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1.
Motriz (Online) ; 25(3): e101995, 2019. tab, graf
Article in English | LILACS | ID: biblio-1040649

ABSTRACT

Aim: Surface electromyography (sEMG) has been established as a safe non-invasive method to investigate neuromuscular function. However, the use of this instrument to assess lower limbs of transfemoral amputees still presents a lack of standardization in its methods of signal acquisition and processing. The aim of this study was to review the current state of sEMG utilization to assess transfemoral amputees, the procedures adopted for the acquisition and the functional findings. Methods: This is a literature review. Five electronic databases were searched to find the studies: All relevant information of each study was extracted and registered. Methodological quality was evaluated using a customized checklist. Results: Eight studies followed the inclusion criteria and were included in this paper. Four studies did not reach more than 80% of the quality checklist, few studies fully described the methodology applied. The muscles assessed were similar in all studies, electrodes placement was determined by different criteria. Conclusion: This paper demonstrates that a few studies have used this method to assess this population and the main variable aspect is concerned to the placement of the electrodes. More researches are needed to better understand the neuromuscular behavior of amputees by using sEMG and assist future researches to develop more reproducible and reliable studies.(AU)


Subject(s)
Humans , Electromyography/instrumentation , Hip/physiopathology , Amputation, Surgical , Knee/physiopathology
2.
Rev. bras. reumatol ; 57(1): 37-44, Jan.-Feb. 2017. tab, graf
Article in English | LILACS | ID: biblio-844204

ABSTRACT

ABSTRACT Background: Secondary hyperalgesia in individuals with less severe levels of knee osteoarthritis remains unclear. The objective of this study was to measure the pressure pain threshold of individuals with mild or moderate knee osteoarthritis and compare with no osteoarthritis. Methods: Ten healthy controls and 30 individuals with mild or moderate knee osteoarthritis divided into two groups (unilateral and bilateral involvement) were included. Dermatomes in lumbar levels (L1, L2, L3, L4 and L5) and sacral level (S1 and S2), myotomes (vastus medialis, vastus lateralis, rectus femoris, adductor longus, tibialis anterior, peroneus longus, iliacus, quadratus lumborum, and popliteus muscles), and sclerotomes in lumbar levels (L1-L2, L2-L3, L3-L4, L4-L5 supraspinous ligaments), over the L5-S1 and S1-S2 sacral areas, pes anserinus bursae, and at the patellar tendon pressure pain threshold were assessed and compared between individuals with and without knee osteoarthritis. Results: Knee osteoarthritis groups (unilateral and bilateral) reported lower pressure pain threshold compared to the control group in most areas (dermatomes, myotomes, and sclerotomes). There were no between group differences in the supra-spinous ligaments and over the L5-S1 and S1-S2 sacral areas of the sclerotomes. No difference was seen between knee osteoarthritis. Conclusion: These findings suggest that individuals with mild to moderate knee osteoarthritis had primary and secondary hyperalgesia, independent of unilateral or bilateral involvement. These results suggest that the pain have to be an assertive focus in the clinical practice, independent of the level of severity or involvement of knee osteoarthritis.


RESUMO Introdução: A ocorrência de hiperalgesia secundária em indivíduos com níveis menos graves de osteoartrite de joelho ainda é incerta. O objetivo deste estudo foi medir o limiar de dor à pressão (LDP) de indivíduos com osteoartrite de joelho (OAJ) leve ou moderada e comparar com indivíduos sem osteoartrite. Métodos: Foram incluídos 10 controles saudáveis e 30 indivíduos com OAJ leve ou moderada, divididos em dois grupos (envolvimento unilateral e bilateral). Foi avaliado e comparado o LDP em dermátomos (L1, L2, L3, L4, L5, S1 e S2), miótomos (músculos vasto medial, vasto lateral, reto femoral, adutor longo, tibial anterior, fibular longo, ilíaco, quadrado lombar e poplíteo) e esclerótomos (ligamentos supraespinais L1-L2, L2-L3, L3-L4, L4-L5), sobre as áreas sacrais L5-S1 e S1-S2, bolsa anserina e tendão patelar entre os indivíduos com e sem OAJ. Resultados: Os grupos OAJ (unilateral e bilateral) relataram menor LDP em comparação com o grupo controle na maior parte das áreas (dermátomos, miótomos e esclerótomos). Não houve diferenças entre os grupos nos ligamentos supraespinais e ao longo das áreas sacrais L5-S1 e S1-S2 dos esclerótomos. Não foi observada qualquer diferença entre os indivíduos com OAJ. Conclusão: Esses achados sugerem que os indivíduos com OAJ leve a moderada tinham hiperalgesia primária e secundária, independentemente do acometimento unilateral ou bilateral. Esses resultados sugerem que a dor precisa ser um foco assertivo na prática clínica, independentemente do grau de gravidade ou envolvimento da OAJ.


Subject(s)
Humans , Male , Female , Aged , Pressure/adverse effects , Pain Threshold/physiology , Osteoarthritis, Knee/complications , Hyperalgesia/etiology , Knee/physiopathology , Health Surveys , Osteoarthritis, Knee/physiopathology , Disability Evaluation , Trigger Points , Hyperalgesia/physiopathology , Knee/innervation , Middle Aged
3.
Rev. bras. queimaduras ; 15(4): 261-266, out. - dez. 2016. graf
Article in Portuguese | LILACS | ID: biblio-915187

ABSTRACT

bjetivo: Avaliar a amplitude de movimento de indivíduos com sequelas de queimadura e a interferência na capacidade funcional. Método: Esta pesquisa foi do tipo transversal, descritiva e de campo, sendo a amostra selecionada por conveniência, consistindo de um estudo piloto. Utilizou-se o flexímetro Sanny para avaliação da amplitude de movimento e a Medida de Independência Funcional para avaliação da capacidade funcional do paciente queimado, seguindo um protocolo de avaliação confeccionado pelas próprias pesquisadoras. Este estudo foi realizado em um Centro de Reabilitação, incluindo-se pacientes com história de queimaduras há mais de seis meses. Resultados: Após a coleta, observou-se predomínio do gênero masculino, com queimaduras de 3º grau, decorrentes de agentes inflamáveis. Quanto à avaliação de amplitude de movimento, verificou-se que o ombro e o joelho foram as articulações mais comprometidas. E quanto às atividades funcionais, as tarefas mais acometidas foram vestir parte superior e arrumar-se. Conclusões: Considerando-se a relevância desta pesquisa e a amostra reduzida por se tratar de um estudo piloto, sugere-se que sejam realizados novos estudos com um quantitativo maior de pacientes, a fim de que possa haver resultados mais consistentes acerca desta abordagem.


