Intestinal obstruction due to malign breast neoplasm and peritoneal carcinomatosis: a case report

Peritoneal carcinomatosis due to breast cancer is rare and gastrointestinal tract involvement is also unusual. Symptoms are unspecific and can begin many years after the primary tumor. Investigation of carcinomatosis origin is mandatory as breast cancer carcinomatosis can relieve partially or totally with chemo and hormonal therapy. A case of colonic obstruction due to carcinomatosis secondary to breast cancer is reported, emphasizing its diagnostic aspects and treatment. (AU)

A carcinomatose peritoneal secundária ao câncer de mama é entidade rara e o comprometimento do trato gastrointestinal é pouco frequente. A sintomatologia bastante inespecífica dificulta o diagnóstico e os sintomas podem surgir vários anos após o aparecimento do tumor primário. O diagnóstico da origem da carcinomatose é fundamental, pois quando a doença é secundária à neoplasia de mama, pode ocorrer remissão parcial e até total da doença com quimio e hormonioterapia. Relata-se caso de obstrução colônica devido a carcinomatose peritoneal secundária a neoplasia maligna de mama, com ênfase em seu diagnóstico e tratamento. (AU)

Endometrioid adenocarcinoma 13 years after total abdominal hysterectomy and bilateral salpingo-oophorectomy

Malignant transformation is an infrequent complication of endometriosis. As endometriosis is an ectopic endometrium, hyperestrogenism may cause hyperplasia or transformation into cancer. We describe a case of a 68-year-old woman who underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy for endometriosis. She was subsequently placed on estrogen-only replacement therapy. She presented with left-sided pelvic mass and shortness of breath. Computed tomography of chest, pelvis, and abdomen, demonstrated right-sided pleural effusion and soft tissue mass in the pelvis. Pleural effusion was tapped and biopsy from the peritoneal mass showed metastatic adenocarcinoma; immunohistochemistry findings favored endometrioid adenocarcinoma. She was treated by 6 cycles of Carboplatin/Paclitaxel and responded well. Unopposed estrogen stimulation may lead to premalignant or malignant transformation in the residual foci of endometriosis. Therefore, the addition of progestins to estrogen replacement therapy should be considered in women who have undergone hysterectomy with oophorectomy due to endometriosis

Peritoneal carcinomatosis computerized tomography scans findings and causes

To study the causes and Computerized Tomography Scan findings in patients with peritoneal carcinomatosis. A retrospective review of Computerized Tomography Scans in 26 patients with proven peritoneal carcinomatosis was conducted from 1997 to 2002. In 22 patients, there was proven primary malignant tumor and patients presented for follow-up studies. In four patients, the primary tumor was diagnosed at the time of presentation, looking for distribution of peritoneal thickening, ascitic fluid, and its extension. Diffuse peritoneal thickening and enhancement was seen in scans of all patients. Ascites was seen in 24 patients with extension to Douglas pouch in four patients. The primary tumor responsinle for peritoneal involvement was ovarian in 12 patients, colonic in eight, pancreatic in three, breast in one and unknown primary in two patients. Peritoneal thickening, enhancement, and ascites are the commonest findings in peritoneal involvement by malignancy 'peritoneal carcinomatosis'. Ovarian carcinoma followed by colonic are the commonest primary tumors to cause peritoneal carcinomatosis. The Computerized Tomography Scan is the imaging modality of choice to show the changes in perritoneal carcinomatosis

Síndrome de Caroli e carcinomatose peritoneal / Caroli's syndrome and peritoneal carcinomatosis

A Síndrome de Caroli é uma entidade incomum caracterizada pela presença de dilatações císticas da árvore biliar intra-hepática e fibrose hepática congênita. Pode comportar-se como condição pré-maligna, evoluindo em alguns casos para colangiocarcinoma. Relatamos um caso diagnosticado em paciente do sexo masculino, 37 anos, complicado por carcinomatose peritoneal de sítio desconhecido, fazendo também revisão da literatura

Primary peritoneal mesothelioma.

A patient with primary peritoneal mesothelioma who had occupational exposure to asbestos 30 years ago is reported. The disease was progressive and the patient died 12 months after the diagnosis.