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1.
Gac. méd. Méx ; 155(supl.1): 56-61, dic. 2019. tab
Article in Spanish | LILACS | ID: biblio-1286566

ABSTRACT

Resumen Introducción: La osteoartritis de cadera es una enfermedad articular inflamatoria de bajo grado y etiología múltiple que tiene un manejo conservador limitado y poco explorado. La aplicación de toxina botulínica tipo A (BoNT-A) produce en el músculo aplicado una parálisis flácida temporal, delimitable y reversible, que aplicada de manera estratégica logra liberar estrés mecánico y dolor Objetivo: Evaluar el efecto en la percepción de dolor, funcionalidad y rigidez y los cambios en la flexión, rotación interna y externa, antes y 90 días después de la aplicación de BoNT-A. Métodos: Estudio clínico, experimental, longitudinal, abierto, con un total de 35 pacientes y 45 caderas tratadas. Se aplicó BoNT-A de 500 U en músculos ilíaco, músculo aductorbrevis y longus. Resultados: Se utilizó la prueba de Wilcoxon comparando los puntajes de evaluación en los días 0 a 90 observando disminución significativa del dolor referido (p < 0.0001), rigidez (p < 0.002), mejoró la función percibida (p < 0.001) y los arcos de movilidad: flexión, rotación interna y externa (p < 0.0001). Conclusiones: El tratamiento con BoNT-A otorga una opción conservadora y segura para el manejo de los síntomas y restricción física causada por la OA de cadera.


Abstract Introduction: Osteoarthritis (OA) of the hip is a low-grade inflammatory disease of multiple etiology that has a limited conservative management and insufficiently explored. The application of botulinum toxin type A (BoNT-A) produces in the applied muscle a temporary, delimitable and reversible flaccid paralysis, which applicated in a strategic way achives to reduce mechanical stress and pain. Objective: To evaluate the effect on pain perception, functionality and rigidity and changes in flexibility, internal and external rotation, before and 90 days after the application of BoNT-A. Methods: Clinical, experimental, longitudinal, open study, with a total of 35 patients and 45 hips treated. BoNT-A of 500 U was applied in iliac, adductor brevis and longus muscles. Results: The Wilcoxon test was used to compare the evaluation scores on days 0-90, observing the decrease in referred pain (p < 0.0001), rigidity (p < 0.002), improved perceived function (p < 0.001) and mobility arcs: flexion, internal and external rotation (p < 0.0001). Conclusions: The treatment with BoNT-A provides a conservative and safe option for the management of symptoms and physical restraint caused by hip OA.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Osteoarthritis, Hip/drug therapy , Botulinum Toxins, Type A/therapeutic use , Conservative Treatment , Neuromuscular Agents/therapeutic use , Osteoarthritis, Hip/physiopathology , Longitudinal Studies , Range of Motion, Articular/drug effects
2.
Rev. salud pública ; 18(6): 986-995, nov.-dic. 2016. tab
Article in English | LILACS | ID: biblio-962040

ABSTRACT

ABSTRACT Objective The aim of this study is to verify the prevalence of avascular necrosis (AVN) in pediatric patients with sickle cell anemia and hip dysfunction, and to evaluate the presence of associated risk factors. Method A cross-sectional study was conducted in a group of 92 patients with sickle cell disease and hip dysfunction. Clinical and sociodemographic characteristics were collected, and laboratory variables were evaluated. All the subjects underwent radiographic and clinical evaluation of the hip. The participants were divided into two groups: the "AVN Group" consisting of patients with AVN, and the "Comparison Group" without AVN. Both groups were evaluated in search of factors associated with osteonecrosis of the femoral head. Results 43 (46.7 %) out of 92 individuals presented hip dysfunction, and 13 were diagnosed with AVN (30.2 %). Comparison between groups showed significant differences in time of diagnosis, previous trauma, presence of pain, and mean values of functional scores. Higher percentage rates of fetal hemoglobin, higher platelet counts and lower rates of total hemoglobin were perceived in the Comparison Group. Conclusions Pediatric patients with sickle cell anemia with hip dysfunction present a prevalence of 39.4 % of osteonecrosis of the femoral head. This was associated with a longer time of diagnosis (97 months), previous trauma in 92 % of patients, and a mean Charnley score of 15 points. Also, an association with lower rate of fetal hemoglobin (7.2 versus 11.8) was found, which supports the hypothesis that fetal hemoglobin may function as a protective factor against avascular necrosis.(AU)