Objective: To evaluate the range of motion of individuals with burn sequelae and interference in functional capacity. Method: This was a cross-sectional, descriptive research, with the sample selected by convenience in the field, consisting of a pilot study. We used the Sanny fleximeter to evaluate the range of motion and the Functional Independence Measure for assessing the functional capacity of the burned patient, following an evaluation protocol made by the researchers themselves. This study was conducted at the Health Center, including patients with a history of burns for more than six months. Results: There was a predominance of males, with burns of 3nd degree, due to flammable agents. Limitation observed in several joints, with a predominance of elbow and ankle, reflecting directly on the functional capability shown by these individuals. The functional activities more affected were dress up and pack up. Conclusions: Considering the relevance of this research and the reduced sample because it is a pilot study, it is suggested that further studies be conducted with a larger number of patients, so that there may be more consistent results about this approach.


Objetivo: El objetivo de esta investigación fue evaluar el rango de movimiento de las personas con secuelas de quemaduras y la interferencia en la capacidad funcional. Método: Esta investigación fue transversal, descriptivo y de campo, y la muestra seleccionada por conveniencia, que consiste en un estudio piloto. Se utilizó el flexímetro Sanny para evaluar la amplitud de movimiento y la medida de la independencia funcional para evaluar la capacidad funcional del paciente quemado, siguiendo un protocolo de evaluación realizado por los propios investigadores. Este estudio se realizó en el Centro derehabilitación, incluyendo pacientes con antecedentes de quemaduras durante más de seis meses. Resultados: Después, hubo un predominio del sexo masculino, con quemaduras de 3er grado, que resulta de agentes inflamables. En cuanto a la gama de evaluación de movimiento, se encontró que las articulaciones del hombro y de la rodilla eran los más afectados. ¿Qué pasa con las actividades funcionales, las tareas más afectados fueron el uso de top y aseo personal. Conclusiones: Teniendo en cuenta la relevancia de esta investigación y la muestra reduce porque se trata de un estudio piloto, se sugiere que se realicen más estudios con una mayor cantidad de pacientes, por lo que puede haber resultados más consistentes en este enfoque.


Subject(s)
Humans , Burns/complications , Range of Motion, Articular , Contracture , Hip/physiopathology , Knee/physiopathology , Epidemiology, Descriptive , Cross-Sectional Studies
4.
Clinics ; 71(8): 425-429, Aug. 2016. tab, graf
Article in English | LILACS | ID: lil-794626

ABSTRACT

OBJECTIVES: Anterior cruciate ligament injury leads to adaptive responses to maintain postural control. However, there is no consensus regarding whether leg dominance also affects postural control in athletes with anterior cruciate ligament injury. The purpose of this study was to evaluate dynamic and static postural control among athletes with and without anterior cruciate ligament injury to the dominant leg. METHODS: Twenty-eight athletes, twenty-one males and seven females aged 15-45 years, were allocated to one of two groups: the anterior cruciate ligament injury group (26±3 years) or the control group without anterior cruciate ligament injury (25±6.5 years). All subjects performed one legged stance tests under eyes open and eyes closed conditions and squat and kick movement tests using a postural control protocol (AccuSwayPlus force platform, Massachusetts). The center of pressure displacement and speed were measured by the force platform. In addition, the distance traveled on the single-leg hop test was assessed as an objective measure of function. RESULTS: Significantly greater mediolateral sway was found under the eyes closed condition (p=0.04) and during squat movement (p=0.01) in the anterior cruciate ligament injury group than in the control group. Analysis of the single-leg hop test results showed no difference between the groups (p=0.73). CONCLUSION: Athletes with anterior cruciate ligament injury had greater mediolateral displacement of the center of pressure toward the dominant leg under the eyes closed condition and during squat movement compared to control athletes.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Young Adult , Anterior Cruciate Ligament Injuries/physiopathology , Athletes , Functional Laterality , Leg/physiopathology , Postural Balance/physiology , Anterior Cruciate Ligament/physiopathology , Case-Control Studies , Cross-Sectional Studies , Joint Instability/physiopathology , Knee Joint/physiopathology , Knee/physiopathology , Movement/physiology , Range of Motion, Articular/physiology , Statistics, Nonparametric
5.
Arq. neuropsiquiatr ; 74(4): 280-286, Apr. 2016. tab, graf
Article in English | LILACS | ID: lil-779811

ABSTRACT

ABSTRACT HTLV-1-associated myelopathy is a progressive disabling disease associated with gait abnormalities. Objective To identify and quantify the main muscles affected by weakness and spasticity, their impact on gait, functional capacity and on quality of life of HTLV-1-associated myelopathy patients. Method We evaluated lower limbs muscular strength according to the Medical Research Council scale, spasticity according to the modified Ashworth scale, daily activities according to the Barthel Index and quality of life according to the Short-Form Health Survey-36 of 26 HTLV-1-associated myelopathy patients. Results The muscles most affected by weakness included the dorsal flexors and knee flexors. Spasticity predominated in the hip adductor muscles and in plantar flexors. Assistance for locomotion, minimal dependence in daily activities, limitations in functional capacity and physical aspects were the most common findings. Conclusion The impairment of gait, functional dependence and quality of life were predominantly a consequence of intense muscle weakness in HTLV-1-associated myelopathy patients.


RESUMO Mielopatia associada ao HTLV-1 é uma doença inflamatória, incapacitante e progressiva que acomete o sistema nervoso central. Objetivo Identificar e quantificar os principais músculos comprometidos pela fraqueza e espasticidade, o impacto na capacidade funcional e na qualidade de vida dos pacientes com mielopatia associada ao HTLV-1. Método Força muscular ( Medical Research Council), espasticidade (escala Ashworth modificada), atividades de vida diária (Índice de Barthel) e qualidade de vida ( Short-Form Health Survey-36) foram avaliados em 26 pacientes . Resultados Os principais músculos comprometidos pela fraqueza incluíram os flexores dorsais e flexores do joelho. A espasticidade predominou nos músculos adutores do quadril e nos flexores plantares. Assistência para locomoção, dependência mínima nas atividades diárias, limitações na capacidade funcional e os aspectos físicos representaram os achados mais frequentes. Conclusão Dificuldade de deambulação, dependência funcional e prejuízo na qualidade de vida foram as principais consequências da intensa fraqueza muscular nos pacientes com mielopatia associada ao HTLV-1.


