidade da acne (p<0.0001). Pacientes com acne moderada/grave experimentam maior piora psico-social e emocional (p<0.0001). A imagem corporal é modificada proporcionalmente à gravidade da acne (p<0.0001). Sintomas e tratamento da acne são fatores que também influenciam sua qualidade de vida. Meninas e meninos são afetados igualmente. Estresse e hereditariedade estão correlacionados à acne e sua gravidade (p<0.0001). Nós não encontramos nenhuma correlação entre tabagismo e acne. CONCLUSÃO: Acne afeta a qualidade de vida de jovens adolescentes na Grécia. O impacto é proporcional à gravidade da acne. A acne mais grave está associada a um maior efeito na qualidade de vida com implicações na auto-estima, imagem corporal e relacionamento com outros.

Prevalence of Common Skin Diseases and Their Associated Factors among Military Personnel in Korea: A Cross-sectional Study

This study was conducted to clarify the prevalence of common skin diseases and their associated factors among military personnel in Korea. Four dermatologists visited adjacent military units and examined soldiers. A structured questionnaire that included questions about known skin diseases, demographic information, and questions for the Perceived Stress Index was completed for each participant. The soldiers that had been diagnosed with a skin disease answered one additional questionnaire (Skindex-29) which assess the influence of an individual's skin disease on daily life. Of 1,321 soldiers examined, 798 (60.4%) had one or more skin diseases. The three most common skin problems were acne (35.6%), tinea pedis (15.2%) and atopic dermatitis (5.1%). The diseases closely related to the period of military service were acne, tinea pedis, viral warts and corns. The diseases related to the amount of stress were atopic dermatitis, seborrheic dermatitis, and acne. The most troublesome skin diseases were atopic dermatitis, tinea cruris, and seborrheic dermatitis. These results demonstrated that the prevalence of skin disease among military personnel in Korea is very high, and that some of the skin disorders may have a significant influence on their daily lives.

Frequency and psychosocial impact of acne on university and college students

Objectives of the study were to describe the frequency of acne in late adolescent and adult students and to evaluate psychosocial impact of the disease. It was a cross-sectional study conducted in four institutions, from June to August 2008. Questionnaires with Cardiff Acne Disability Index [CADI] were filled by 950 students. They were examined for presence and severity of acne. Age ranged from 17 to 28 years. Frequency of facial acne was 74.6%. Difference between the genders was not statistically significant. Mean ADI score was 2.67 + 5.35, and range was 0-13. The disease had a greater psychosocial impact on females as compared to males

Acne da mulher adulta: aspectos epidemiológicos, diagnósticos e terapêuticos / Acne in adult women: epidemiological, diagnostic and therapeutic aspects

FUNDAMENTOS: A acne da mulher adulta (AMA) é uma dermatose de incidência crescente; o hiperandrogenismo está presente em muitos casos, mas há pacientes sem anormalidades hormonais. OBJETIVO: Analisar as características prevalentes na mulher adulta com acne sem hiperandrogenismo. MATERIAL E MÉTODO: Um levantamento de 226 prontuários com queixa de AMA foi realizado; 116 pacientes (51,3 por cento) possuíam perfil hormonal normal e, portanto, foram incluídas no estudo. Foram pesquisados idade, etnia, perfil clínico da acne, exames complementares, tratamentos anteriores, tratamentos prescritos e evolução. RESULTADOS: A média das idades foi de 33,9 anos e o grau clínico predominante foi o inflamatório moderado (grau II); a face foi a área mais acometida. Os retinoides tópicos foram as drogas mais prescritas, e a medicação sistêmica foi indicada em 53,4 por cento das pacientes. A regressão total foi observada em 31 pacientes (26,7 por cento) até 12 semanas de tratamento. Houve reação adversa ao tratamento tópico em 21,5 por cento das pacientes. CONCLUSÃO: O quadro clínico da AMA em pacientes sem hiperandrogenismo é de moderada intensidade, com predomínio de lesões inflamatórias. Seu tratamento é similar ao da acne vulgar; entretanto, atenção especial deve ser tomada com medicações de maior potencial irritante, uma vez que esse grupo parece ter uma maior predisposição a irritações cutâneas.

