permeability of the enteric ganglia of the guinea-pig distal colon to intravenously injected horseradish peroxidase

In this work, the permeability of the "Capsule" of enteric ganglia to intravenously injected horseradish peroxidase [HRP] has been studied in the guinea-pig distal colon. The study was conducted at 30, 90 minutes and 6 hours following injection. HRP rapidly penetrated the walls of submucosal blood vessels and to a must lesser extent those of the myenteric zone. HRP reaction product was subsequently found more within the submucous ganglia than within the myenteric ganglia. HRP within both types of ganglia was more prominent 6 hours following injection