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Gait Disorders, Neurologic/physiopathology , Muscle Weakness/physiopathology , Paraparesis, Tropical Spastic/physiopathology , Quality of Life , Walking/physiology , Activities of Daily Living , Knee/physiopathology , Muscle Spasticity/physiopathology , Muscle Tonus/physiology , Prospective Studies , Statistics, Nonparametric , Time Factors , Wheelchairs
6.
Yonsei Medical Journal ; : 217-224, 2016.
Article in English | WPRIM | ID: wpr-220779

ABSTRACT

PURPOSE: This study investigated the correlation between isometric muscle strength, gross motor function, and gait parameters in patients with spastic cerebral palsy and to find which muscle groups play an important role for gait pattern in a flexed knee gait. MATERIALS AND METHODS: Twenty-four ambulatory patients (mean age, 10.0 years) with spastic cerebral palsy who were scheduled for single event multilevel surgery, including distal hamstring lengthening, were included. Preoperatively, peak isometric muscle strength was measured for the hip flexor, hip extensor, knee flexor, and knee extensor muscle groups using a handheld dynamometer, and three-dimensional (3D) gait analysis and gross motor function measure (GMFM) scoring were also performed. Correlations between peak isometric strength and GMFM, gait kinematics, and gait kinetics were analyzed. RESULTS: Peak isometric muscle strength of all muscle groups was not related to the GMFM score and the gross motor function classification system level. Peak isometric strength of the hip extensor and knee extensor was significantly correlated with the mean pelvic tilt (r=-0.588, p=0.003 and r=-0.436, p=0.033) and maximum pelvic obliquity (r=-0.450, p=0.031 and r=-0.419, p=0.041). There were significant correlations between peak isometric strength of the knee extensor and peak knee extensor moment in early stance (r=0.467, p=0.021) and in terminal stance (r=0.416, p=0.043). CONCLUSION: There is no correlation between muscle strength and gross motor function. However, this study showed that muscle strength, especially of the extensor muscle group of the hip and knee joints, might play a critical role in gait by stabilizing pelvic motion and decreasing energy consumption in a flexed knee gait.


Subject(s)
Female , Humans , Male , Biomechanical Phenomena , Cerebral Palsy/physiopathology , Gait/physiology , Isometric Contraction/physiology , Knee/physiopathology , Knee Joint/surgery , Muscle Spasticity/etiology , Muscle Strength/physiology , Muscle Strength Dynamometer , Muscle, Skeletal/physiopathology , Pelvis , Postural Balance/physiology , Tenotomy
7.
J. bras. pneumol ; 41(4): 305-312, July-Aug. 2015. tab, ilus
Article in English | LILACS | ID: lil-759335

ABSTRACT

AbstractObjective: To compare equations for predicting peak quadriceps femoris (QF) muscle force; to determine the agreement among the equations in identifying QF muscle weakness in COPD patients; and to assess the differences in characteristics among the groups of patients classified as having or not having QF muscle weakness by each equation.Methods: Fifty-six COPD patients underwent assessment of peak QF muscle force by dynamometry (maximal voluntary isometric contraction of knee extension). Predicted values were calculated with three equations: an age-height-weight-gender equation (Eq-AHWG); an age-weight-gender equation (Eq-AWG); and an age-fat-free mass-gender equation (Eq-AFFMG).Results: Comparison of the percentage of predicted values obtained with the three equations showed that the Eq-AHWG gave higher values than did the Eq-AWG and Eq-AFFMG, with no difference between the last two. The Eq-AHWG showed moderate agreement with the Eq-AWG and Eq-AFFMG, whereas the last two also showed moderate, albeit lower, agreement with each other. In the sample as a whole, QF muscle weakness (< 80% of predicted) was identified by the Eq-AHWG, Eq-AWG, and Eq-AFFMG in 59%, 68%, and 70% of the patients, respectively (p > 0.05). Age, fat-free mass, and body mass index are characteristics that differentiate between patients with and without QF muscle weakness.Conclusions: The three equations were statistically equivalent in classifying COPD patients as having or not having QF muscle weakness. However, the Eq-AHWG gave higher peak force values than did the Eq-AWG and the Eq-AFFMG, as well as showing greater agreement with the other equations.


ResumoObjetivo:Comparar diferentes fórmulas de predição do pico de força muscular do quadríceps femoral (QF); investigar a concordância entre elas para identificar fraqueza muscular de QF em pacientes com DPOC; e verificar as diferenças nas características nos grupos de pacientes classificados com presença ou ausência dessa fraqueza de acordo com cada fórmula.Métodos: Cinquenta e seis pacientes com DPOC foram avaliados quanto ao pico de força muscular do QF por dinamometria (contração isométrica voluntária máxima de extensão de joelho). Os valores preditos foram calculados com três fórmulas: uma fórmula composta por idade-altura-peso-gênero (F-IAPG); uma por idade-peso-gênero (F-IPG); e uma por idade-massa magra-gênero (F-IMMG).Resultados: A comparação da porcentagem do predito obtida pelas fórmulas mostrou a F-IAPG com maiores valores do que os valores de F-IPG e F-IMMG, sem diferença entre as duas últimas. A F-IAPG apresentou concordância moderada com F-IPG e F-IMMG, enquanto essas últimas também apresentaram concordância moderada, mas menor, entre si. Do total de pacientes, a fraqueza muscular de QF (< 80% do predito) foi identificada por F-IAPG, F-IPG e F-IMMG em 59%, 68% e 70% dos pacientes, respectivamente (p > 0,05). Idade, massa magra e índice de massa corpórea são características que diferenciam pacientes com e sem fraqueza muscular de QF.Conclusões: As três fórmulas foram estatisticamente equivalentes para classificar pacientes com DPOC como portadores ou não de fraqueza muscular de QF. Entretanto, a F-IAPG apresentou maiores valores de pico de força do que F-IPG e F-IMMG, assim como maior concordância com as outras fórmulas.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Algorithms , Muscle Strength/physiology , Muscle Weakness/diagnosis , Pulmonary Disease, Chronic Obstructive/physiopathology , Quadriceps Muscle/physiopathology , Adiposity , Age Factors , Body Height , Body Mass Index , Body Weight , Cross-Sectional Studies , Health Services Needs and Demand , Isometric Contraction/physiology , Knee/physiopathology , Muscle Strength Dynamometer/trends , Predictive Value of Tests , Respiratory Function Tests , Sex Factors
8.
Rev. chil. ortop. traumatol ; 56(2): 13-17, mayo-ago.2015. ilus, tab, graf
Article in Spanish | LILACS | ID: lil-795837