BACKGROUND: Adult female acne (AFA) is a dermatosis of increasing incidence; hyperandrogenism is present in many cases, but there are patients without hormonal abnormalities. OBJECTIVE: To analyze the prevalent characteristics in adult women with acne without hyperandrogenism. MATERIAL AND METHODS: A survey of 226 medical records with AFA complaints was conducted; of these, 116 (51.3 percent) had a normal hormonal profile and were, therefore, included in the study. We investigated age, ethnicity, clinical profile of acne, complementary exams, previous treatment, prescribed treatment and evolution. RESULTS: The mean age was 33.9 years and the predominant clinical grade of acne was moderate inflammatory (grade 2). The face was the most affected area. Topical retinoids were the most prescribed drugs, and systemic medication was prescribed to 53.4 percent of the patients. Total regression was observed in 31 patients (26.7 percent) within 12 weeks of treatment. Adverse reactions to topical treatment occurred in 21.5 percent of the patients. CONCLUSION: The clinical manifestations of AFA in patients without hyperandrogenism are moderate, with predominance of inflammatory lesions. Treatment is similar to that of acne vulgaris; however, special attention should be taken with more irritating medication since this group appears to be more predisposed to skin irritations.

prevalence of hirsutism in adolescent girls in yazd, central Iran

Hirsutism is a distressing problem especially among girls. This study was conducted to evaluate the prevalence of hirsutism and other hyper-androgenic symptoms in adolescent girls in Yazd, central Iran. Nine hundred high school girls [mean age of 17.26 and range of 15-19 years] were evaluated for prevalence of hirsutism and other hyper-androgenic syndromes. The selected girls were examined for the presence of hirsutism, acne, hypertrichosis, history of menstruation, and family history of known cases of hirsutism. Hirsutism was determined by the modified Ferriman-Gallwey index. Laboratory tests and ultrasound were requested for hirsute only. Among girls, 10.8% suffered from hirsutism. Other accompanying hyper-androgenic disorders were separately studied in two groups of hirsute and non-hirsute subjects. The most prevalent accompanying disorders were acne [42.7% vs 38.4%], hypertrichosis [42% vs 18.3%], first degree relatives' family history of hirsutism [25.5% vs. 7%], and menstrual irregularity [14.6% vs. 10.2%], respectively. In the hirsute group, based on the hormonal and ultrasound tests, the most prevalent revealed causes were polycystic ovary syndrome [60.8%], hyper-prolactinoma [7.2%], idiopathic hirsutism [28.9%], and undetermined [3.1%]. A high prevalence of hirsutism was observed which was more prevalent at higher ages in comparison to other societies showing that definition and scoring system of hirsutism need to be based on racial differences

Padrões clínicos de acne em mulheres de diferentes faixas etárias / Acne in women: clinical patterns in different age-groups

FUNDAMENTOS: Acne é dermatose comum que acomete ambos os gêneros e todas as faixas etárias. Mulheres apresentam diferentes padrões clínicos da doença, além de frequente persistência da acne após a adolescência. OBJETIVO: Analisar características clínicas e epidemiológicas associadas às diferentes faixas etárias acometidas por acne feminina. MÉTODOS: Estudo transversal envolvendo mulheres com diagnóstico de acne, atendidas em ambulatório de dermatologia geral. Variáveis relacionadas à doença e às pacientes foram avaliadas com o emprego de questionário padronizado. RESULTADOS: Avaliaram-se 103 pacientes, cuja idade média na época da consulta foi 21,7 ± 7,3 anos. Definiram-se dois subgrupos com idade de corte de 21 anos e idades médias de 15,8 ± 2,3 e 28,0 ± 5,1 anos. Houve correlação entre a duração do quadro e a idade das pacientes na consulta (R = 0,7). Observaram-se diferenças entre os grupos nas frequências de uso de contraceptivo oral combinado (OR = 48,1), lesões no colo (OR = 11,6), lesões no dorso (OR = 0,2), predominância na topografia superior da face (OR = 0,1) e idade de início das lesões (OR = 1,8). No grupo de mulheres adultas, 80 por cento relataram início do quadro antes dos 20 anos. CONCLUSÕES: Identificaram-se padrões clínicos cronológicos e topográficos que caracterizaram a acne feminina em diferentes faixas etárias, alertando para a importância da abordagem diagnóstica e terapêutica individualizada.

BACKGROUND: Acne is a frequent skin disease that occurs in both sexes and all age-groups. Women present several clinical disease patterns; moreover, persistence after adolescence is common. OBJECTIVE: To analyze clinical and epidemiological characteristics associated with different age-groups affected by acne in women. METHODS: Cross-sectional study involving female patients diagnosed with acne, at a general dermatology outpatient clinic. Variables related to disease and patients were assessed through a standardized questionnaire. RESULTS: One hundred and three women were assessed. The average age of patients at the time of the consultation was 21.7 ± 7.3 years. Two groups were defined (cut-off age of 21 years), with means of 15.8 ± 2.3 and 28.0 ± 5.1 years. There was correlation between disease duration and current age (R=0.7). There were group differences among frequencies of covariables: combined oral contraceptive (OR=48.1), lesions located on upper chest (OR=11.6), lesions on upper dorsum (OR=0.2), predominance on upper half of face (OR=0.1) and age at disease onset (OR=1.8). Among adult women, 80 percent reported acne onset before 20 years of age. CONCLUSION: Chronologic and topographic patterns of female acne in different age-groups were defined, reinforcing the importance of an individualized diagnostic and therapeutic approach.

