ABSTRACT
Se presenta el primer caso de fungemia por una especie de Candida relacionada con Candida pseudorugosa. La identificación de las especies de levaduras es de importancia a nivel epidemiológico y para el tratamiento de los pacientes que cursan una infección por levaduras.
Subject(s)
Humans , Female , Middle Aged , Candida/classification , Candida/pathogenicity , Fungemia/complications , Fungemia/diagnosis , Fungemia/therapy , Yeasts/classification , Yeasts/pathogenicityABSTRACT
Galactosemia is one of the rare inborn errors of metabolism, which if detected early can be treated effectively. Galactosemic infants have a significant increased risk of developing sepsis. E. coli sepsis is a known entity, and also an important cause of early mortality in these children. But fungal sepsis in these patients is rarely reported. Here is a case of 45 day-old child who presented with fungal sepsis, which on investigation turned out to be galactosemia.
Subject(s)
Antifungal Agents/therapeutic use , Candida/isolation & purification , Fluconazole/therapeutic use , Fungemia/complications , Fungemia/genetics , Fungemia/microbiology , Fungemia/therapy , Galactosemias/complications , Galactosemias/diagnosis , Galactosemias/genetics , Galactosemias/therapy , Genetic Heterogeneity , Humans , Infant , Male , Mutation , Soy Milk , Treatment OutcomeABSTRACT
Foi realizado um estudo para verificar a ocorrência de leveduras do gênero Rhodotorula, em hemocultura por um período de 8 anos. Os pacientes identificados foram descritos clinicamente segundo variáveis de interesse incluindo dados sobre terapêutica e desfecho. Determinou-se também as concentrações inibitórias mínimas de 20 cepas frente a diferentes antifúngicos de acordo com NCCLS e EUCAST. Realizou-se tipagem molecular através da cariotipagem eletroforética em campo pulsátil.
A study was conducted to verify the frequency of occurrence of Rhodotorula spp. from blood cultures over an 8-year period, clinically and microbiologically characterizing patients affected, including data regarding antifungal treatment and outcome. The minimal inhibitory concentrations of antifungal agents were determined against 20 isolates. Molecular typing of the strains were performed using pulsed field gel electrophoresis method.