ABSTRACT

Determinar qué porcentaje de una población sin dolor anterior de rodilla tiene un test de Zohlen positivo, además determinar el ángulo Q de esta población y buscar si existe alguna relación entre la positividad del test de Zohlen y alteraciones en el ángulo Q. Material y método: Estudio descriptivo-prospectivo observacional. Aplicación del test de Zohlen y medición del ángulo Q. La población se dividió en 2 grupos: test de Zohlen positivo y test de Zohlen negativo. Cuantificación y comparación de medias del ángulo Q en los dos grupos. Resultados: 90 sujetos evaluados, promedio de edad 20,18 años (18-40). Veinte sujetos (22,2 por ciento) con test de Zohlen positivo. Ángulo Q promedio en los sujetos con test de Zohlen negativo: 14,95°; ángulo Q promedio en los sujetos con test de Zohlen positivo: 16,9° (p < 0,05). Ángulo Q promedio en hombres con test de Zohlen negativo 13,4°; ángulo Q promedio en hombres con test de Zohlen positivo: 16° (p < 0,05). Ángulo Q promedio en mujeres con test de Zohlen negativo: 16,5°; ángulo Q promedio en mujeres con test de Zohlen positivo: 18°, sin diferencias estadísticamente significativas entre ambos grupos. Conclusiones: El test de Zohlen tiene una correlación positiva con el ángulo Q en sujetos de sexo masculino. Dada la correlación entre un ángulo Q alterado y la presencia de dolor anterior de rodilla, en los pacientes que presentan un test de Zohlen positivo sin haber consultado por dolor anterior de rodilla, la prevención primaria de dolor anterior de rodilla puede ser de utilidad...


To determine the percentage of a population without anterior knee pain with a positive Zohlen test, and also to determine the Q angle of this population and to determine if there is any relationship between the Zohlen test and Q angle anomalies. Methods:A prospective observational study was conducted in which Zohlen¿s test was applied and the Q angle was measured. The population was divided into 2 groups: Zohlen¿s positive and Zohlen¿s negative. Q angle was compared in the 2 groups. Results: The study included 90 subjects, with a mean age 20.18 years (18-40), of whom 20 subjects (22.2 percent) had positive Zohlen¿s test. The mean Q angle in subjects with negative Zohlen¿s test was 14.95°, and the mean Q angle in subjects with positive Zohlen¿s test was 16,9° (p<.05). The mean Q angle in men with negative Zohlen¿s test was 13.4°, and the mean Q angle in men with positive Zohlen¿s test was 16° (p < .05). The mean Q angle in women with negative Zohlen¿s test was 16.5°, with a mean Q angle of 18° in women with positive Zohlen¿s test, with no statistically significant differences found between groups. Conclusions: Zohlen¿s test has a positive correlation with the Q angle in male subjects. Given the correlation between the Q angle and the presence of anterior knee pain in patients who have a positive test without symptoms, primary prevention of anterior knee pain can be achieved...


Subject(s)
Humans , Male , Adolescent , Adult , Female , Young Adult , Knee/physiology , Knee/physiopathology , Patellofemoral Pain Syndrome/diagnosis , Patellofemoral Joint/physiology , Patellofemoral Joint/physiopathology , Arthralgia/diagnosis , Observational Study , Prospective Studies
9.
Yonsei Medical Journal ; : 1703-1713, 2015.
Article in English | WPRIM | ID: wpr-70399

ABSTRACT

PURPOSE: The purpose of our study was to investigate the effect of gait training with rhythmic auditory stimulation (RAS) on both kinematic and temporospatial gait patterns in patients with hemiplegia. MATERIALS AND METHODS: Eighteen hemiplegic patients diagnosed with either cerebral palsy or stroke participated in this study. All participants underwent the 4-week gait training with RAS. The treatment was performed for 30 minutes per each session, three sessions per week. RAS was provided with rhythmic beats using a chord progression on a keyboard. Kinematic and temporospatial data were collected and analyzed using a three-dimensional motion analysis system. RESULTS: Gait training with RAS significantly improved both proximal and distal joint kinematic patterns in hip adduction, knee flexion, and ankle plantar flexion, enhancing the gait deviation index (GDI) as well as ameliorating temporal asymmetry of the stance and swing phases in patients with hemiplegia. Stroke patients with previous walking experience demonstrated significant kinematic improvement in knee flexion in mid-swing and ankle dorsiflexion in terminal stance. Among stroke patients, subacute patients showed a significantly increased GDI score compared with chronic patients. In addition, household ambulators showed a significant effect on reducing anterior tilt of the pelvis with an enhanced GDI score, while community ambulators significantly increased knee flexion in mid-swing phase and ankle dorsiflexion in terminal stance phase. CONCLUSION: Gait training with RAS has beneficial effects on both kinematic and temporospatial patterns in patients with hemiplegia, providing not only clinical implications of locomotor rehabilitation with goal-oriented external feedback using RAS but also differential effects according to ambulatory function.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Acoustic Stimulation/methods , Ankle Joint/physiopathology , Biomechanical Phenomena , Cerebral Palsy/diagnosis , Foot Joints/physiopathology , Gait , Gait Disorders, Neurologic/etiology , Hemiplegia , Knee/physiopathology , Knee Joint/physiopathology , Stroke/diagnosis
10.
Journal of Korean Academy of Nursing ; : 823-833, 2015.
Article in Korean | WPRIM | ID: wpr-9455

ABSTRACT

PURPOSE: The purpose of the study was to investigate the effects of the Thera-Band exercise program following total knee arthroplasty. METHODS: The research design for this study was a nonequivalent control group non-synchronized design. Participants were 30 patients for the experimental group and 30 patients for the control group. The experimental group participated in the Thera- Band exercise program in addition to conventional CPM (continuous passive motion) exercise. The control group received conventional CPM exercise only. Outcome measures were pain, knee flexion range of motion, CRP, and psychological parameters (self-efficacy and fear of falling). Data were analyzed using chi2-test, Fisher's exact test, t-test, and repeated measure ANOVA with SPSS/PC version 21.0. RESULTS: There were significant improvement in self-efficacy, and decreases in pain, and fear of falling in the experimental group compared to the control group. However, no significant differences were found between the two groups for CRP and knee flexion ROM. CONCLUSION: The Thera-Band exercise program gave an additional benefit over the conventional CPM exercise for patients following total knee arthroplasty, and is recommended for use as an effective nursing intervention for patients after total knee arthroplasty.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Accidental Falls , Arthroplasty, Replacement, Knee , C-Reactive Protein/analysis , Exercise Therapy , Knee/physiopathology , Knee Injuries/psychology , Pain/pathology , Pain Management , Range of Motion, Articular , Self Efficacy , Surveys and Questionnaires
11.
Fisioter. pesqui ; 21(3): 209-216, Jul-Sep/2014. tab, graf
Article in English | LILACS | ID: lil-728742

