ABSTRACT
O hemangiossarcoma ocular na espécie equina é um tumor maligno, raro e agressivo, de origem vascular endotelial. No presente trabalho, descreve-se um caso de hemangiossarcoma ocular em uma égua de 10 anos que apresentava secreção serossanguinolenta advinda de uma massa, acometendo a conjuntiva bulbar e a terceira pálpebra do olho direito. O diagnóstico foi realizado com base na avaliação histopatológica e na imuno-histoquímica. Foi realizada a enucleação, assim como a completa excisão cirúrgica do tecido acometido, não sendo observada, após seis meses da terapia, a recidiva ou a metástase da lesão.
Equine ocular hemangiosarcoma is a rare and aggressive malignant tumor of vascular endothelial origin. We describe a case of ocular hemangiosarcoma in a 10-year-old mare with serosanguineous secretion arising from a mass involving the bulbar conjunctiva and third eyelid of the right eye. The diagnosis was based on histopathological evaluation and immunohistochemistry. Enucleation was performed as complete surgical excision of the affected tissue, with no recurrence or metastasis of the lesion being observed after six months of.
Subject(s)
Animals , Eye Enucleation/veterinary , Hemangiosarcoma/veterinary , Vascular Neoplasms/diagnosis , Vascular Neoplasms/veterinary , Eyelid Diseases/veterinary , Vascular System Injuries/veterinary , Neoplasm MetastasisABSTRACT
It was reported a case of a 9-year-old Brazilian Fila male dog that had been affected by a tissular formation of the nictitant membrane of the right eye with four months of evolution. Conjunctival hyperemia and edema, serosanguinolent secretion, and a conjunctival neoformation at the nictitant membrane were observed. Surgical exeresis of the neoformation was performed. Endothelial cells slightly differentiated and pleomorphic, with an intense vascular neoformation compatible to nictitant membrane hemangiosarcoma, were found at the histological exam.
Relata-se o caso de um cão, macho, da raça Fila Brasileiro, com nove anos de idade, acometido por neoformação tecidual na membrana nictitante do olho direito, com cerca de quatro meses de evolução. Realizou-se exame oftálmico rotineiro, a partir do qual se notaram hiperemia e edema conjuntivais, secreção ocular serossangüinolenta e neoformação saliente na conjuntiva da membrana nictitante. Realizou-se a exérese cirúrgica da neoformação. À histopatologia, encontraram-se células endoteliais pouco diferenciadas e pleomórficas que originavam intensa neoformação vascular, compatíveis com hemangiossarcoma da membrana nictitante.
Subject(s)
Animals , Male , Dogs , Dogs/anatomy & histology , Eyelid Diseases/pathology , Eyelid Diseases/veterinary , Hemangiosarcoma/pathology , Hemangiosarcoma , Hemangiosarcoma/veterinary , Nictitating Membrane/abnormalitiesABSTRACT
The objective of this research was to present an experimental model for the prolapse of the third eyelid gland in male, adult mongrel dogs by the use of a periorbital glandular support conjunctiva tissue resection followed by macro and microscopic assessments. Length, thickness and width of normal glands were statistically studied at baseline and then again after a period of 30 days of exposition. In relation to the experimental model, 84.21 percent of glands, which underwent the resection of the conjunctiva support tissue, support tissue, remained protusioned. There were significant differences between normal and protusioned glands. Protusioned glands were larger in respect to length, thickness and width. For the microscopy studies, two experimental groups were established: non-treated protusioned glands (GI); and buried protusioned glands (GII). Glandular, conjunctiva tissue, and duct alterations were studied in both groups. Through the results obtained by the Schirmer's test, it was evidenced that the lachrymal production decreased when compared to the normal ones not protusioned, especially in those cases where the protusioned glands were not buried.
Neste trabalho, propõe-se um modelo experimental de protrusão da glândula da terceira pálpebra em cães mestiços, machos adultos e valendo-se da ressecção do retináculo glandular periorbitário e de avaliações macro e microscópicas. Foram estudadas, a estatística, o comprimento, a espessura e a largura de glândulas normais e após um período de 30 dias de exposição. Relativamente ao modelo experimental, 84,2 por cento das glândulas em que foi realizada a ressecção do retináculo permaneceram protruídas. Houve diferença significativa entre as glândulas normais e as protruídas. As glândulas protruídas aparentaram-se maiores quanto ao comprimento, à espessura e à largura. Para estudos à microscopia, constituíram-se dois grupos experimentais: glândulas protruídas não-tratadas (GI) e glândulas protruídas sepultadas (GII). Estudaram-se as alterações ductais, as glandulares e as conjuntivais em ambos os grupos. Os resultados mostraram que glândulas protruídas não-tratadas apresentaram maior porcentagem de alterações inflamatórias, glandulares e ductais. Mediante análise do teste de Schirmer I, constatou-se que a produção lacrimal diminuiu, quando comparada às glândulas normais não-prolapsadas, notadamente nos casos em que as glândulas prolapsadas não foram sepultadas.
Subject(s)
Animals , Male , Dogs , Lacrimal Apparatus , Dog Diseases , Eyelid Diseases/veterinary , Nictitating MembraneABSTRACT
Entropion is defined as the inward rolling of the eyelid margin in which the eyelashes and eyelid hair (frequently the lower lateral lid) rub the cornea. Etiologies may be congenital, spastic, or cicatricial. This condition usually causes epiphora, blepharospasm, photophobia, conjunctivitis, purulent discharge, corneal vascularization, pigmentation and ulceration, if not surgically treated. Congenital entropion commonly affects dogs and is frequently hereditary in some breeds, whereas cats are uncommonly affected. A predilection for the Persian breed to present primary entropion has been suggested. The authors report two cases of entropion in Persian cats referred to the Ophthalmology Section of Veterinary College of Säo Paulo State University - UNESP, Jaboticabal - SP / Brazil. First case: a male Persian cat, 2 years old, with a history of bilateral ocular irritation and purulent discharge for 8 months. Ophthalmic examination revealed epiphora, blepharospasm, photophobia, bilateral entropion affecting the whole length of the lower eyelids, conjunctivitis and purulent discharge. Second case: a male Persian cat, 1 year old, with a history of bilateral ocular irritation and purulent discharge for 3 weeks. At ophthalmic examination the animal was presenting epiphora, blepharospasm, photophobia, bilateral entropion affecting the whole length of the lower lids, conjunctivitis, purulent discharge, corneal vascularization, superficial ulceration and edema. The entropion persisted after topical anaestesia in both cats. Surgical treatment was similar in both cases, based on the modified Holtz-Celsus procedure. Grid keratotomy procedure was also performed in the second case. Both cats had a satisfactory clinic evolution which was confirmed few days after surgery.