ABSTRACT
With the increasing incidence of upper gastric cancer and early gastric cancer, surgeons have gradually paid attention to the selection of appropriate digestive tract reconstruction methods. At present, the safety of surgery is no longer the main aim pursued by surgeons, and the focus of surgery has gradually changed to postoperative quality of life. Surgical procedures for upper gastric cancer include total gastrectomy (TG) and proximal gastrectomy (PG). Roux-en-Y anastomosis is recommended for digestive tract reconstruction after TG. The classic method of digestive tract reconstruction after PG is distal residual stomach and esophageal anastomosis. However, to prevent esophageal reflux caused by PG, a lot of explorations have been carried out over the years, including tubular gastroesophageal anastomosis, double-flap technique (Kamikawa anastomosis), interposition jejunum, double-tract reconstruction and so on. But the appropriate method of digestive tract reconstruction for upper gastric cancer is still controversial. In this paper, based on literatures and our clinical experience, the selection, surgical difficulties and techniques of digestive tract reconstruction after PG are discussed.
Subject(s)
Humans , Anastomosis, Roux-en-Y/methods , Anastomosis, Surgical/methods , Gastrectomy/methods , Gastric Stump/surgery , Quality of Life , Retrospective Studies , Stomach Neoplasms/surgery , Treatment OutcomeABSTRACT
ABSTRACT Background: remnant gastric cancer (RGC) develops five years or later after previous resection for benign or malignant lesion. The treatment is performed through completion total gastrectomy (CTG) with radical lymphadenectomy. Some reports consider this procedure may be associated with higher rates of morbidity and mortality. Objective: to evaluate surgical results and survival after CTG in patients with RGC. Methods: 54 patients who underwent CTG between 2009 and 2019 were included in the study. As a comparison group 215 patients with primary gastric cancer (PGC) who underwent total gastrectomy (TG) in the same period were selected. Results: among the initial characteristics, age (68.0 vs. 60.5; p<0.001), hemoglobin values (10.9 vs. 12.3; p<0.001) and body mass index (22.5 vs. 24.6; p=0.005) were different between the RGC and PGC groups, respectively. The most frequent postoperative complications were related to pulmonary complications, infection and fistula in both groups. There was a higher incidence of esophagojejunal fistula in the CTG group (14.8% vs 6.5%, p=0.055). Perioperative mortality was higher in RGC patients (9.3% vs. 5.1%), but without significance (p=0.329). Hospital length of stay, postoperative complications graded by the Clavien-Dindo classification, mortality at 30 and 90 days were not different between groups. There was no significant difference in disease-free and overall survival between RGC and PGC groups. Conclusion: despite previous reports, surgical results and survival were similar between groups. Higher risk of esophagojejunal fistula must be considered.
RESUMO Antecedentes: o câncer do coto ou remanescente gástrico (CRG) se desenvolve cinco anos ou mais após a ressecção gástrica por lesão benigna ou maligna. O tratamento é realizado através da gastrectomia total complementar (GTC) com linfadenectomia. Alguns relatos consideram que esse procedimento pode estar associado a maiores taxas de morbimortalidade. Objetivo: avaliar os resultados cirúrgicos e a sobrevida após GTC em pacientes com CRG. Métodos: 54 pacientes submetidos a GTC entre 2009 e 2019 foram incluídos no estudo. Como grupo de comparação, foram selecionados 215 pacientes com câncer gástrico primário (CGP) submetidos à gastrectomia total (GT) no mesmo período. Resultados: dentre as características iniciais, a idade média (68,0 vs. 60,5; p <0,001), os valores de hemoglobina (10,9 vs. 12,3; p <0,001) e o índice de massa corporal (22,5 vs. 24,6; p = 0,005) diferiram entre os grupos CRG e CGP, respectivamente. As complicações pós-operatórias mais frequentes foram pulmonares, infecciosas e fístulas nos dois grupos. Houve maior incidência de fístula esofagojejunal no grupo GTC (14,8% vs 6,5%, p = 0,055). A mortalidade perioperatória foi maior nos pacientes com CRG (9,3% vs. 5,1%), mas sem significância (p = 0,329). O tempo de internação hospitalar, complicações pós-operatórias (Clavien-Dindo), mortalidade aos 30 e 90 dias não foram diferentes entre os grupos. Não houve diferença significativa na sobrevida livre de doença e global entre os grupos CRG e CGP. Conclusão: apesar dos relatos anteriores, os resultados cirúrgicos e a sobrevida foram semelhantes entre os grupos. Maior risco de fístula esofagojejunal dever ser considerado.
Subject(s)
Humans , Stomach Neoplasms/surgery , Gastric Stump/surgery , Gastrectomy , Lymph Node Excision , Postoperative Complications/epidemiology , Stomach Neoplasms/mortality , Stomach Neoplasms/pathology , Brazil/epidemiology , Survival Analysis , Incidence , Survival Rate , Retrospective Studies , Gastric Stump/pathologyABSTRACT
CONTEXT: Gastric stump cancer after gastric resection is a well-known disease. It may be a newly developed cancer after resection due to benign disease, or recurrent or residual disease after oncological surgery. The predominant histological type is usually adenocarcinoma. This study aimed to report on a rare occurrence of a mixed adenoneuroendocrine carcinoma (MANEC) on the gastric stump. CASE REPORT: The case of an 83-year-old female who presented a locally aggressive gastric stump MANEC, 35 years after Billroth II gastrectomy to treat a peptic ulcer, is reported. The patient underwent resection and adjuvant therapy. She has been followed up for one year without signs of recurrence. CONCLUSION: MANEC is a rare type of gastrointestinal neoplasm. The classification, histopathology, clinical features, treatment issues and prognosis are discussed along with a brief review of the literature.