ABSTRACT

The turnout, primary gesture in classical ballet, refers the 180º of the feet. The lateral rotation provides the greatest amount of degrees necessary to perform the position perfectly. If performed improperly, it can generate problems, specialy in the knees, causing pain. The aim of this study was to evaluate the factors that influence the implementation of turnout in adolescents ballet dancers with knee pain and to compare them to the dancers without pain. Twenty three (23) ballet dancers with knee pain and 26 ballet dancers without pain were evaluated for range of motion of external rotation of the hip, muscle strength, femoral neck anteversion and static and dynamic turnout. The angles were measured with a manual goniometer, and the strength of the abductor muscle groups, external rotators and hip extensors with isometric dynamometer. The analysis was performed using ANOVA and Mann-Whitney. Range of motion of external rotation of the hip, femoral neck anteversion and muscle strength were similar between groups. The dynamic turnout was lower in ballet dancers with knee pain (p=0.02) and ballerinas with angular deficits above 10% over the static group had lower turnout under the bilateral extensor muscle group (p=0.04 and 0.03, right left) and right abductor (p=0.03). Although anatomical factors can influence the lateral rotation of the turnout, the angle decreased dynamic turnout was related to the group of dancers with pain. This suggests that training based on proximal awareness of movement can prevent and minimize burdens on the knees of classical dancers teens.


El turnout, principal gesto del ballet clásico, se refiere a la posición de 180º entre los pies. La rotación lateral de la cadera proporciona una mayor cantidad de grados necesarios para realizar la posición perfectamente. Si se realiza de forma inadecuada, puede generar compensaciones, preferentemente en las rodillas, generando dolor. El objetivo de este estudio fue evaluar los factores que influyen en la ejecución del turnout en bailarinas clásicas adolescentes con dolor en las rodillas y comparar las bailarinas y sin dolor. Se evaluaron a 23 bailarinas con dolor y 26 bailarinas sin dolor en cuanto al rango de movimiento de rotación lateral de la cadera, la fuerza muscular, a la anteversión del cuello femoral y al turnout estático y dinámico. Los ángulos fueron medidos con un goniómetro manual, y la fuerza de los grupos musculares abductores, rotadores externos y extensores de la cadera con dinamómetro isométrico. El análisis se realizó por medio del ANOVA y Mann-Whitney. El rango de movimiento, la anteversión del cuello femoral y la fuerza del músculo fueron similares entre los grupos. El turnout dinámico fue menor en el grupo de bailarinas con dolor (p=0,02), y las bailarinas con déficits angulares superiores a 10% en relación al turnout estático presentaron menor fuerza del grupo muscular de los extensores bilaterales (p=0,04 y 0,03, derecha e izquierda) y abiductores derecho (p=0,03). Aunque los factores anatómicos pueden influir en la rotación lateral del turnout, la disminución del ángulo del turnout dinámico se relacionó con el grupo de bailarinas con dolor. Tal hecho sugiere que el entrenamiento basado en la conciencia proximal del movimiento puede prevenir y minimizar las sobrecargas en las rodillas de bailarinas clásicas adolescentes.


O turnout, gesto principal do balé clássico, refere-se à posição de 180º entre os pés. A rotação lateral do quadril fornece a maior quantidade de graus necessários para realizar a posição com perfeição. Se executada de forma inadequada, pode gerar compensações, preferencialmente nos joelhos, ocasionando dor. O objetivo deste estudo foi avaliar fatores que influenciam na execução do turnout em bailarinas clássicas adolescentes com dor nos joelhos e comparar a bailarinas sem dor. Foram avaliadas 23 bailarinas com dor e 26 bailarinas sem dor quanto à amplitude de movimento de rotação lateral do quadril, força muscular, à anteversão do colo femoral e ao turnout estático e dinâmico. Os ângulos foram mensurados com goniômetro manual, e a força dos grupos musculares abdutores, rotadores laterais e extensores do quadril com dinamômetro isométrico. A análise foi feita por meio do ANOVA e Mann-Whitney. A amplitude de movimento, a anteversão do colo femoral e a força muscular foram semelhantes entre os grupos. O turnout dinâmico foi menor no grupo de bailarinas com dor (p=0,02), e bailarinas com déficits angulares acima 10% em relação ao turnout estático apresentaram menor força do grupo muscular dos extensores bilateral (p=0,04 e 0,03, direita e esquerda) e abdutores direito (p=0,03). Embora fatores anatômicos possam influenciar na rotação lateral do turnout, a diminuição angular do turnout dinâmico esteve mais relacionada ao grupo de bailarinas com dor. Tal fato sugere que o treinamento baseado na conscientização proximal do movimento pode prevenir e minimizar as sobrecargas nos joelhos de bailarinas clássicas adolescentes.


Subject(s)
Humans , Female , Adolescent , Dancing/injuries , Lower Extremity/physiopathology , Lower Extremity/injuries , Knee/physiopathology , Hip Injuries/complications , Hip Injuries/physiopathology , Muscle Strength , Pain , Knee Injuries/complications , Femur Neck/physiopathology , Femur Neck/injuries , Range of Motion, Articular
12.
Fisioter. pesqui ; 20(2): 130-135, abr.-jun. 2013. graf, tab
Article in Portuguese | LILACS | ID: lil-683202