RESUMEN Objetivo El objetivo de este estudio es confirmar la prevalencia de necrosis avas-cular (AVN) en pacientes con anemia de células falciformes, así como disfuncio-nes de cadera en la infancia, además de evaluar la presencia de factores de ries-go en estos individuos. Métodos Se realizó un estudio de corte transversal en un grupo de 92 pacientes con enfermedad falciforme y disfunción de cadera. Se hizo una recolección de caracte-rísticas clínicas y sociodemográficas, y se realizó un análisis de las variables encon-tradas en laboratorio. Todos los sujetos se sometieron a evaluación clínica y radio-gráfica de la cadera, y fueron divididos en dos grupos: el "Grupo AVN" que consistía de pacientes con AVN y el "Grupo Comparativo" sin AVN. Se evaluó ambos grupos con el fin de encontrar factores asociados con la osteonecrosis de cabeza femoral. Resultados 43 (46.7 %) de los 92 individuos presentaron disfunción en la cadera y 13 de ellos recibieron un diagnóstico de AVN (30.2 %). La comparación entre los dos grupos mostró diferencias importantes en el tiempo de diagnóstico, trauma previo, presencia de dolor, y media de valores en los puntajes funcionales. El Grupo Com-parativo evidenció valores porcentuales más altos de hemoglobina fetal, así como un conteo de plaquetas más alto y valores menores de hemoglobina total. Conclusiones Entre los pacientes pediátricos con anemia falciforme y con disfun-ción de cadera se presenta una prevalencia de 39.4 % de osteonecrosis de cabeza femoral, lo que está asociado a un tiempo mayor de diagnóstico (97 meses), trau-ma previo en 92 % de los pacientes, y valores de puntaje medio de Chanrley de 15 puntos. También se encontró una asociación con valores menores de hemog-lobina fetal (7.2 versus 11.8), lo cual respalda la hipótesis de que la hemoglobina fetal puede funcionar como un factor de protección contra la necrosis avascular.(AU)


Subject(s)
Humans , Osteonecrosis/epidemiology , Osteoarthritis, Hip/physiopathology , Anemia, Sickle Cell/physiopathology , Cross-Sectional Studies/instrumentation , Risk Factors
3.
J. bras. med ; 101(02): 47-52, mar.-abr. 2013. ilus, tab
Article in Portuguese | LILACS | ID: lil-686294

ABSTRACT

A osteoartrite (OA) é a causa mais frequente de doença crônica musculoesquelética, sendo sem dúvida a maior causa de limitação das atividades diárias entre os idosos. Atualmente, cerca de 40% dos adultos com idade superior a 70 anos sofrem de OA do joelho; destes, 80% apresentam limitações de movimento e em 25% as atividades diárias estão comprometidas. Nas últimas décadas têm ocorrido avanços na terapêutica da osteoartrite


Osteoarthritis (OA) is the most common cause of chronic musculoskeletal disease and the most prevalent reason for the limitation of daily activities of the elderly population. Currently, about 40% of adults aged over 70 suffer from OA of the knee. Of these, 80% suffer from limitations in motion and 25% are engaged to carry out their daily activities. In recent decades there have been advances in the treatment of osteoarthritis


Subject(s)
Humans , Male , Female , Osteoarthritis, Knee/physiopathology , Osteoarthritis, Knee/drug therapy , Osteoarthritis, Hip/physiopathology , Osteoarthritis, Hip/drug therapy , Anti-Inflammatory Agents , Acetaminophen/therapeutic use , Knee Joint , Glucosamine/administration & dosage , Osteoarthritis/rehabilitation , Patient Education as Topic , Viscosupplementation , Weight Loss
4.
Acta ortop. bras ; 21(2): 120-122, mar.-abr. 2013.
Article in Portuguese | LILACS | ID: lil-676854

