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Deficiencia de prostaciclina durante la gestación: ¿podemos hablar de un síndrome? / Prostacyclin during pregnancy: can we talk about a syndrome?

Campos P., Germán A; Rodríguez A., Juan Guillermo; Ríos R., Raúl; Guerra B., Francisco A.

Rev. chil. obstet. ginecol ; 58(1): 52-61, 1993. tab, ilus

Article in Spanish | LILACS | ID: lil-119882

Subject(s)

Humans , Female , Pregnancy , Epoprostenol/deficiency , Prostaglandins/biosynthesis , Thromboxanes/biosynthesis , Hematologic Diseases/metabolism

An aqueous extract of guaraná (Paullinia cupana) decreases platelet thromboxane synthesis

Bydlowski, S. P; D'Amico, E. A.; Chamone, D. A. F.

Braz. j. med. biol. res ; 24(4): 421-4, 1991. tab

Article in English | LILACS | ID: lil-99472

ABSTRACT

The effects of an aqueous extract of guaraná (Paullinia cupana) on rabbit platelet aggregation and thromboxane synthesis were examined. The guaraná extract (100 mg/ml) and fractions separated by TLC (origin and xanthines) decreased platelet aggregation (37.27 and 31% of control values, respectively) and platelet thromboxane formation from [14C]-arachidonic acid (78, 70 and 50% of control values respectively). The decreased thromboxane synthesis could be responsible, at least in part, for the antiaggregatory action of guaraná

Subject(s)

Animals , Rabbits , Plant Extracts/pharmacology , Plants, Medicinal , Platelet Aggregation Inhibitors , Thromboxanes/biosynthesis , Platelet Aggregation

Subject(s)

ABSTRACT

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