ABSTRACT
Presence of volatile N-nitrosamines in beer and other alcoholic drinks are well documented in developed countries. Analysis of 120 beer samples of various brands/batches showed positivity for N-nitrosodimethylamine (NDMA) in more than 100 samples. The overall mean of 3.6 ppb of NDMA is higher than those currently found in Western countries. Since N-nitrosamines are proven carcinogens in animals at several sites it is necessary to keep their levels of exposure to as low as possible.
Subject(s)
Beer/analysis , Dimethylnitrosamine/analysis , India , Nitrosamines/analysisABSTRACT
N-nitrosamines - potent carcinogenic, embryopathic, teratogenic and mutagenic agents - hve been detected in baby bottle nipples and pacifiers. Due to children's special vulnerability to the toxic effects of these compounds, some countries have established limits and worked with industries to minimize their levels. However, in several other countries where the problem of high levels still exists, recommendations to minimize exposure are of importance. This article reviews the source as well as the types and levels of N-nitrosamines, nitrosatable amines and nitramines in baby bottle nipples and pacifiers. In addition, the effect of sterilization, migration of these compounds into water, milk, infant formulas, juices and saliva as well as their in vivo formation are discussed
Subject(s)
Humans , Infant, Newborn , Nutritional Support/instrumentation , Infant Care/instrumentation , Nitrosamines/analysis , Food Contamination/analysis , Rubber/chemistry , SterilizationABSTRACT
O artigo aborda a ocorrencia natural de nitratos e nitritos em alimentos e seu uso intencional como conservadores em produtos cárneos curados. Säo discutidos efeitos adversos à saúde atribuídos à ingestäo de nitratos e nitritos, incluindo induçäo de metemoglobinemia e formaçäo de N-nitrosaminas. Säo também apresentados dados sobre os níveis de nitratos, nitritos e N-nitrosaminas em alguns alimentos