ABSTRACT
Abstract In the present work, twelve bacilli were isolated from four different regions of human skin from Bela population of Nagpur district, India. The isolated bacilli were identified by their morphological, cultural and biochemical characteristics. Seven isolates were Gram negative rods, out of which five were belong to genus Pseudomonas. Three among the five Gram positive isolates were identified as Dermabactor and the remaining two Bacillus. Their antimicrobial susceptibility profile was determined by Kirby-Bauer disc diffusion method. The isolates showed resistance to several currently used broad-spectrum antibiotics. The Dermabactor genus was resistant to vancomycin, although it was earlier reported to be susceptible. Imipenem was found to be the most effective antibiotic for Pseudomonas while nalidixic acid, ampicillin and tetracycline were ineffective. Isolates of Bacillus displayed resistance to the extended spectrum antibiotics cephalosporin and ceftazidime. Imipenem, carbenicillin and ticarcillin were found to be the most effective antibiotics as all the investigated isolates were susceptible to them. Antibiotic resistance may be due to the overuse or misuse of antibiotics during the treatment, or following constant exposure to antibiotic-containing cosmetic formulations.
Subject(s)
Adolescent/classification , Adolescent/drug effects , Adolescent/genetics , Adolescent/isolation & purification , Adolescent/microbiology , Adolescent/pharmacology , Adult/classification , Adult/drug effects , Adult/genetics , Adult/isolation & purification , Adult/microbiology , Adult/pharmacology , Anti-Bacterial Agents/classification , Anti-Bacterial Agents/drug effects , Anti-Bacterial Agents/genetics , Anti-Bacterial Agents/isolation & purification , Anti-Bacterial Agents/microbiology , Anti-Bacterial Agents/pharmacology , Bacillus/classification , Bacillus/drug effects , Bacillus/genetics , Bacillus/isolation & purification , Bacillus/microbiology , Bacillus/pharmacology , Female/classification , Female/drug effects , Female/genetics , Female/isolation & purification , Female/microbiology , Female/pharmacology , Healthy Volunteers/classification , Healthy Volunteers/drug effects , Healthy Volunteers/genetics , Healthy Volunteers/isolation & purification , Healthy Volunteers/microbiology , Healthy Volunteers/pharmacology , Humans/classification , Humans/drug effects , Humans/genetics , Humans/isolation & purification , Humans/microbiology , Humans/pharmacology , Male/classification , Male/drug effects , Male/genetics , Male/isolation & purification , Male/microbiology , Male/pharmacology , Microbial Sensitivity Tests/classification , Microbial Sensitivity Tests/drug effects , Microbial Sensitivity Tests/genetics , Microbial Sensitivity Tests/isolation & purification , Microbial Sensitivity Tests/microbiology , Microbial Sensitivity Tests/pharmacology , Middle Aged/classification , Middle Aged/drug effects , Middle Aged/genetics , Middle Aged/isolation & purification , Middle Aged/microbiology , Middle Aged/pharmacology , Skin/classification , Skin/drug effects , Skin/genetics , Skin/isolation & purification , Skin/microbiology , Skin/pharmacology , Young Adult/classification , Young Adult/drug effects , Young Adult/genetics , Young Adult/isolation & purification , Young Adult/microbiology , Young Adult/pharmacologyABSTRACT
The bacterium, Inquilinus limosus, with its remarkable antimicrobial multiresistant profile, has increasingly been isolated in cystic fibrosis patients. We report draft genome sequence of a strain MP06, which is of considerable interest in elucidating the associated mechanisms of antibiotic resistance in this bacterium and for an insight about its persistence in airways of these patients.