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1.
Rev. chil. cir ; 68(1): 32-37, feb. 2016. ilus, tab
Article in Spanish | LILACS | ID: lil-780530

ABSTRACT

Abstract Introduction: Keloids and hypertrophic scars are dermal fibro-proliferative disorders unique to humans. Their treatment is a true challenge with multiple options, but not all the time with good results. Unfortunatelythis problem is not uncommon in patients with history of burn injury. Aim: To evaluate use of verapamil andpressure garments in patients with hypertrophic or keloid scar caused by burn injury. methods: We includedpatients with a hypertrophic or keloid scar caused by burn injury that report non-response to treatment withpressure garment. The pathologic scars were evaluated by serial photographic records, Vancouver and Posasscales. The scales of Vancouver and Posas were compared with t Student. Results: We included 13 scars in11 patients. Four scars were located in the legs, 4 in the arms, 4 in the face-neck and 1 in the abdomen. Thedose of verapamil was calculated 0.03 mg per kg. Injections were scheduled every 7 to 10 days until complete 6 sessions. Taking in count Posas scale, patients referred improvement in pigmentation (0.01), thickness(0.005), pliability (0.01), pruritus (0.003) and irregular surface (0.004). In the Vancouver scale the observers mentioned improvement in elevation (0.008), pigmentation (0.014), vascularity (0.022) and flexibility (0.014).No adverse effects were found in verapamil injection. Conclusion: Verapamil was useful in conjunction withpressure garment to improve the condition of the keloid and hypertrophic scar caused by burn.


Resumen Introducción: La cicatriz queloide o la cicatriz hipertrófica son desórdenes fibro-proliferativos únicos de los humanos, cuyo tratamiento representa un reto en donde existen pocas opciones con buenos resultados.Objetivo: Evaluar el uso de verapamilo y las prendas de compresión en pacientes con cicatrización patológicacomo consecuencia de quemadura. material y método: Incluimos pacientes con cicatrización patológica,ya sea queloide o hipertrófica, causada por quemadura que mencionaron no haber tenido beneficio con el usode prendas de compresión. La cicatriz fue evaluada con fotografías seriadas, escala de Vancouver y Posas.Los resultados fueron comparados con la prueba de t de Student. Resultados: Incluimos 13 cicatrices en 11pacientes. La localización de las cicatrices fue en brazos 4, piernas 4, cara y cuello 1, y abdomen 1. La dosisde verapamilo se calculó a 0,03 mg por kg. Las inyecciones se aplicaron intralesionales y se administraroncada 7 a 10 días hasta completar 6 sesiones. Encontramos mejoría en los siguientes parámetros de la escalade Posas: pigmentación (0,01), pliabilidad (0,01), endurecimiento o grosor (0,005), prurito (0,003) e irregular (0,004). En la escala de Vancouver elevación (0,008), pigmentación (0,014), vascularidad (0,022) yflexibilidad (0,014). No encontramos efectos adversos con la administración de verapamilo. Conclusión: Elverapamilo fue útil en conjunto con las prendas de compresión para mejorar las condiciones de la cicatrizqueloide e hipertrófica causadas por lesiones por quemadura.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Verapamil/therapeutic use , Cicatrix, Hypertrophic/therapy , Compression Bandages , Keloid/therapy , Burns/complications , Prospective Studies , Cicatrix, Hypertrophic/etiology , Keloid/etiology
2.
Rev. méd. Chile ; 134(10): 1322-1329, oct. 2006. ilus, tab
Article in Spanish | LILACS | ID: lil-439927

ABSTRACT

The presence of mutilations in the form of tattooing and body piercing is becoming increasingly common in adolescents, a practice that is not free of risk. Reported complications include local infections, bleeding, tearing, hypersensitivity reactions, transfusion-transmitted diseases (hepatitis B virus, hepatitis C virus, HIV, syphilis), Chagas' disease and infective endocarditis. On the other hand, several studies have demonstrated an association between body modifications and high-risk behavior in adolescents, as alcohol or drug abuse, cigarette smoking, violence and schooling problems. There is also an association with depression, suicide, eating disorders and other psychophysiologic disorders. This is a review of body modifications in adolescents, emphasizing in the risks, complications and motivations of this practice.


Subject(s)
Adolescent , Adult , Child , Humans , Adolescent Behavior/physiology , Body Piercing/adverse effects , Risk-Taking , Tattooing/adverse effects , Bacterial Infections/etiology , Dermatitis, Contact/etiology , Keloid/etiology , Papillomavirus Infections/etiology , Safety
4.
Arch. argent. dermatol ; 47(6): 279-86, nov.-dic. 1997. ilus
Article in Spanish | LILACS | ID: lil-209909

ABSTRACT

Se hace referencia a la distinción entre cicatrización y cicatriz y la clasificación según el origen de esta última. Se pasa breve revista a los factores generales y locales que intervienen como complicación de la cicatrización. Se mencionan en forma de cuadro sinóptico las tres fases en que se divide el proceso de cicatrización y su tiempo de duración. Se dividen las cicatrices en viciosas y patológicas. Las primeras se definen como exageración del proceso normal de cicatrización y de las segundas, que son una neopatología, se hace referencia especial al queloide, diferenciándola de la cicatriz hipertrófica, que es una cicatriz viciosa. Breve referencia a un trabajo de investigación personal de 1966 sobre "Primeras etapas de la histogénesis del queloide provocado" y su conclusión. Se pasa revista a factores locales y generales que intervendrían en la formación de un queloide. Para concluir se formulan reglas elementales de la Cirugía dermatológica para lograr una buena cicatriz quirúrgica


Subject(s)
Humans , Cicatrix/classification , Wound Healing/physiology , Keloid/physiopathology , Wound Healing/physiology , Keloid/diagnosis , Keloid/etiology
5.
In. Pinto, Leäo Pereira; Souza, Lélia Batista de; Freitas, Roseana de Almeida; Figueiredo, Cláudia Roberta Leite Vieira de; Galväo, Hébel Cavalcanti; Câmara, Maria Leonor Assunçäo Soares; Carvalho, Rejane Andrade de. Patologia básica: sinopse. Natal, EDUFRN, 1997. p.114-23.
Monography in Portuguese | LILACS, BBO | ID: lil-246581
7.
Assiut Medical Journal. 1992; 16 (4): 123-30
in English | IMEMR | ID: emr-23134

ABSTRACT

There is suspicion that Keloids arise as a result of immune reaction and the immune system was implicated in Keloid formation. This study included 80 patients with hypertrophic scars or Keloids, 34 were males and 46 were females, their ages ranged between 10 and 60 years [22.7 +/- 11.3] and 20 of closely matched population as a control group. Serum immunoglobulins [IgA, IgM and IgG] were estimated in the two groups by an immunodiffusion technique. There was a significant increase in the serum immunoglobulins in the patients with hypertrophic scars or Keloids than that of the control group, which may suggest the implication of the immune system in the formation of hypertrophic scars and keloids


Subject(s)
Keloid/etiology , Cicatrix/etiology , Immune System/physiology
8.
Indian J Cancer ; 1983 Jan-Feb; 20(1): 27-31
Article in English | IMSEAR | ID: sea-51151
9.
Indian J Ophthalmol ; 1975 Jul; 23(2): 18-9
Article in English | IMSEAR | ID: sea-70526
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