Pattern of skin disorders among adolescent female students at Hyderabad, Sindh

To determine the pattern and severity of skin disorders among female adolescent students at Hyderabad, Sindh, Pakistan. This observational study was conducted at Hyderabad, Sindh, Pakistan, from August, 2007 to October, 2007. Four intermediate and degree colleges of the Hyderabad city were randomly selected and visited. The students were examined with regard to the type and severity of skin disorders. The findings were recorded on a pre-structured proforma. A total of 1350 students were examined. Their ages ranged from 16-24 years. Acne was the most common disorder seen in 59.5% of subjects followed by hair loss [59%], pigmentary disorders [36.3%], dandruff [26.1], hirsutism [20.9%], ephelides [6.4%], xerosis [2.9%], pityriasis versicolor [2.9%], pruritus [2.3%] and eczema [2.1%]. There were very few cases of pyoderma, tinea corporis and scabies. Skin disorders are common among adolescent college girls. The most prevalent group of skin disorders at this age is cosmetic one. Their proper management at earlier stages with education of patients is important to prevent late disfiguring complications and psychological sequelae

Treatment-Seeking Behaviors and Related Epidemiological Features in Korean Acne Patients

Little is known about the treatment-seeking behaviors of acne patients, especially Asian acne patients. This study was performed to obtain detailed information about the treatment-seeking behaviors in Korean acne patients. Patients who visited the dermatology departments at 17 university hospitals completed a self-administered questionnaire. Most patients obtained information about acne from doctors or the Internet. The most important criteria for selecting a treatment method or choosing a particular clinic were effectiveness and accessibility. Patients used traditional medicine, visited beauty clinics, drank more water, and used over-the-counter topical agents more frequently than they sought doctors during the worsening period. The degree of satisfaction in treatment was found to depend on the total cost of treatment, number of places visited, site affected by acne, and emotional stress. Those who had experienced a side effect tended to have been treated for longer, to have paid more for treatment, and to have an associated skin disease. Treatments prescribed by dermatology clinics had the lowest aggravating rate, although improvement rates for family medicine clinics were also fairly high. This is the first study to investigate in detail the demographic features and characteristics of the treatmentseeking behaviors of acne patients in Asia.

Frequency and magnitude of anxiety and depression among acne patients: a study of 100 cases

To see the frequency and magnitude of anxiety and depression amongst patients with acne. A cross sectional study. Out-patients departments of Psychiatry and Dermatology, Ziauddin Medical University, KDLB Campus, Karachi - Pakistan from 1[st] June 2005 till 31[st] August 2005. A total of 100 clinically diagnosed cases of acne belonging to both sexes and different age groups, fulfilling the inclusion criteria were enrolled. Only those patients were studied who could complete the Aga Khan University Anxiety and Depression Scale [AKUADS]. The "psychiatric scale scores" achieved by "AKUADS", indicated the probability of anxiety and depression in these patients. All the patients scoring 19 or above were labeled as suffering from anxiety and depression. All the findings were recorded, compiled, tabulated and analyzed. Of the 100 patients studied, there were 35 males [35%] and 65 females [65%]. The minimum age of presentation was 14 years and maximum 38, with a mean of 21.4 years. Mild acne was seen in 52%, followed by moderate in 35% and severe acne was a feature in 11%, while 2% cases had acne excoriee. The duration of the disease ranged in between 1 month to 10 years, with a mean of 38 months. Forty two of the patients studied manifested anxiety and depression with a score of or above 19 [AKUADS] accounting for 21% with moderate acne followed by mild acne [12%], severe [7%] and acne excoriee [2%] [P< 0.05]. Females accounted for 29% and males 13% of these patients. Patients with acne of recent onset had a mean score of 19, while those with a disease of at least 12 months had mean score 29. The patients with severe disease scored in the range of 24-38, moderate acne 19-26, mild acne 19-23 and acne excoriee 28. Acne has a probable association with anxiety and depression. Clinical variables of the disease and sociodemographics influence the magnitude of anxiety and depression in patients with acne