ABSTRACT

Este estudo visou determinar a influência da Síndrome da Dor Patelofemoral (SDPF) sobre o pico de torque e trabalho da musculatura flexora e extensora do joelho, além de avaliar a dor e funcionalidade de sujeitos com a disfunção. Participaram 52 sujeitos do gênero feminino, 23 com SDPF e 29 clinicamente saudáveis similares em idade, estatura e massa corporal. A avaliação isocinética foi realizada no modo concêntrico para os flexores e extensores do joelho nas velocidades de 60 e 180°/s. Também foi aplicada a Escala Visual Numérica antes e após cada velocidade do teste isocinético e o questionário de Kujala. Os dados foram analisados pela estatística descritiva e inferencial (testes U de Mann-Whitney, Wilcoxon e t independente) com nível de significância de α=0,05. O Grupo com Síndrome da Dor Patelofemoral (GSDPF) apresentou menor pontuação (p=0,01) no questionário de Kujala (75,7±12,3 pontos) em relação ao Grupo Controle (GC) (100±0,0 pontos), além de menor pico de torque, tanto em 60 como 180°/s, dos flexores (0,82±0,24 Nm/kg; 0,51±0,22 Nm/kg) e extensores (1,85±0,48 Nm/kg; 1,13±0,44 Nm/kg) do joelho, bem como menor trabalho total dos extensores do joelho a 180°/s (6,46±2,54 J/kg) e 60°/s (9,42±3,27 J/kg). Além disso, foi observado aumento da dor do GSDPF após a avaliação isocinética a 180°/s (0,9 cm) e 60°/s (2,3 cm). Os resultados evidenciaram que sujeitos com SDPF possuem menor capacidade funcional e menor pico de torque e trabalho dos flexores e extensores do joelho, sugerindo que o fortalecimento desta musculatura deve ser considerado na reabilitação destes sujeitos...


The aim of this study was to determine the influence of Patellofemoral Pain Syndrome (PFPS) on peak torque and work in knee flexor and extensor muscles. In addition to evaluate pain and function of subjects with the disfunction. Fifty two females subjects, 23 with diagnosis of PFPS and 29 control subjects, similar for age, height and body mass, participated in this study. The isokinetic evaluation was performed in concentric mode for knee flexors and extensors at speeds of 60 and 180°/s. In addition, was applied to Visual Numerical Scale before and after each velocity of isokinetic testing and Kujala questionnaire. Data were analyzed by descriptive and inferential statistics (U Mann-Whitney, Wilcoxon and t independent tests) with alpha level at α=0.05. The Patellofemoral Pain Syndrome Group (PFPSG) had lower scores (p=0.01) on Kujala questionnaire (75.7±12.3 points) in relation to Control Group (CG) (100±0.0 points), and lower peak torque of knee flexors (0.82±0.24 Nm/kg; 0.51±0.22 Nm/kg) and extensors (1.85±0.48 Nm/kg; 1.13±0.44 Nm/kg) in 60 and 180°/s and lower total work of knee extensors at 180°/s (6.46±2.54 J/kg) and 60°/s (9.42±3.27 J/kg). In addition, there was exacerbation of pain in PFPSG after the isokinetic evaluation at 180°/s (0.9 cm) and 60°/s (2.3 cm). The results showed that individuals with PFPS have lower functional capacity and lower peak torque and work flexors and knee extensors, suggesting that strengthening these muscles must be considered in the rehabilitation of these subjects...


Este estudio tiene como objetivo determinar la influencia del Síndrome de Dolor Patelofemoral (SDPF) sobre el peak de torque y el trabajo de la musculatura flexora y extensora de la rodilla, además de evaluar el dolor y la funcionalidad de sujetos con esta disfunción. Participaron 52 sujetos de género femenino, 23 con SDPF (GSDPF) y 29 clínicamente saludables (GC) similares en edad, estatura y masa corporal. La evaluación isocinética fue realizada en el modo concéntrico para los flexores y extensores de rodilla en las velocidades de 60 y 180°/s. También fue aplicada la Escala Visual Numérica antes y después de cada velocidad del test isocinético y el Cuestionario de Kujala. Los datos fueron analizados por estadística descriptiva e inferencial (Tests U de Mann-Whitney, Wilcoxon y T independiente) con un nivel de significancia de α=0,05. El GSDPF presentó menor puntuación (p=0,01) en el Cuestionario de Kujala (75,7±12,3 puntos) en relación al GC (100±0,0 puntos), además presentó un menor peak de torque, tanto en 180°/s y 60°/s. Los resultados evidencian que sujetos con SDPF poseen menor capacidad funcional y peak de torque de trabajo de los flexores y extensores de rodilla, sugiriendo que el fortalecimiento de esta musculatura debe ser considerada en la rehabilitación de estos sujetos...


Subject(s)
Humans , Female , Adolescent , Young Adult , Knee/physiopathology , Pain Measurement , Patellofemoral Pain Syndrome/etiology , Torque , Musculoskeletal Pain , Surveys and Questionnaires
13.
Acta ortop. bras ; 21(2): 80-86, mar.-abr. 2013. ilus, tab
Article in Portuguese | LILACS | ID: lil-676847

ABSTRACT

Objetivo: Avaliar a regeneração da cartilagem articular em defeitos osteocondrais do joelho induzidos pelo plasma rico em plaquetas (PRP) autógeno. Métodos: Defeitos osteocondrais produzidos no sulco troclear de ambos os joelhos de dez ovelhas foram preenchidos com PRP autógeno à direita e deixados vazios à esquerda. Avaliação macroscópica e histológica foram efetuadas 12 semanas mais tarde. Os resultados foram avaliados por um escore geral de ambas as avaliações macroscópica e histológica comparativamente entre os lados por meio do teste pareado de Wilcoxon. Resultados: o aspecto macroscópico não foi uniforme entre os animais, nem diferiu entre os joelhos direitos e esquerdos (p=0,03125); em nenhum caso o tecido regenerado se nivelou com a cartilagem normal circundante. Ao exame histológico, cartilagem aparentemente normal não foi detectada em nenhum joelho, mas uma cartilagem pouco diferenciada estava presente em sete joelhos direitos e em três joelhos esquerdos. Tecido fibrocartilaginoso estava presente nos joelhos restantes, com diferença significante no escore geral entre os joelhos direitos e esquerdos (p=0,0313). Conclusão: o PRP como usado neste estudo tem propriedades reparativas da cartilagem articular no joelho de ovelhas, principalmente por estimular a formação de tecido fibrocartilaginoso. Trabalho Experimental.


Objective: To assess the regeneration of osteochondral defects in the joint cartilage of the knee induced by autologous platelet-rich plasma (PRP). methods: osteochondral defects produced in the trochlear groove of both knees of ten sheep; defects of the right knees were filled with autologous PRP and the left knees were left unfilled. macroscopic and microscopic evaluation was carried out 12 week later. the results were evaluated by the total score of both macroscopic and microscopic evaluations comparing the two sides through the wilcoxon paired test. Results: macroscopic appearance was not uniform among animals, nor was it different between the right and left knees (p=0.3125), and in no case the regenerated tissue was equal to the normal surrounding cartilage. At histological examination, apparently normal cartilage was not detected in any knee, but a poorly differentiated cartilage was present in 7 right knees, compared to 3 left knees. Fibrocartilaginous tissue was present in most of the remaining knees, with a significant difference in the overall score between right and left knees (p=0.0313). conclusion: the pRp as used in this study has reparative properties of the joint cartilage of sheep knees, mostly by stimulating the formation of a fibrocartilaginous tissue. Laboratory Investigation.