ABSTRACT

A osteoartrite (OA), forma mais comum de doença articular, afeta principalmente quadris, joelhos, mãos e pés, levando a grande incapacidade e perda de qualidade de vida, sobretudo na população idosa. A importância desta doença cresce a cada ano, na medida em que observamos uma tendência de envelhecimento da população brasileira, com grande aumento da população idosa em relação aos mais jovens. O progressivo entendimento da fisiopatologia da OA, a percepção de que o processo não é puramente mecânico e/ou de envelhecimento, e o esclarecimento das vias inflamatórias envolvidas levaram, recentemente, à aplicação clínica de vários outros medicamentos e medidas. Esta atualização tem como objetivo expor os mais recentes conceitos sobre a fisiopatologia e tratamento da OA.


Osteoarthritis (OA), the most common form of joint disease, affects mainly the hips, knees, hands and feet, leading to severe disability and loss of quality of life, particularly in the elderly population. Its importance grows every year with the aging of the population, with a large increase in the elderly population compared to younger patients. The progressive understanding of the pathophysiology of OA, the perception that the process is not purely mechanical and/or aging, and clarification of the inflammatory pathways involved led recently to the clinical application of various drugs and other measures. This update aims to expose the current concepts on the pathophysiology and treatment of OA.


Subject(s)
Humans , Male , Female , Aging , Arthritis/physiopathology , Arthritis/rehabilitation , Osteoarthritis, Knee/physiopathology , Osteoarthritis, Knee/rehabilitation , Osteoarthritis, Hip/physiopathology , Osteoarthritis, Hip/rehabilitation , Quality of Life
5.
Fisioter. pesqui ; 16(4): 357-362, out.-dez. 2009. ilus, tab, graf
Article in Portuguese | LILACS | ID: lil-569659

ABSTRACT

O objetivo deste estudo foi comparar características espaciais, temporais com osteoartrose de quadril com e sem o auxílio de dispositivo (bengala). O caso é o de um sujeito com osteoartrose de quadril esquerdo de 63 anos, 97,8 kg e 1,76 m. Um sistema de reconstrução tridimensional de movimento foi utilizado para análise da marcha. Foram registrados três ciclos completos da marcha com e sem a utilização da bengala, sendo analisadas variáveis espaciais, temporais e espaço-temporais. Foi feita análise estatística, com nível de significância de 5%. Os principais resultados indicam que o comprimento de passo direito (CPD) e esquerdo (CPE), bem como o comprimento total do ciclo, foram superiores com o uso da bengala durante a marcha; o CPE foi significativamente maior do que o CPD quando o sujeito utilizava a bengala; todas as variáveis temporais foram estatisticamente menores com o uso da bengala; a cadência da marcha e a velocidade foram estatisticamente superiores com a bengala. Pode-se concluir que o uso da bengala gerou diferenças significativas no comportamento das variáveis espaciais, temporais e espaço-temporais durante a marcha, melhorando de forma significativa a eficiência do movimento do paciente com osteoatrose de quadril...


The purpose of this study was to compare cane-assisted and non-assisted gait temporal, spatial and spatio temporal features in a patient with hip osteoarthrosis. The patient studied, with left hip osteoarthrosis, was 63 years old and had 97.8 kg and 1.76 m. A three-dimensional analysis system was used for the analysis of gait. Three complete gait cycles with and without cane assistance were recorded, where temporal, spatial and spatio temporal variables were analysed. Descriptive statistics was used with the level of significance set at 5%. Main results show that left step length (LSL), right step length (RSL) and stride length were greater during cane assisted gait; LSL was significantly longer than RSL when the patient used the cane; all temporal variables were statistically lesser in cane-assisted gait; and cadence and walking speed were statistically higher during cane-assisted gait. It may thus be said that use of the cane by the patient with hip osteoarthrosis caused significant differences in spatial, temporal and spatio temporal variables during gait and significantly improved efficiency of the movement...


Subject(s)
Humans , Male , Aged , Canes , Gait , Osteoarthritis, Hip/physiopathology
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