CONTEXTO: O câncer de coto gástrico após gastrectomia é uma condição extensamente documentada. Pode se tratar de doença desenvolvida após a ressecção por doença benigna, ou ainda doença recorrente ou residual após cirurgia oncológica. Geralmente, o tipo histológico predominante é o adenocarcinoma. Este estudo tem como propósito relatar a rara ocorrência de um adenocarcinoma neuroendócrino misto (MANEC) no coto gástrico. RELATO DE CASO: É relatado o caso de uma mulher de 83 anos que apresentou um MANEC localmente agressivo 35 anos após uma gastrectomia à Billroth II devido a úlcera péptica. Foi submetida a ressecção e terapia adjuvante e foi seguida por 12 meses sem sinais de recorrência. CONCLUSÃO: Os MANECs constituem raro tipo de neoplasia gastrointestinal. Sua classificação, histopatologia, aspectos clínicos, tratamento e prognóstico são discutidos junto com uma breve revisão de literatura.
Subject(s)
Humans , Female , Aged, 80 and over , Stomach Neoplasms/surgery , Adenocarcinoma/surgery , Mixed Tumor, Malignant/surgery , Carcinoma, Neuroendocrine/surgery , Gastric Stump/surgery , Stomach Neoplasms/therapy , Gastroenterostomy , Adenocarcinoma/therapy , Mixed Tumor, Malignant/therapy , Carcinoma, Neuroendocrine/therapy , Chemoradiotherapy, Adjuvant/methodsABSTRACT
La pancreatogastroanastomosis (PG) es una de las alternativas en la reconstrucción del muñón pancreático luego de una pancreatoduodenectomía (PD). Descrita en 1946, sólo ha cobrado popularidad en los últimos 10 años. Pareciera que esta modalidad de reconstrucción pancreática se asocia con menor incidencia de filtración de la anastomosis y, con ello, menos morbi-mortalidad relacionada al procedimiento. En este trabajo se presentan los detalles técnicos involucrados en este procedimiento, los resultados clínicos obtenidos y su impacto en la actitud hacia la PD por parte de los cirujanos de nuestro servicio
Subject(s)
Humans , Anastomosis, Surgical/methods , Pancreatic Neoplasms , Pancreaticoduodenectomy , Gastrostomy , Gastric Stump/surgery , Postoperative Complications , Plastic Surgery Procedures/methodsABSTRACT
Pacientes submetidos a radioterapia pélvica poderäo necessitar de derivaçöes urinárias, seja por recidiva local, estenose ureteral ou cistite actínica grave. A maioria das técnicas descritas para a confecçäo de reservatórios continentes exigem o emprego de segmentos íleocolônicos que sofrem igualmente os efeitos deletérios da irradiaçäo. Nesta situaçäo, o estômago tem sido nova opçäo primária. Os autores relatam dois casos em que houve falha no uso de tecido gástrico na reconstruçäo urinária pós-radioterapia, discutem uma proposta alternativa para resoluçäo desta situaçäo, aspectos técnicos envolvidos e os resultados iniciais
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Gastric Stump/surgery , Urinary Diversion/rehabilitation , Pelvis/radiation effects , Plastic Surgery Procedures , Colectomy/rehabilitation , Gastrectomy/rehabilitationABSTRACT
Se revisan diferentes aspectos del problema que incluye el riesgo estimado post-cirugía gástrica, la relación del cáncer primario de muñón gástrico (CPMG) con el tipo de cirugía gástrica, la localización más frecuente, los aspectos histopatológicos, la patogenia, sintomatología y diagnóstico y la racionalización del tratamiento quirúrgico. Se concluye de esta revisión que no se conoce la prevalencia real del CPMG y el hecho de que la gran mayoría de las veces se diagnostica cuando el tumor está en fase avanzada
Subject(s)
Humans , Gastric Stump/surgery , Gastric Stump/physiopathology , Gastric Stump/pathology , Stomach Neoplasms/epidemiology , Stomach Neoplasms/physiopathology , Stomach Neoplasms/therapyABSTRACT
Among a series of 266 cases of gastric cancer operated on between 1981 and 1991, 8 cases were developed on gastric stump after gastro-duodenal surgery. A post operative delay of 10 years has been insisted upon. We noticed an exclusive masculine serie. The main age was 61 years. Clinical aspects were univoque and treatment was always surgical with a resecability rate of 37%. Pathological analysis of operatory specimen and biopsies has shown everywhere an adenocarcinoma. The only way to improve prognosis is based on early histoendoscopic supervision since the tenth year after initial intervention of these operated patients of the stomach with high neoplasic risk