Subject(s)
Animals , Female , Gels , Histology, Comparative , Knee/physiopathology , Osteochondritis/surgery , Osteochondritis/rehabilitation , Plasma , Sheep , Trochlear Nerve Injuries
14.
Radiol. bras ; 46(1): 59-60, jan.-fev. 2013. ilus
Article in Portuguese | LILACS | ID: lil-666113

ABSTRACT

Dysplasia epiphysealis hemimelica is a rare benign disease (incidence 1:1,000,000), characterized by an osteochondral overgrowth affecting one or more epiphyses. Generally, the age of onset is between two and 14 years. The characteristic imaging findings are sufficient for the diagnosis. Surgical excision of the lesion is only indicated in cases where a functional limitation is present.


A displasia epifisária hemimélica é uma doença benigna rara (incidência de 1:1.000.000), caracterizada por um crescimento osteocondral decorrente de uma ou mais epífises. Em geral a idade de início é entre 2 e 14 anos. Os achados característicos dos exames de imagem são suficientes para o diagnóstico. A excisão cirúrgica da lesão só é indicada caso haja limitação funcional.


Subject(s)
Humans , Male , Child, Preschool , Epiphyses/physiopathology , Knee/physiopathology , Knee , Osteochondrodysplasias/surgery , Osteochondrodysplasias/diagnosis , Tomography, X-Ray Computed
15.
Rev. bras. ortop ; 47(6): 719-723, 2012. ilus, tab
Article in Portuguese | LILACS | ID: lil-666215

ABSTRACT

OBJETIVOS: O propósito do presente estudo é revisar aspectos epidemiológicos das rupturas tendinosas do aparelho extensor do joelho em hospital de nível I. MÉTODOS: Analisamos, retrospectivamente, 76 lesões do mecanismo extensor do joelho, tratadas cirurgicamente no Hospital Municipal Miguel Couto, no período de março de 2004 a março de 2011. Levamos em consideração idade, sexo, mecanismo de trauma, classificação anatômica da lesão, lado acometido, comorbidades e lesões associadas. RESULTADOS: Dos pacientes estudados, 68 eram do sexo masculino, com idade média de 36 anos. Quanto ao mecanismo de trauma, 62 foram por trauma direto, 21 casos foram do lado direito, oito apresentavam comorbidades e quatro tiveram lesões associadas. CONCLUSÕES: A maioria dos pacientes foi do sexo masculino, na faixa etária economicamente ativa (jovens), e vítima de trauma direto, sendo as rupturas do ligamento patelar as lesões mais comuns. Lesões associadas são raras, e as comorbidades foram pouco frequentes em nossa casuística.


OBJECTIVES: The purpose of the present study was to review the epidemiological aspects of tendon ruptures of the knee extensor apparatus at a level 1 hospital. METHODS: We retrospectively ana lyzed 76 lesions of the knee extensor apparatus that were treated surgically at the Miguel Couto Municipal Hospital between March 2004 and March 2011. We took into consideration age, sex, trauma mechanism, anatomical classification of the lesion, affected side, comorbidities and associated lesions. RESULTS: Among the patients studied, 68 were male and the mean age was 36 years. Regarding the trauma mechanism, 62 lesions occurred due to direct trauma; the right side was affected in 21 cases; eight presented comor bidities and four presented associated lesions. CONCLUSION: The majority of the patients were male, at an economically active age (young people), and were victims of direct trauma. Ruptures of the patellar ligament were the most frequent lesions. Associated lesions were rare and comorbidities were infrequent in our sample.


Subject(s)
Humans , Male , Female , Child , Adolescent , Young Adult , Middle Aged , Knee/physiopathology , Rupture/epidemiology , Knee Injuries/epidemiology
16.
Gulf Medical University: Proceedings. 2012; (5-6 November): 153-158
in English | IMEMR | ID: emr-142857

ABSTRACT

To identify and compare the [two joint muscles] mechanics of spastic cerebral palsies and to manipulate the [two joint muscles] mechanics to improve gait quality in spastic CPs. Nine Spastic CPs, [two males and seven females, of mean age 4.9 years], were studied, following the categorical selection criteria. The therapeutic regimen was reinforced by, [specific muscle reeducation techniques] focusing to inhibit the abnormal synergism. The spastics had higher stiffness due to the primary impairments [muscle tone/ movement patterns, distribution, balance etc.], differences in the landing angles of feet due to secondary impairments [ROM, joint alignment, force production, etc.] and higher energy requirements. Interventions to enhance outcomes were positively correlated. The potential determinants of motor change in two joint muscles could assist in the functional performance with regard to gait and posture. Biochemical studies on energy requirements in CPs are recommended


Subject(s)
Humans , Male , Female , Gait Disorders, Neurologic/etiology , Muscle Spasticity , Muscle, Skeletal/physiopathology , Range of Motion, Articular , Knee/physiopathology
17.
Rev. bras. ortop ; 46(1): 14-17, 2011.
Article in Portuguese | LILACS | ID: lil-596368

ABSTRACT

Avanços no conhecimento da fisiopatologia da dor em doentes com osteoartrose de joelho apontam para a participação do sistema nervoso central como fonte mantenedora e amplificadora do quadro álgico refratário aos tratamentos ortopédico e reumatológico habituais. Inicialmente, a hipersensibilidade é observada apenas no local afetado. Entretanto, quando a dor torna-se refratária, mecanismos de sensibilização central e periférica passam a contribuir para a manutenção e amplificação dos quadros dolorosos, independentes do processo periférico que a originou. Neste estágio, mesmo a remoção do agente etiológico pode não mais ser suficiente para o alívio dos sintomas dolorosos. Faz-se necessário então considerar que outros fatores, distantes da própria articulação acometida, podem ser os responsáveis pelos sintomas dolorosos e incapacitantes nestes doentes. No momento não há cura conhecida para a osteoartrose e o objetivo do tratamento é a melhora da dor, da função e da qualidade de vida relacionada à saúde, minimizando, sempre que possível, a toxicidade terapêutica. Diante das evidências emergentes sugerindo o papel do sistema nervoso central na fisiopatologia da dor em doentes com artrose de joelho, os alvos terapêuticos devem contemplar as estruturas do sistema nervoso central, ao invés do tratamento apenas local com analgésicos comuns, antiinflamatórios e medidas não farmacológicas. Assim, modalidades de modulação da medula espinal e do córtex cerebral, incluindo o uso de antidepressivos, podem ter o seu papel no manejo desses doentes.


Advances in knowledge regarding the pathophysiology of pain among patients with knee osteoarthritis suggest that the central nervous system is involved as a source that maintains and amplifies the painful condition such that it is refractory to conventional orthopedic and rheumatological treatment. Initially, hyperalgesia is observed only at the affected site. However, when the pain becomes refractory, peripheral and central sensitization mechanisms contribute towards maintaining and amplifying the painful conditions, regardless of the peripheral process that originated the pain. At this stage, even removal of the etiological agent may no longer be enough to relieve the painful symptoms. It then becomes necessary to envisage that other factors, distant from the affected joint, may be responsible for the disabling painful condition in such patients. At present, osteoarthrosis does not have any known cure, and the aim of treatment is to lessen the pain while improving function and health -related quality of life, and whenever possible, to minimize the toxicity of the therapy. In the light of emerging evidence suggesting that the central nervous system has a role in the physiopathology of pain in patients with knee arthrosis, the central nervous system should be taken into consideration as a therapeutic target, instead of only administering local treatment using ordinary analgesics, antiinflammatory drugs and non-pharmacological measures. Thus, methods that modulate the spinal cord and cerebral cortex, including the use of antidepressants, may have a role in managing these patients.


Subject(s)
Joint Diseases , Knee/physiopathology , Pain/drug therapy
18.
Indian J Pediatr ; 2010 Feb; 77(2): 196-197
Article in English | IMSEAR | ID: sea-142500

ABSTRACT

A six-day-old girl, born to normal non-consanguineous parents presented with mask like facies with a small mouth giving a ‘whistling’ appearance. Other dysmorphic features include deep set eyes, broad nasal bridge, long philtrum and ‘H’ shaped cutaneous dimple on the chin. There was congenital windmill vane hand position and severe talipes equinovarus deformity. The above features are characteristic of Freeman-Sheldon syndrome also known as Whistling Face syndrome. Ultrasound scanning during 8th month of the pregnancy showed the fetus to have facial abnormality and bilateral clenched hand and talipes with extension contractures of knees. Provisional diagnosis of FSS was made which was confirmed after the birth. Thus all cases of Arthrogryposis during prenatal scan should be carefully looked for the facial abnormality in the fetus.


Subject(s)
Arthrogryposis/diagnosis , Arthrogryposis/genetics , Arthrogryposis/physiopathology , Cytoskeletal Proteins/genetics , Facies , Female , Foot Deformities/complications , Foot Deformities/diagnosis , Humans , Infant, Newborn , Knee/physiopathology , Pregnancy , Prenatal Diagnosis , Syndrome
19.
Clinics ; 65(1): 29-34, 2010. tab
Article in English | LILACS | ID: lil-538604

ABSTRACT

Objectives: The efficacy of combined lumbar plexus-sciatic nerve blocks was compared to epidural anesthesia in patients undergoing total knee surgery. Patients and methods: The study included 80 American Society of Anesthesiologists (ASA) Physical Status I-III patients (age range 18 to 65) undergoing knee surgery. The patients were randomly divided into one of two groups. Epidural anesthesia was performed in the epidural anesthesia (EA) group (n=40), and the lumbar plexus and sciatic nerves were blockedin the lumbar plexus-sciatic nerve blocks (LPSB) group (n=40). For each patient, onset of sensory and motor block, degree of motor block, sign of sensory block in the contralateral lower limb for the lumbar plexus-sciatic nerve blocks group, success in providing adequate anesthesia, hemodynamic changes, time of first analgesic request, and patient and surgeon satisfaction with the anesthetic technique were recorded. Results: One patient in the epidural anesthesia group and three patients in the lumbar plexus-sciatic nerve blocks group required general anesthesia due to failed block. There were no significant differences between the two groups regarding the success of providing adequate anesthesia. Eight patients in the lumbar plexus-sciatic nerve blocks group developed contralateral spread. The onset of sensory-motor block and the time of the first analgesic request were significantly later in the lumbar plexus-sciatic nerve blocks group than in the epidural anesthesia group. Although there were no significant differences regarding patient satisfaction with the anesthetic technique between the two groups, surgeon satisfaction was significantly higher in the lumbar plexus-sciatic nerve blocks group than in the epidural anesthesia group. Conclusion: The lumbar plexus -sciatic nerve blocks provide effective unilateral anesthesia and may offer a beneficial alternative to epidural anesthesia in patients undergoing total knee surgery.


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Anesthesia, Epidural/methods , Knee/surgery , Lumbosacral Plexus , Nerve Block/adverse effects , Sciatic Nerve , Job Satisfaction , Knee/physiopathology , Nerve Block/methods , Patient Satisfaction/statistics & numerical data , Young Adult
20.
Rev. chil. reumatol ; 23(1): 33-41, 2007. tab, graf
Article in Spanish | LILACS | ID: lil-475708

ABSTRACT

We developed a prospective, open study to evaluate the efficacy of chondroitin sulfate in the treatment of kneeosteoarthritis. Methodology: We studied 61 patients with primary knee osteoarthritis. They were given 800mg/day chondroitin 4-and 6- sulfate (Condrosulf, IBSA, Switzerland) for a period of three months. Patients were controlled every 30 days using the Lequesne index and the visual analogue pain scale. Medication was suspended after 90 days and patients were reevaluated 90 days later. Only Paracetamol was allowed as analgesic. Results: After 90 days a significant improvement of45 percent was observed in the Lequesne index, and 59 percent for knee pain. Once medication is suspended, the effect tends to slowly revert, with final study results significantly better than basal levels. Residual effect is better in patients under age 65 and in those with less basal radiological damage. Subjective opinion of both patient and doctor concurs with results. Conclusions: Chondroitin 4-and 6- sulfate is effective for the symptomatic treatment of knee osteoarthritis. Its effect lasts several months after drug suspension.


Subject(s)
Humans , Male , Female , Middle Aged , Mice , Chondroitin , Osteoarthritis, Knee/diagnosis , Knee/physiopathology
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